Aragón-Niño I, Cuesta-Urquía C, González-Martín-Moro J, Morán-Soto MJ, Pozo-Kreilinger JJ, Pampín-Martinez MM, del Castillo-Pardo-de Vera JL, Cebrián-Carretero JL. HPV infection in oral cancer, our experience: prevalence, clinical implications, and current vaccination program in Spain. J Clin Exp Dent. 2023;15(7):e584-9.

doi:10.4317/jced.60514

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References

1. Syrjänen K, Syrjänen S, Lamberg M, Pyrhönen S, Nuutinen J. Morphological and immunohistochemical evidence suggesting human papillomavirus (HPV) involvement in oral squamous cell carcinogenesis. Int J Oral Surg.1983;12:418-24. https://doi.org/10.1016/S0300-9785(83)80033-7 PMid:6325356

2. Seijas-Tamayo R, Fernández-Mateos J, Adansa Klain JC, Mesía R, Pastor Borgoñón M, Pérez-Ruiz E, et al. Epidemiological characteristics of a Spanish cohort of patients diagnosed with squamous cell carcinoma of head and neck: distribution of risk factors by tumor location. Clinical and Translational Oncology. 2016;18:1114-22. https://doi.org/10.1007/s12094-016-1493-1 PMid:27112939

3. Chaturvedi AK, Engels EA, Anderson WF, Gillison ML. Incidence trends for human papillomavirus-related and -unrelated oral squamous cell carcinomas in the United States. Journal of Clinical Oncology. 2008;26:612-9. https://doi.org/10.1200/JCO.2007.14.1713 PMid:18235120

4. Villagómez-Ortíz VJ, Paz-Delgadillo DE, Marino-Martínez I, Ceseñas-Falcón LÁ, Sandoval-de la Fuente A, Reyes-Escobedo A. Prevalencia de infección por virus del papiloma humano en carcinoma espinocelular de cavidad oral, orofaringe y laringe. Cir Cir. 2016;84:363-8. https://doi.org/10.1016/j.circir.2016.01.006 PMid:27032466

5. Nogues JC, Fassas S, Mulcahy C, Zapanta PE. Human papillomavirus-associated head and neck cancer. Journal of the American Board of Family Medicine. American Board of Family Medicine. 2021;34:832. https://doi.org/10.3122/jabfm.2021.04.200588

6. Tumban E. A current update on human papillomavirus-associated head and neck cancers. Viruses. MDPI AG; 2019;11. https://doi.org/10.3390/v11100922 PMid:31600915 PMCid:PMC6833051

7. Sabatini ME, Chiocca S. Human papillomavirus as a driver of head and neck cancers. British Journal of Cancer. Springer Nature. 2020;122:306-14. https://doi.org/10.1038/s41416-019-0602-7 PMid:31708575 PMCid:PMC7000688

8. Melo BA de C, Vilar LG, Oliveira NR de, Lima PO de, Pinheiro M de B, Domingueti CP, et al. Human papillomavirus infection and oral squamous cell carcinoma - a systematic review. Brazilian Journal of Otorhinolaryngology. Elsevier Editora Ltda. 2021;87:346-52. https://doi.org/10.1016/j.bjorl.2020.10.017 PMid:33339760 PMCid:PMC9422740

9. Chaitanya N, Allam N, Gandhi Babu D, Waghray S, Badam R, Lavanya R. Systematic meta-analysis on association of human papilloma virus and oral cancer. J Cancer Res Ther. 2016;12:969-74. https://doi.org/10.4103/0973-1482.179098 PMid:27461683

10. Kansy K, Thiele O, Freier K. The role of human papillomavirus in oral squamous cell carcinoma: Myth and reality. Oral Maxillofac Surg. 2014;18:165-72. https://doi.org/10.1007/s10006-012-0383-0 PMid:23242943

11. Narisawa-Saito M, Kiyono T. Basic mechanisms of high-risk human papillomavirus-induced carcinogenesis: Roles of E6 and E7 proteins. Cancer Science. 2007;98:1505-11. https://doi.org/10.1111/j.1349-7006.2007.00546.x PMid:17645777

12. Shyamsundar V, Thangaraj SV, Krishnamurthy A, Vimal S, Kesavan P, Babu A, et al. Exome Sequencing with Validations and Expression of p16/CDKN2A Shows no Association with HPV in Oral Cancers. Asian Pacific Journal of Cancer Prevention. 2022;23:191-200. https://doi.org/10.31557/APJCP.2022.23.1.191 PMid:35092388 PMCid:PMC9258643

13. Ndiaye C, Mena M, Alemany L, Arbyn M, Castellsagué X, Laporte L, et al. HPV DNA, E6/E7 mRNA, and p16INK4a detection in head and neck cancers: a systematic review and meta-analysis. Lancet Oncol. 2014;15:1319-31. https://doi.org/10.1016/S1470-2045(14)70471-1 PMid:25439690

14. Santacroce L, di Cosola M, Bottalico L, Topi S, Charitos IA, Ballini A, et al. Focus on hpv infection and the molecular mechanisms of oral carcinogenesis. Viruses. MDPI AG. 2021;13. https://doi.org/10.3390/v13040559 PMid:33810374 PMCid:PMC8067023

15. Ndiaye C, Mena M, Alemany L, Arbyn M, Castellsagué X, Laporte L, et al. HPV DNA, E6/E7 mRNA, and p16INK4a detection in head and neck cancers: A systematic review and meta-analysis. Lancet Oncol. 2014;15:1319-31. https://doi.org/10.1016/S1470-2045(14)70471-1 PMid:25439690

