1:	Med Oral Patol Oral Cir Bucal. 2009 Aug 1;14(8):e365-e370. Presence of fibronectin peptides in saliva of patients with Sjögren's Syndrome: A potential indicator of salivary gland destruction. Silvestre FJ, Puente A, Bagán JV, Castell JV. Universidad de Valencia, Clínica Odontológica Universitaria, C/Gascó Oliag 1. 46010–Valencia, Spain, Francisco.silvestre@uv.es. Objective:The purpose of this preliminary study was to monitor the degree of destruction of salivary glands in Sjögren disease by the detection of fibronectin peptides in patients' saliva. Study design:The sample consisted of 10 subjects divided in 2 groups, one with Sjögren disease and a control group. Saliva samples were submitted to an inmunodetection analysis. In addition, non pathological salivary glands, obtained from 2 subjects who underwent minor oral surgery, were incubated with leukocyte homogenates and analysed to compare the obtained fragments. Results:The inmunodetection analysis of Sjögren saliva revealed multiple protein bands, including fibronectin, that were not present in saliva from healthy individuals. The inmunostained bands varied depending on the course of the disease, showing more fibronectin fragments in an active phase. Furthermore, results obtained from the non-pathological glands incubated with leukocyte homogenates were similar to those revealed in saliva from Sjögren patients. Conclusion:The presence of fibronectin peptides in Sjögren patients' saliva can constitute a method to monitor activity in Sjögren's disease.
2:	Med Oral Patol Oral Cir Bucal. 2009 Aug 1;14(8):e371-e375. Oral lesions in 166 patients with cutaneous psoriasis: A controlled study. Costa SC, Hirota SK, Takahashi MD, Andrade Jr H, Migliari DA. Universidade de Sã o Paulo, Faculdade de Odontologia, Departamento de Estomatologia, Disciplina de Estomatologia Clínica, Av. Prof. Lineu Prestes, 2227, Cidade Universitária, São Paulo, SP – Brazil 05508–000, damiglia@usp.br. Objectives. This study was aimed to test if the frequency of oral lesions bears statistical correlation or not with the condition of cutaneous psoriasis. Study design. Two groups were examined, one made up of 166 patients with skin psoriasis and the other with the same number of individuals with a negative history of skin diseases (control group), matched by age, race, and sex. Patients with psoriasis were grouped according to their having localized or generalized forms of the disease. The oral mucosa was thoroughly examined in both groups. Data were analyzed using chi-square test, Fisher's test, the odds ratio (OR) with a 95% confidence interval (CI), and the Ryan-Holm step-down Bonferroni procedure. The overall significance was set at P </= 0.05. Results. The oral lesions significantly associated with psoriasis were fissured tongue (FT, OR = 2.7; 95% CI: 1.3-5.6), and geographic tongue (GT, OR = 5.0; 95% CI: 1.5-16.8). Other factors analyzed, such as topical and/or systemic medication for treatment of psoriasis versus nontreated patients, and localized versus generalized forms of psoriasis presented no statistical association with the frequency of FT or GT lesions (p>0.05). Conclusions. Patients with psoriasis presented no specific oral lesion different from those seen in the control group. Although further investigation is warranted to establish whether or not either FT or GT can be characterized as an oral expression of psoriasis, the present investigation did find for both these types of lesions that the frequency of each bore a statistically significant relation with the presence of cutaneous psoriasis.
