Chandrangsu S, Sappayatosok K. p53, p63 and p73 expression and angiogenesis in keratocystic odontogenic tumors. J Clin Exp Dent. 2016;8(5):e505-11.

 

doi:10.4317/jced.52843

http://dx.doi.org/doi:10.4317/jced.52843

 

References

1. Mendes RA, Carvalho JF, van der Waal I. Biological pathways involved in the aggressive behavior of the keratocystic odontogenic tumor and possible implications for molecular oriented treatment - an overview. Oral Oncol. 2010;46:19-24.
http://dx.doi.org/10.1016/j.oraloncology.2009.10.009
PMid:20004133

 

2. Mateus GC, Lanza GH, de Moura PH, Marigo Hde A, Horta MC. Cell proliferation and apoptosis in keratocystic odontogenic tumors. Med Oral Patol Oral Cir Bucal. 2008;13:E697-702.
PMid:18978709

 

3. Maurette PE, Jorge J, de Moraes M. Conservative treatment protocol of odontogenic keratocyst: a preliminary study. J Oral Maxillofac Surg. 2006;64:379-83.
http://dx.doi.org/10.1016/j.joms.2005.11.007
PMid:16487797

 

4. Browne RM. The odontogenic keratocyst. Clinical aspects. Br Dent J. 1970;128:225-31.
http://dx.doi.org/10.1038/sj.bdj.4802449

PMid:5270271

 

5. Madras J, Lapointe H. Keratocystic odontogenic tumour: reclassification of the odontogenic keratocyst from cyst to tumour. J Can Dent Assoc. 2008;74:165-65h.
PMid:18353202

 

6. Johann AC, Caldeira PC, Caliari MV, Gomez RS, Aguiar MC, Mesquita RA. Metallothionein immunoexpression in non-syndromic and syndromic keratocystic odontogenic tumour. Med Oral Patol Oral Cir Bucal. 2015;20:e408-12.
http://dx.doi.org/10.4317/medoral.20418
PMid:25858080 PMCid:PMC4523252

 

7. Mendes RA, Carvalho JF, van der Waal I. Characterization and management of the keratocystic odontogenic tumor in relation to its histopathological and biological features. Oral Oncol. 2010;46:219-25.
http://dx.doi.org/10.1016/j.oraloncology.2010.01.012
PMid:20189443

 

8. Shear M. The aggressive nature of the odontogenic keratocyst: is it a benign cystic neoplasm? Part 2. Proliferation and genetic studies. Oral Oncol. 2002;38:323-31.
http://dx.doi.org/10.1016/S1368-8375(01)00066-5

PMid:12076694

 

9. Crowley TE, Kaugars GE, Gunsolley JC. Odontogenic keratocysts: a clinical and histologic comparison of the parakeratin and orthokeratin variants. J Oral Maxillofac Surg. 1992;50:22-6.
http://dx.doi.org/10.1016/0278-2391(92)90187-5

PMid:1370082

 

10. Zhao YF, Wei JX, Wang SP. Treatment of odontogenic keratocysts: a follow-up of 255 Chinese patients. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002;94:151-6.
http://dx.doi.org/10.1067/moe.2001.125694
PMid:12221380

 

11. Forssell K, Forssell H, Kahnberg KE. Recurrence of keratocysts. A long-term follow-up study. Int J Oral Maxillofac Surg. 1988;17:25-8.
http://dx.doi.org/10.1016/S0901-5027(88)80224-8

PMid:3127485

 

12. Langdon JD, Partridge M. Expression of the tumour suppressor gene p53 in oral cancer. Br J Oral Maxillofac Surg. 1992;30:214-20.
http://dx.doi.org/10.1016/0266-4356(92)90263-I

PMid:1380822

 

13. Miller C, Mohandas T, Wolf D, Prokocimer M, Rotter V, Koeffler HP. Human p53 gene localized to short arm of chromosome 17. Nature. 1986;319:783-4.
http://dx.doi.org/10.1038/319783a0
PMid:3005871

 

14. Piattelli A, Fioroni M, Santinelli A, Rubini C. P53 protein expression in odontogenic cysts. J Endod. 2001;27:459-61.
http://dx.doi.org/10.1097/00004770-200107000-00006
PMid:11503996

 

15. Gurgel CA, Ramos EA, Azevedo RA, Sarmento VA, da Silva Carvalho AM, dos Santos JN. Expression of Ki-67, p53 and p63 proteins in keratocyst odontogenic tumours: an immunohistochemical study. J Mol Histol. 2008;39:311-6.
http://dx.doi.org/10.1007/s10735-008-9167-0
PMid:18256893

 