16. Lewis JS, Beadle B, Bishop JA, Chernock RD, Colasacco C, Lacchetti C, et al. Human papillomavirus testing in head and neck carcinomas guideline from the college of American pathologists. Arch Pathol Lab Med. 2018;142:559-97. https://doi.org/10.5858/arpa.2017-0286-CP PMid:29251996

17. Burd EM. Human papillomavirus laboratory testing: The changing paradigm. Clin Microbiol Rev. 2016;29:291-319. https://doi.org/10.1128/CMR.00013-15 PMid:26912568 PMCid:PMC4786885

18. Valls-Ontañón A, Hernández-Losa J, Somoza Lopez de Haro R, Bellosillo-Paricio B, Ramón y Cajal S, Bescós-Atín C, et al. Impact of human papilloma virus in patients with oral and oropharyngeal squamous cell carcinomas. Med Clin (Barc). 2019;152:174-80. https://doi.org/10.1016/j.medcle.2019.01.005

19. Gomez-Armayones S, Chimenos-Küstner E, Marí A, Tous S, Penin R, Clavero O, et al. Human papillomavirus in premalignant oral lesions: No evidence of association in a Spanish cohort. PLoS One. 2019;14. https://doi.org/10.1371/journal.pone.0210070 PMid:30650110 PMCid:PMC6335078

20. Fiorillo L, Cervino G, Surace G, de Stefano R, Laino L, D'Amico C, et al. Human Papilloma Virus: Current Knowledge and Focus on Oral Health. BioMed Research International. Hindawi Limited. 2021;2021. https://doi.org/10.1155/2021/6631757 PMid:33623784 PMCid:PMC7875628

21. Giraldi L, Collatuzzo G, Hashim D, Franceschi S, Herrero R, Chen C, et al. Infection with Human Papilloma Virus (HPV) and risk of subsites within the oral cancer. Cancer Epidemiol. 2021;75. https://doi.org/10.1016/j.canep.2021.102020 PMid:34509873

22. van der Waal I. Oral potentially malignant disorders: Is malignant transformation predictable and preventable? Med Oral Patol Oral Cir Bucal. 2014;19. https://doi.org/10.4317/medoral.20205 PMid:24905952 PMCid:PMC4119315

23. Lafaurie GI, Perdomo SJ, Buenahora MR, Amaya S, Díaz-Báez D. Human papilloma virus: An etiological and prognostic factor for oral cancer? J Investig Clin Dent. 2018;9:e12313. https://doi.org/10.1111/jicd.12313 PMid:29322686

24. Agrawal Y, Koch WM, Xiao W, Westra WH, Trivett AL, Symer DE, et al. Oral human papillomavirus infection before and after treatment for human papillomavirus 16-positive and human papillomavirus 16-negative head and neck squamous cell carcinoma. Clinical Cancer Research. 2008;14:7143-50. https://doi.org/10.1158/1078-0432.CCR-08-0498 PMCid:PMC2598779

25. Herrero R, Castellsagué X, Pawlita M, Lissowska J, Kee F, Balaram P, et al. Human papillomavirus and oral cancer: The international agency for research on cancer multicenter study. J Natl Cancer Inst. 2003;95:1772-83. https://doi.org/10.1093/jnci/djg107 PMid:14652239

26. Yete S, D'Souza W, Saranath D. High-Risk Human Papillomavirus in Oral Cancer: Clinical Implications. Oncology (Switzerland). S. Karger AG. 2018;94:133-41. https://doi.org/10.1159/000485322 PMid:29241220

27. Christianto S, Li KY, Huang TH, Su YX. The Prognostic Value of Human Papilloma Virus Infection in Oral Cavity Squamous Cell Carcinoma: A Meta-Analysis. Laryngoscope. John Wiley and Sons Inc. 2022;132:1760-70. https://doi.org/10.1002/lary.29996 PMid:34953144

28. Lee LA, Huang CG, Liao CT, Lee LY, Hsueh C, Chen TC, et al. Human papillomavirus-16 infection in advanced oral cavity cancer patients is related to an increased risk of distant metastases and poor survival. PLoS One. 2012;7. https://doi.org/10.1371/journal.pone.0040767 PMid:22808258 PMCid:PMC3395633

29. Lee LA, Huang CG, Liao CT, Lee LY, Hsueh C, Chen TC, et al. Human papillomavirus-16 infection in advanced oral cavity cancer patients is related to an increased risk of distant metastases and poor survival. PLoS One. 2012;7. https://doi.org/10.1371/journal.pone.0040767 PMid:22808258 PMCid:PMC3395633

30. Arbyn M, Xu L, Simoens C, Martin-Hirsch PPL. Prophylactic vaccination against human papillomaviruses to prevent cervical cancer and its precursors. Cochrane Database of Systematic Reviews. John Wiley and Sons Ltd. 2018;2018. https://doi.org/10.1002/14651858.CD009069.pub3 PMid:29740819 PMCid:PMC6494566

31. Abel MK, Mann AK, Sonawane K, Kapp DS, Deshmukh AA, Chan JK. Prevalence of Oral Human Papillomavirus Infection by Number of Vaccine Doses Among US Adults. JNCI Cancer Spectr. 2021;5. https://doi.org/10.1093/jncics/pkab086 PMCid:PMC8713009

32. Choi SE, Choudhary A, Huang J, Sonis S, Giuliano AR, Villa A. Increasing HPV vaccination coverage to prevent oropharyngeal cancer: A cost-effectiveness analysis. Tumour Virus Res. 2022;13. https://doi.org/10.1016/j.tvr.2021.200234 PMid:34974194 PMCid:PMC8749055