3:	Med Oral Patol Oral Cir Bucal. 2009 Aug 1;14(8):e376-e383. Dental erosion in alcoholic patients under addiction rehabilitation therapy. Manarte P, Manso MC, Souza D, Frias-Bulhosa J, Gago S. Faculdade de Ciencias da Saúde – Universidade Fernando Pessoa R. Carlos da Maia, 296 4200–150 Porto, Portugal, patmon@ufp.edu.pt. Objective: To determine the occurrence and severity of dental erosion in alcoholic patients undergoing detoxification at the North Alcoholic Regional Centre (CRAN), Porto, Portugal, and to assess socioeconomic and behavioural covariates of dental erosion occurrence. Design: A cross-sectional descriptive study was carried out in one centre (CRAN) for addiction rehabilitation therapy in the north of Portugal. A sample of 1064 teeth was examined. The condition of the dental erosion was classified by means of severity and anatomic location, according to the Eccles and Jenkins dental erosion index, and a dichotomous outcome assessing the occurrence of dental erosion (severity dental erosion levels > 0 ). Dental erosion results were linked to data supplied by a questionnaire assessing socio-demographic characteristics, behaviour related to alcohol and drug use, including a history of drug and alcohol abuse, and oral health promotion using logistic multivariate regression analysis. Results: Enamel and/or dentine erosion lesions were present on 49.4% of the teeth. Among these, 36.9% of occlusal surfaces presented dental erosion with a severity level of 1 , 11.4% with a severity level 2 and 1.1% with a severity level 3. The highest occurrence of severity level 3 was found to exist in palatal dental surfaces (1.9%). Dental erosion on teeth surfaces was found to be independently associated with intra oral location (by arch, tooth type), patients' socio-demographic characteristics, behaviour associated with a history of alcohol and drug abuse, and oral health promotion. Maxillary teeth, more so than mandibular teeth, presented moderate to higher severity erosion injuries (Wilcoxon test; p< 0.001); and significant differences in the severity of dental erosion were found between anterior and posterior teeth, in both the maxillary and the mandibular arches (Friedman test, p< 0.001). Conclusions: Alcohol-dependent patients undergoing a detoxification programme presented a high occurrence and a low severity of dental erosion lesions.The palatal surfaces of the anterior teeth, followed by incisive/occlusal surfaces in both anterior and posterior teeth, respectively, were most affected by erosion injuries.
4:	Med Oral Patol Oral Cir Bucal. 2009 Aug 1;14(8):e384-e387. Periodontal status of HIV-positive patients. Doshi D, Ramapuram J, Anup N. Department of Community Dentistry Army College of Dental Sciences ACDS Nagar Chennapur–CRPF Road PO, Jai Jawahar Nagar Secunderabad, 500 087 Andhra Pradesh, India, doshidolar@yahoo.com. Objective: To assess the periodontal status of HIV positive individuals and to compare it with age-and gender-matched controls. Materials and Methods: The cross-sectional study comprised fifty-two HIV positive individuals and fifty-two controls. OHI-S and PI were recorded by a single pre-trained and pre-calibrated examiner. Results: Based on antiretroviral therapy use, mean OHI-S was higher among HIV positive females undergoing therapy. A significant gender difference was observed in the PI score among those on antiretroviral therapy, with females having a lower score (p = 0.04). Also, significant gender difference was observed in the mean PI score among HIV positive individuals, with males having a higher score. Conclusion: There was a significant difference in the overall mean OHI-S score among HIV positive individuals and controls (p = 0.03). However, no significant difference was observed when the overall PI score was calculated for both groups (p = 0.95).
5:	Med Oral Patol Oral Cir Bucal. 2009 Aug 1;14(8):e388-e392. Morphometric analysis of the dorsum linguae in patients with Oral Lichen Planus. Bermejo-Fenoll A, López-Jornet P, Camacho-Alonso F, Saura-Ingles A, Panchon-Ruiz A. Clínica odontológica. 2 planta Hospital Morales Meseguer, c/ Marqués de los Vélez s/n, 30008 Murcia, Spain, majornet@um.es. Objective: Morphometric study of the dorsum linguae in patients with Oral Lichen Planus (OLP). Material and Method: In 236 patients with a clinicopathologic diagnosis of OLP, 111 were found to have involvement of the dorsum linguae. For the purposes of the study, 41 of these cases were used, due to the availability of photographic records fulfilling quality conditions according to objective criteria. The experimental variable was defined as the proportion of affected dorsum linguae measured and calculated using the MIP4(R) computer software. Results: In 236 patients with OLP, the mucosa of the dorsum linguae was affected in 47.6% of the cases (total 111). The proportion of affected area was studied in 41 of these cases, 8 men (19.5%) and 33 women (80.5%). In 73% of these cases, the affected area was less than 50% of the total surface of the dorsum linguae. There were no statistically significant differences (p=0.495) in relation to age and proportion of lingual surface affected. On the other hand, significant statistical differences were found between the period of disease evolution and area of lingual involvement (p=0.044). Conclusion: Lingual involvement is frequent in patients with OLP, and manifests as de-papillate areas to the left and right of the median sulcus of tongue (occasionally linked by an isthmus) and having a certain " butterfly wing" symmetry.
