Fernández-Olavarría A, Mosquera-Pérez R, Díaz-Sánchez RM, Serrera- Figallo MA, Gutiérrez-Pérez JL, Torres-Lagares D. The role of serum biomarkers in the diagnosis and prognosis of oral cancer: A systematic review. J Clin Exp Dent. 2016;8(2):e184-93.

 

doi:10.4317/jced.52736

http://dx.doi.org/doi:10.4317/jced.52736

 

References

1. Jemal A, Siegel R, Ward E, Hao Y, Xu J, Thun MJ. Cancer statistics, 2009. CA Cancer J Clin. 2009; 59:225-49.
http://dx.doi.org/10.3322/caac.20006
PMid:19474385

 

2. Tanaka T, Ishigamori R. Understanding carcinogenesis for fighting oral cancer. J Oncol. 2011;2011:603740.
http://dx.doi.org/10.1155/2011/603740
PMid:21772845 PMCid:PMC3136173

 

3. Mishra R. Biomarkers of oral premalignant epithelial lesions for clinical application. Oral Oncol. 2012;48:578-84.
http://dx.doi.org/10.1016/j.oraloncology.2012.01.017
PMid:22342569

 

4. Kademani D. Oral cancer. Mayo Clin Proc. 2007;82:878-87.
http://dx.doi.org/10.4065/82.7.878
PMid:17605971

 

5. Gupta PC, Murti PR, Bhonsle RB, Mehta FS, Pindborg JJ. Effect of cessation of tobacco use on the incidence of oral mucosal lesions in a 10-yr follow-up study of 12,212 users. Oral Dis. 1995;1:54-8.
http://dx.doi.org/10.1111/j.1601-0825.1995.tb00158.x
PMid:7553382

 

6. Bundgaard T, Bentzen SM, Wildt J. The prognostic effect of tobacco and alcohol consumption in intra-oral squamous cell carcinoma. Eur J Cancer B Oral Oncol. 1994;30B:323-8.
http://dx.doi.org/10.1016/0964-1955(94)90033-7

PMid:7703801

 

7. Sawant SS, Zingde SM, Vaidya MM. Cytokeratin fragments in the serum: Their utility for the management of oral cancer. Oral Oncol. 2008;44:722-32.
http://dx.doi.org/10.1016/j.oraloncology.2007.10.008
PMid:18203649

 

8. Bijian K, Mlynarek AM, Balys RL, Jie S, Xu Y, Hier MP, et al. Serum proteomic approach for the identification of serum biomarkers contributed by oral squamous cell carcinoma and host tissue microenvironment. J Proteome Res. 2009;8:2173-85.
http://dx.doi.org/10.1021/pr800979e
PMid:19284786

 

9. Cordes C, Von Lingen J, Gorogh T, Ambrosch P, Gottschlich S, Hoffmann M. Molecular and immunological aspects of p53 and p53-autoantibodies in head and neck squamous cell carcinoma. Oncol Rep. 2009;22:1299-303.
http://dx.doi.org/10.3892/or_00000568
PMid:19885580

 

10. Kato H, Torigoe T. Radioimmunoassay for tumor antigen of human cervical squamous cell carcinoma. Cancer. 1977;40:1621-8.
http://dx.doi.org/10.1002/1097-0142(197710)40:4<1621::AID-CNCR2820400435>3.0.CO;2-I

PMid:332328

 

11. Hoffmann-Fazel A, Hoffmann M, Gottschlich S, Maass JD, Rudert H, Maune S. Cyfra 21-1 in diagnosis of distant metastases of head and neck carcinoma. Anticancer Res. 2003;23:917-20.
PMid:12820323

 

12. Joshi M, Patil R. Estimation and comparative study of serum total sialic acid levels as tumor markers in oral cancer and precancer. J Cancer Res Ther. 2010;6:263-6.
http://dx.doi.org/10.4103/0973-1482.73339
PMid:21119250

 

13. Doweck I, Barak M, Uri N, Greenberg E. The prognostic value of the tumour marker cyfra 21-1 in carcinoma of head and neck and its role in early detection of recurrent disease. Br J Cancer. 2000;83:1696-701.
http://dx.doi.org/10.1054/bjoc.2000.1502
PMid:11104568 PMCid:PMC2363457

 