16. Trink B, Okami K, Wu L, Sriuranpong V, Jen J, Sidransky D. A new human p53 homologue. Nat Med. 1998;4:747-8.
http://dx.doi.org/10.1038/nm0798-747
PMid:9662346

 

17. Lo Muzio L, Santarelli A, Caltabiano R, Rubini C, Pieramici T, Giannone N, et al. p63 expression correlates with pathological features and biological behaviour of odontogenic tumours. Histopathology. 2006;49:211-4.
http://dx.doi.org/10.1111/j.1365-2559.2006.02423.x
PMid:16879406

 

18. Dotsch V, Bernassola F, Coutandin D, Candi E, Melino G. p63 and p73, the ancestors of p53. Cold Spring Harb Perspect Biol. 2010;2:a004887.
http://dx.doi.org/10.1101/cshperspect.a004887
PMid:20484388 PMCid:PMC2926756

 

19. Potente M, Gerhardt H, Carmeliet P. Basic and therapeutic aspects of angiogenesis. Cell. 2011;146:873-87.
http://dx.doi.org/10.1016/j.cell.2011.08.039
PMid:21925313

 

20. Lo Muzio L, Santarelli A, Caltabiano R, Rubini C, Pieramici T, Fior A, et al. p63 expression in odontogenic cysts. Int J Oral Maxillofac Surg. 2005;34:668-73.
http://dx.doi.org/10.1016/j.ijom.2004.12.002
PMid:16053892

 

21. Weidner N, Semple JP, Welch WR, Folkman J. Tumor angiogenesis and metastasis--correlation in invasive breast carcinoma. N Engl J Med. 1991;324:1-8.
http://dx.doi.org/10.1056/NEJM199101033240101
PMid:1701519

 

22. Sappayatosok K, Maneerat Y, Swasdison S, Viriyavejakul P, Dhanuthai K, Zwang J, et al. Expression of pro-inflammatory protein, iNOS, VEGF and COX-2 in oral squamous cell carcinoma (OSCC), relationship with angiogenesis and their clinico-pathological correlation. Med Oral Patol Oral Cir Bucal. 2009;14:E319-24.
PMid:19300368

 

23. Ball VA, Righi PD, Tejada E, Radpour S, Pavelic ZP, Gluckman JL. p53 immunostaining of surgical margins as a predictor of local recurrence in squamous cell carcinoma of the oral cavity and oropharynx. Ear Nose Throat J. 1997;76:818-23.
PMid:9397628

 

24. Lo Muzio L, Campisi G, Farina A, Rubini C, Pastore L, Giannone N, et al. Effect of p63 expression on survival in oral squamous cell carcinoma. Cancer Invest. 2007;25:464-9.
http://dx.doi.org/10.1080/07357900701509387
PMid:17882659

 

25. Benard J, Douc-Rasy S, Ahomadegbe JC. TP53 family members and human cancers. Hum Mutat. 2003;21:182-91.
http://dx.doi.org/10.1002/humu.10172
PMid:12619104

 

26. Varsha B, Gharat AL, Nagamalini B, Jyothsna M, Mothkur ST, Swaminathan U. Evaluation and comparison of expression of p63 in odontogenic keratocyst, solid ameloblastoma and unicystic ameloblastoma. J Oral Maxillofac Pathol. 2014;18:223-8.
http://dx.doi.org/10.4103/0973-029X.140755
PMid:25328303 PMCid:PMC4196291

 

27. Li TJ, Browne RM, Prime SS, Paterson IC, Matthews JB. p53 expression in odontogenic keratocyst epithelium. J Oral Pathol Med. 1996;25:249-55.
http://dx.doi.org/10.1111/j.1600-0714.1996.tb01380.x

PMid:8835823

 

28. Liu L, Cui X, Sakaguchi T, Sasaki M, Suda T, Hatakeyama K. Expression of p73 in colorectal carcinoma: clinicopathological relevance. J Int Med Res. 2001;29:297-303.
http://dx.doi.org/10.1177/147323000102900406
PMid:11675903

 

29. Kademani D, Lewis JT, Lamb DH, Rallis DJ, Harrington JR. Angiogenesis and CD34 expression as a predictor of recurrence in oral squamous cell carcinoma. J Oral Maxillofac Surg. 2009;67:1800-5.
http://dx.doi.org/10.1016/j.joms.2008.06.081
PMid:19686913

30. Gadbail AR, Hande A, Chaudhary M, Nikam A, Gawande M, Patil S, et al. Tumor angiogenesis in keratocystic odontogenic tumor assessed by using CD-105 antigen. J Oral Pathol Med. 2011;40:263-9.
http://dx.doi.org/10.1111/j.1600-0714.2010.00962.x
PMid:20969632