6:	Med Oral Patol Oral Cir Bucal. 2009 Aug 1;14(8):e393-e397. Clinic and radiographical evaluation of non-syndromic hypodontia and hyperdontia in permanent dentition. Peker I, Kaya E, Darendeliler-Yaman S. Gazi University Faculty of Dentistry, Department of Oral Diagnosis and Radiology, 8. Cad. 82. Sok. 06510 Emek/Ankara–Turkey, drilkaypeker@gmail.com. Objectives: The purpose of this study was to evaluate the clinical and radiographical characteristics of non-syndromic hypodontia and hyperdontia in the permanent dentition. Study design: This study included 139 patients. Clinical and radiographical examinations were carried out by two examiners. Number and localization of missing or supernumerary teeth, and pathologies associated with the teeth, were recorded. Other teeth in the mouth were also examined for the presence of additional dental anomalies. Results: A total of 256 congenitally missing teeth were observed in 102 patients, and 73 supernumerary teeth were observed in 37 patients. The rate of missing teeth was much higher in females (67.6 %) than males (32.4 %) and in the maxilla (64.5 %) than mandible (35.5 %). The rate of supernumerary teeth was slightly higher in males (59.5 %) than females (40.5 %) and in maxilla (53.4 %) than mandible (46.6 %). The most common hypodontia type was mild to moderate hypodontia (62.7 %) and the most observed hyperdontia was a single supernumerary tooth (54.1 %). Microdontia, talon cusp, taurodontic molars were observed in 18.6 % of patients with hypodontia; and microdontia and dilacerated molars were observed in 8.1 % of patients with hyperdontia. Conclusions: Although missing and supernumerary teeth are asymptomatic in most cases, they may lead to malocclusions, aesthetic, functional and psychological problems.
7:	Med Oral Patol Oral Cir Bucal. 2009 Aug 1;14(8):e398-e401. Lemierre's Syndrome: A serious complication of an odontogenic infection. Rosado P, Gallego L, Junquera L, de Vicente JC. Oviedo University, Dental School,Catedrático José Serrano Street, 33009 Oviedo, Spain, Junquera@uniovi.es. Necrobacillosis, postanginal septicaemia or Lemierre's Syndrome is characterised by suppurative thrombophlebitis of the internal jugular vein with embolization to several sites, including the lungs. We report the case of a 38-year-old man who was initially hospitalized because of odontogenic cellulitis. Given the deterioration of his clinical state (septic shock and multiple organ failure), neck computed tomography was performed, revealing both cervical and parotid abscesses, and thrombosis of the right internal jugular vein. Streptococcus salivarius was isolated. The patient was treated with intravenous antibiotics, and surgical drainage and after 6 weeks of treatment, recovered completely. Lemierre's Syndrome is an uncommon, but potentially lethal complication of an odontogenic infection. The case reported here is interesting since the pathogen and the site of primary infection are unusual. Fusobacterium necrophorum is the most common pathogen in Lemierre's Syndrome, and to the best of our knowledge there are no similar case reports with Streptococcus salivarius as the causative bacteria. Early recognition and high-dose antibiotics are critical elements in reducing mortality.