14. Clementini M, Morlupi A, Agrestini C, Barlattani A. Immediate versus delayed positioning of dental implants in guided bone regeneration or onlay graft regenerated areas: A systematic review. Int J Oral Maxillofac Surg. 2013;42:643-50.
http://dx.doi.org/10.1016/j.ijom.2013.01.018
PMid:23481543

 

15. Chang KP, Wu CC, Fang KH, Tsai CY, Chang YL, Liu SC, et al. Serum levels of chemokine (C-X-C motif) ligand 9 (CXCL9) are associated with tumor progression and treatment outcome in patients with oral cavity squamous cell carcinoma. Oral Oncol. 2013;49:802-7.
http://dx.doi.org/10.1016/j.oraloncology.2013.05.006
PMid:23769451

 

16. Chang KP, Chang YT, Liao CT, Yen TC, Chen IH, Chang YL. Prognostic cytokine markers in peripheral blood for oral cavity squamous cell carcinoma identified by multiplexed immunobead-based profiling. Clin Chim Acta. 2011;412:980-7.
http://dx.doi.org/10.1016/j.cca.2011.02.002
PMid:21315702

 

17. Inal E, Laçin M, Asal K, Ceylan A, Köybaşioğlu A, Ileri F, et al. The significance of ferritin, lipid-associated sialic acid, CEA, squamous cell carcinoma (SCC) antigen, and CYFRA 21-1 levels in SCC of the head and neck. Kulak Burun Bogaz Ihtis Derg. 2004;12:23-30.
PMid:16010093

 

18. Madsen EL, Rissanen A, Bruun JM, Skogstrand K, Tonstad S, Hougaard DM, et al. Weight loss larger than 10% is needed for general improvement of levels of circulating adiponectin and markers of inflammation in obese subjects: A 3-year weight loss study. Eur J Endocrinol. 2008;158:179-87.
http://dx.doi.org/10.1530/EJE-07-0721
PMid:18230824

 

19. Guo XH, Wang JY, Gao Y, Gao M, Yu GY, Xiang RL, et al. Decreased adiponectin level is associated with aggressive phenotype of tongue squamous cell carcinoma. Cancer Sci. 2013;104:206-13.
http://dx.doi.org/10.1111/cas.12077
PMid:23181352

 

20. Perretti M, Flower RJ. Annexin 1 and the biology of the neutrophil. J Leukoc Biol. 2004;76:25-9.
http://dx.doi.org/10.1189/jlb.1103552
PMid:14966195

 

21. Faria PC, Sena AA, Nascimento R, Carvalho WJ, Loyola AM, Silva SJ. Expression of annexin A1 mRNA in peripheral blood from oral squamous cell carcinoma patients. Oral Oncol. 2010;46:25-30.
http://dx.doi.org/10.1016/j.oraloncology.2009.09.003
PMid:19833546

 

22. Feng XY, Li JH, Li JZ, Han ZX, Xing RD. Serum SCCA, cyfra 21-1, EGFR and cyclin D1 levels in patients with oral squamous cell carcinoma. Int J Biol Markers. 2010;25:93-8.
PMid:20586028

 

23. Capaccio P, Pruneri G, Carboni N, Pagliari AV, Quatela M, Cesana BM, Pignataro L. Cyclin D1 expression is predictive of occult metastases in head and neck cancer patients with clinically negative cervical lymph nodes. Head Neck. 2000;22:234-40.
http://dx.doi.org/10.1002/(SICI)1097-0347(200005)22:3<234::AID-HED5>3.0.CO;2-3

PMid:10748446

 

24. Khandavilli SD, Ceallaigh PO, Lloyd CJ, Whitaker R. Serum C-reactive protein as a prognostic indicator in patients with oral squamous cell carcinoma. Oral Oncol. 2009;45:912-4.
http://dx.doi.org/10.1016/j.oraloncology.2009.03.015
PMid:19502100

 

25. Tu HF, Liu CJ, Liu SY, Chen YP, Yu EH, Lin SC, et al. Serum decoy receptor 3 level: A predictive marker for nodal metastasis and survival among oral cavity cancer patients. Head Neck. 2011;33:396-402.
http://dx.doi.org/10.1002/hed.21467

PMid:20645287

 

26. Zhang L, Yang X, Pan HY, Zhou XJ, Li J, Chen WT, et al. Expression of growth differentiation factor 15 is positively correlated with histopathological malignant grade and in vitro cell proliferation in oral squamous cell carcinoma. Oral Oncol. 2009;45:627-32.
http://dx.doi.org/10.1016/j.oraloncology.2008.07.017
PMid:18805046

