Ortiz-Sáez B, Aguilella-Traver M, Hernández-Pando C, Martínez-Salmerón EM, Muñoz-Barrio JE, Gómez-Moreno G. Is xylitol effective in the prevention of dental caries? A systematic review. J Clin Exp Dent. 2024;16(10):e1307-15.

doi:10.4317/jced.62008

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References

1. ALHumaid J, Bamashmous M. Meta-analysis on the Effectiveness of Xylitol in Caries Prevention. J Int Soc Prev Community Dent. 2022;12:133-8. https://doi.org/10.4103/jispcd.JISPCD_164_21

2. Jayadevan A, Chakravarthy D, Padmaraj SN, VijayaRaja S, Bal L, Dimple N. Dental Caries and Sugar Substitutes: A Review. IOSR J Dent Med Sci. 2019;18:13-23.

3. de Oliveira GGC, Freires DMT, de Oliveira SG, de Mattos AL, Weyne SC, Hirata R. Antibacterial and anticariogenic properties of xylitol a literature review. Rev Bras Odontol. 2018;75:e960. https://doi.org/10.18363/rbo.v75.2018.e960

4. Yazdani R, Albujeer ANH, Rahnama E, Kharazifard MJ. Effect of Xylitol on Salivary Streptococcus Mutans: A Systematic Review and Meta-analysis. J Contemp Med Sci. 2019.26;5:64-70. https://doi.org/10.22317/jcms.v5i2.582

5. Nayak PA, Nayak UA, Khandelwal V. The effect of xylitol on dental caries and oral flora. Clin Cosmet Investig Dent. 2014;6:89-94. https://doi.org/10.2147/CCIDE.S55761

6. Ahmed M, Fuad A, Shukry GM, Labib ML. Anti-Cariogenic effect of Five-Carbon Sugar: Xylitol. J Dent Salud Bucal. 2017;3:081.

7. Janket SJ, Benwait J, Isaac P, Ackerson LK, Meurman JH. Oral and Systemic Effects of Xylitol Consumption. Caries Res. 2019;53:491-501. https://doi.org/10.1159/000499194

8. Gasmi Benahmed A, Gasmi A, Arshad M, Shanaida M, Lysiuk R, Peana M, et al. Health benefits of xylitol. Appl Microbiol Biotechnol. 2020;104:7225-37. https://doi.org/10.1007/s00253-020-10708-7

(9) Young-Eun L, Ji-Hye K, Min-Jeong C, Keun-Bae S, Youn-Hee C. Effect of xylitol on dental caries prevention: a literature review. J Korean Soc Dent Hyg. 2019;19:449-65. https://doi.org/10.13065/jksdh.20190041

10. Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;372:n71. https://doi.org/10.1136/bmj.n71

11. Saaiq M, Ashraf B. Modifying "Pico" Question into "Picos" Model for More Robust and Reproducible Presentation of the Methodology Employed in A Scientific Study. World J Plast Surg. 2017;6:390-2.

12. Takeuchi K, Asakawa M, Hashiba T, Takeshita T, Saeki Y, Yamashita Y. Effects of xylitol-containing chewing gum on the oral microbiota. J Oral Sci. 2018;60(4):588-94. https://doi.org/10.2334/josnusd.17-0446

13. Jain RL, Tandon S, Rai TS, Mathur R, Soni KK, Rawat M. A Comparative Evaluation of Xylitol Chewing Gum and a Combination of IgY + Xylitol Chewable Tablet on Salivary Streptococcus mutans Count in Children: A Double-blind Randomized Controlled Trial. Int J Clin Pediatr Dent 2022;15:S212-20. https://doi.org/10.5005/jp-journals-10005-2162

14. Masoud MI, Allarakia R, Alamoudi NM, Nalliah R, Allareddy V. Long-term clinical and bacterial effects of xylitol on patients with fixed orthodontic appliances. Prog Orthod. 2015;16:35. https://doi.org/10.1186/s40510-015-0103-z

15. Akgül Ö, Topaloğlu Ak A, Zorlu S, Öner Özdaş D, Uslu M, Çayirgan D. Effects of short-term xylitol chewing gum on pro-inflammatory cytokines and Streptococcus mutans: A randomised, placebo-controlled trial. Int J Clin Pract. 2020;74:e13623. https://doi.org/10.1111/ijcp.13623

16. Kayalvizhi G, Nivedha D, Sajeev R, Prathima GS, Suganya M, Ramesh V. Evaluating the Efficacy of Xylitol Wipes on Cariogenic Bacteria in 19- to 35-month-old Children: A Double-blind Randomized Controlled Trial. Int J Clin Pediatr Dent. 2018;11:13-7. https://doi.org/10.5005/jp-journals-10005-1476

17. Chavan S, Lakashminarayan N, Kemparaj U. Effect of Chewing Xylitol Containing and Herbal Chewing Gums on Salivary Mutans Streptococcus Count among School Children. Int J Prev Med. 2015;6:44. https://doi.org/10.4103/2008-7802.157543

18. Kosara S, Çokakoğlu S, Kaleli İ. Effects of xylitol impregnated toothbrushes on periodontal status and microbial flora in orthodontic patients. Angle Orthod. 2020;90(6):837-43. https://doi.org/10.2319/022420-125.1

19.Bader JD, Vollmer WM, Shugars DA, Gilbert GH, Amaechi BT, Brown JP, et al. Results from the Xylitol for Adult Caries Trial (X-ACT). J Am Dent Assoc. 2013;144:21-30. https://doi.org/10.14219/jada.archive.2013.0010

20. Mäkinen KK, Järvinen KL, Anttila CH, Luntamo LM, Vahlberg T. Topical xylitol administration by parents for the promotion of oral health in infants: a caries prevention experiment at a Finnish Public Health Centre. Int Dent J. 2013;63(4):210-24. https://doi.org/10.1111/idj.12038