8:	Med Oral Patol Oral Cir Bucal. 2009 Aug 1;14(8):e402-e407. Augmentation procedures for deficient edentulous ridges, using onlay autologous grafts: An update. Maestre-Ferrín L, Boronat-López A, Peñarrocha-Diago M, Peñarrocha-Diago M. Clínicas odontológicas Gascó Oliag, 1 46021– Valencia (Spain), maria.penarrocha@uv.es. The purpose of this review was to analyze publications related to augmentation procedures using autologous onlay grafts and to evaluate the survival/success rates of implants placed in the augmented areas. An automated search was made in Medline, of clinical publications from 2002 to 2007, including at least 5 patients and with a minimum follow-up of 6 months. Ten papers were included. These suggested that grafts are indicated when the height of the alveolar crest is less than 5mm, or the width less than 4mm. The surface resorption of grafts protected by guided bone regeneration membranes was less than for unprotected grafts. Calvarial grafts suffered less resorption than did iliac grafts. The healing period of the graft until implant placement was, in most cases, 4-6 months. The most frequent complications in the recipient site were wound dehiscences. Prosthetic loading time was, in almost all patients, 3 months after implant placement. Implant survival rate ranged from 97.1% to 100%. Although , due to the difficulty in finding homogenous studies, the sample is small, we can conclude that autologous onlay block bone grafts are an effective procedure for alveolar crest augmentation; graft surface resorption is reduced when the grafts are protected by regeneration membranes; few complications arise from the procedure; and the success rate for implants placed in the reconstructed area is between 89.5 and 95.7%.
9:	Med Oral Patol Oral Cir Bucal. 2009 Aug 1;14(8):e408-e410. Bilateral mental nerve neuropathy as the sole presenting symptom of Burkitt's Lymphoma. Martos-Díaz P, Bances-Del-Castillo R, Vidal-Laso R, Mancha-de-la-Plata M, Cho-Lee GY, Naval-Gías L. Ifara 75. Santa Cruz de Tenerife. Spain, plmartos9@hotmail.com. There are several pathologies that may cause alteration of the lower lip sensation, therefore a differential diagnosis is needed. Among these pathologies, we have focused on intrabone growing tumours such as Burkitt's Lymphoma. Burkitt's Lymphoma is a malignant tumour of B-Cell lymphocyte origin, classified as a Non-Hodgkin's Lymphoma. Three clinical subtypes are described: endemic, sporadic and HIV associated. It is characterized by very fast growing, undifferentiated lymphocytes and bone marrow infiltration. A high incidence of Burkitt's Lymphoma has been reported in African children. It is known to have a good response to radiotherapy and chemotherapy treatment. This report describes the case of a 29 year-old Spanish man diagnosed with Burkitt's Lymphoma, in which his first and only symptom was bilateral anaesthesia of the lower lip. We have also described the clinical evolution, steps for diagnosis and treatment.
10:	Med Oral Patol Oral Cir Bucal. 2009 Aug 1;14(8):e411-e415. Analgesic efficacy of lysine clonixinate, paracetamol and dipyrone in lower third molar extraction. A randomized controlled trial. Noronha VR, Gurgel GS, Alves LC, Noman-Ferreira LC, Mendonça LL, Aguiar EG, Abdo EN. Faculdade de Odontologia da Universidade Federal de Minas Gerais, Av. Antonio Carlos, 6627 Belo Horizonte, Minas Gerais, Brasil, evandro.abdo@gmail.com. Objective: The purpose of this study is to compare the analgesic effect of lysine clonixinate, paracetamol and dipyrone after lower third molar extraction. Material and methods: The sample consisted of 90 individuals with clinical indication for inferior third molar extraction. The mean age of the sample was 22.3 years (DP +/-2.5). The individuals received the medication in unidentified bottles along with the intake instructions. The postoperative pain parameters were measured according to the Visual Analogical Scale (VAS) and the data was evaluated using the Kruskal-Wallis Test and Friedman Test, with the latter used to test different time intervals for each one of the drugs. Results: The final sample consisted of 64 individuals, including 23 males (45.9%) and 41 females (64.1%) The mean age of the entire sample was 22.3 years (+/-2.5). The average length of the procedures was 33.9 minutes (+/-9.8). The distribution of mean values for this variable showed little variance for the different drugs (p=0.07). Conclusion: Lysine Clonixinate did not show any substantial impact on the postoperative pain control when compared to other drugs.