 

27. Schiegnitz E, Kammerer PW, Koch FP, Kruger M, Berres M, Al-Nawas B. GDF 15 as an anti-apoptotic, diagnostic and prognostic marker in oral squamous cell carcinoma. Oral Oncol. 2012;48:608-14.
http://dx.doi.org/10.1016/j.oraloncology.2012.01.020
PMid:22341306

 

28. Cordella C, Luebbers HT, Rivelli V, Gratz KW, Kruse AL. An evaluation of the preoperative hemoglobin level as a prognostic factor for oral squamous cell carcinoma. Head Neck Oncol. 2011;3:35.

PMid:21843350

 

29. Dinarello CA. Biologic basis for interleukin-1 in disease. Blood. 1996;87:2095-2147.
PMid:8630372

 

30. Brailo V, Vucicevic-Boras V, Lukac J, Biocina-Lukenda D, Zilic-Alajbeg I, Milenovic A, et al. Salivary and serum interleukin 1 beta, interleukin 6 and tumor necrosis factor alpha in patients with leukoplakia and oral cancer. Med Oral Patol Oral Cir Bucal. 2012;17:e10-5.
http://dx.doi.org/10.4317/medoral.17323
PMid:21743397 PMCid:PMC3448188

 

31. Watson NF, Spendlove I, Madjd Z, McGilvray R, Green AR, Ellis IO, et al. Expression of the stress-related MHC class I chain-related protein MICA is an indicator of good prognosis in colorectal cancer patients. Int J Cancer. 2006;118:1445-1452.
http://dx.doi.org/10.1002/ijc.21510
PMid:16184547

 

32. Tamaki S, Kawakami M, Ishitani A, Kawashima W, Kasuda S, Yamanaka Y, et al. Soluble MICB serum levels correlate with disease stage and survival rate in patients with oral squamous cell carcinoma. Anticancer Res. 2010;30:4097-101.
PMid:21036725

 

33. Liu CJ, Chang KW, Lin SC, Cheng HW. Presurgical serum levels of matrix metalloproteinase-9 and vascular endothelial growth factor in oral squamous cell carcinoma. Oral Oncol. 2009;45:920-5.
http://dx.doi.org/10.1016/j.oraloncology.2009.04.007
PMid:19502103

 

34. Tadbir AA, Purshahidi S, Ebrahimi H, Khademi B, Malekzadeh M, Mardani M, et al. Serum level of MMP-3 in patients with oral squamous cell carcinoma--lack of association with clinico-pathological features. Asian Pac J Cancer Prev. 2012;13:4545-8.
http://dx.doi.org/10.7314/APJCP.2012.13.9.4545
PMid:23167377

 

35. Rao VR, Krishnamoorthy L, Kumaraswamy SV, Ramaswamy G.Circulating levels in serum of total sialic acid, lipid-associated sialic acid, and fucose in precancerous lesion and cancer of the oral cavity. Cancer Detect Prev. 1998;22:237-40.
http://dx.doi.org/10.1046/j.1525-1500.1998.0OA04.x
PMid:9618045

 

36. Rajpura KB, Patel PS, Chawda JG, Shah RM. Clinical significance of total and lipid bound sialic acid levels in oral pre-cancerous conditions and oral cancer. J Oral Pathol Med. 2005;34:263-7.
http://dx.doi.org/10.1111/j.1600-0714.2004.00210.x
PMid:15817068

 

37. Li C, Zhao Y, Zhang W, Zhang W. Increased prevalence of T(H)17 cells in the peripheral blood of patients with head and neck squamous cell carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 201;112:81-9. http://dx.doi.org/10.1016/j.tripleo.2010.11.032
PMid:21458322

 

38. Sawant SS, Chaukar DA, Joshi SS, Dange PP, Kannan S, Kane S, et al. Prognostic value of tissue polypeptide antigen in oral squamous cell carcinoma. Oral Oncol. 2011;47:114-120.
http://dx.doi.org/10.1016/j.oraloncology.2010.11.005
PMid:21130025

 

39. Shang ZJ, Li JR, Li ZB. Circulating levels of vascular endothelial growth factor in patients with oral squamous cell carcinoma. Int J Oral Maxillofac Surg. 2002;31:495-8.
http://dx.doi.org/10.1054/ijom.2002.0284
PMid:12418564