Principe S, Dikova V, Bagán J. Salivary Cytokines in patients with Head and Neck Cancer (HNC) treated with Radiotherapy. J Clin Exp Dent. 2019;11(11):e1072-7.

 

doi:10.4317/jced.56318

http://dx.doi.org/10.4317/jced.56318

______________________________________________________________________________________________________

 

References

1. Lo Nigro C, Denaro N, Merlotti A, Merlano M. Head and neck cancer: Improving outcomes with a multidisciplinary approach. Cancer Manag Res. 2017;9:363-371.
https://doi.org/10.2147/CMAR.S115761
PMid:28860859 PMCid:PMC5571817

 

 

2. Guerra EN, Acevedo AC, Leite AF, Gozal D, Chardin H, De Luca Canto G. Diagnostic capability of salivary biomarkers in the assessment of head and neck cancer: A systematic review and meta-analysis. Oral Oncol. 2015;51:805-18.
https://doi.org/10.1016/j.oraloncology.2015.06.010
PMid:26170140

 

3. Elrefaey S, Massaro MA, Chiocca S, Chiesa F, Ansarin M. HPV in oropharyngeal cancer: the basics to know in clinical practice. Acta Otorhinolaryngol Ital. 2014;5: 299-309.

 

4. Huang SH, O'Sullivan B. Oral cancer: Current role of radiotherapy and chemotherapy. Med Oral Patol Oral Cir Bucal. 2013;2:e233-40.
https://doi.org/10.4317/medoral.18772
PMid:23385513 PMCid:PMC3613874

 

5. Citrin DE, Hitchcock YJ, Chung EJ, Frandsen J, Urick ME, Shield W, Gaffney D. Determination of cytokine protein levels in oral secretions in patients undergoing radiotherapy for head and neck malignancies. Radiat Oncol. 201226;7:64.
https://doi.org/10.1186/1748-717X-7-64
PMid:22537315 PMCid:PMC3439271

 

6. Guerra EN, Rêgo DF, Elias ST, Coletta RD, Mezzomo LA, Gozal D, et al. Diagnostic accuracy of serum biomarkers for head and neck cancer: A systematic review and meta-analysis. Crit Rev Oncol Hematol. 2016;101:93-118.
https://doi.org/10.1016/j.critrevonc.2016.03.002
PMid:26971993

 

7. Osman TA, Costea DE, Johannessen AC. The use of salivary cytokines as a screening tool for oral squamous cell carcinoma: A review of the literature. J oral Maxillofac Pathol. 2012;2:256.
https://doi.org/10.4103/0973-029X.99083
PMid:22923900 PMCid:PMC3424944

 

8. Russo N, Bellile E, Murdoch-kinch CA, Liu M. Cytokines in saliva increase in head and neck cancer patients after treatment. Oral Surgery Oral Med Oral Pathol Oral Radiol. 2016;122 483-490.e1.
https://doi.org/10.1016/j.oooo.2016.05.020
PMid:27554375 PMCid:PMC5031552

 

9. Schapher M, Wendler O, Gröschl M. Salivary cytokines in cell proliferation and cancer. Clin Chim Acta. 2011;412:1740-1748.
https://doi.org/10.1016/j.cca.2011.06.026
PMid:21736875

 

10. Rathnayake N, Akerman S, Klinge B, Lundegren N, Jansson H, Tryselius Y, Sorsa T, Gustafsson A. Salivary biomarkers for detection of systemic diseases. PloS One. 2013;8:e61356.
https://doi.org/10.1371/journal.pone.0061356
PMid:23637817 PMCid:PMC3634781

 

11. Eisbruch A, Marsh LH, Martel MK, Ship JA, Ten Haken R, Pu AT, Fraass BA, Lichter AS. Comprehensive irradiation of head and neck cancer using conformal multisegmental fields: assessment of target coverage and noninvolved tissue sparing. Int J Radiat Oncol Biol Phys. 1998;41:559-68.

https://doi.org/10.1016/S0360-3016(98)00082-0

PMid:9635702

12. Bossi P, Bergamini C, Miceli R, Cova A, Orlandi E, Resteghini C, et al. Salivary Cytokine Levels and Oral Mucositis in Head and Neck Cancer Patients Treated With Chemotherapy and Radiation Therapy. Int J Radiat Oncol Biol Phys. 2016;96:959-966.
https://doi.org/10.1016/j.ijrobp.2016.08.047
PMid:27745982

 

13. Epstein JB, Emerton S, Guglietta A, Le N. Assessment of epidermal growth factor in oral secretions of patients receiving radiation therapy for cancer. Oral Oncol. 1997;33:359-63.
https://doi.org/10.1016/S1368-8375(97)00009-2

PMID: 9415337

 

14. Epstein JB, Gorsky M, Guglietta A, Le N, Sonis ST. The correlation between epidermal growth factor levels in saliva and the severity of oral mucositis during oropharyngeal radiation therapy. Cancer. 2000;89:2258-65.

PMid: 11147596

 

15. Rhodus NL, Ho V, Miller CS, Myers S, Ondrey F. NF-κB dependent cytokine levels in saliva of patients with oral preneoplastic lesions and oral squamous cell carcinoma. Cancer Detect Prev. 2005; 29:42-45.
https://doi.org/10.1016/j.cdp.2004.10.003
PMid:15734216

 

16. Guerra ENS, Acevedo AC, Leite AF, Gozal D, Chardin H, De Luca Canto G. Diagnostic capability of salivary biomarkers in the assessment of head and neck cancer: A systematic review and meta-analysis. Oral Oncol. 2015;51:805-818.
https://doi.org/10.1016/j.oraloncology.2015.06.010
PMid:26170140

 

17. St John MA, Li Y, Zhou X, Denny P, Ho CM, Montemagno C, et al. Interleukin 6 and interleukin 8 as potential biomarkers for oral cavity and oropharyngeal squamous cell carcinoma. Arch Otolaryngol Head Neck Surg. 2004;130:929-35.
https://doi.org/10.1001/archotol.130.8.929
PMid:15313862

 

18. Juretić M, Cerović R, Belušić-Gobić M, Brekalo Pršo I, Kqiku L, Špalj S, Pezelj-Ribarić S. Salivary levels of TNF-α and IL-6 in patients with oral premalignant and malignant lesions. Folia Biol (Praha). 2013;59:99-102.

PMid: 23746176

 

19. SahebJamee M, Eslami M, AtarbashiMoghadam F, Sarafnejad A. Salivary concentration of TNFalpha, IL1 alpha, IL6, and IL8 in oral squamous cell carcinoma. Med Oral Patol Oral Cir Bucal. 2008;13:E292-5.

PMid:18449112

 

20. Sahibzada HA, Khurshid Z, Khan RS, Naseem M, Siddique KM, Mali M, et al. Salivary IL-8, IL-6 and TNF-α as Potential Diagnostic Biomarkers for Oral Cancer. Diagnostics (Basel). 2017;7.pii: E21.
https://doi.org/10.3390/diagnostics7020021
PMid:28397778 PMCid:PMC5489941