Moreira MS,
Mota ME, Ariga SKK, Jaguar GC, Marques MM. Mesenchymal stem cell therapies
evidence in the treatment of irradiated salivary glands: A scoping review. J
Clin Exp Dent. 2024;16(12):e1547-54.
doi:10.4317/jced.62242
https://doi.org/10.4317/jced.62242
_____
References
1.
Mese H, Matsuo R. Salivary secretion, taste and hyposalivation. J Oral
Rehabil. 2007;34:711-723. |
|
|
|
2.
Villa A, Wolff A, Narayana N, Dawes C, Aframian DJ, Pedersen AML, et al.
World Workshop on Oral Medicine VI: a systematic review of medication-induced
salivary gland dysfunction. Oral Dis. 2016;2:365-382. |
|
|
|
3.
Chansaenroj A, Yodmuang S, Ferreira JN. Trends in Salivary Gland Tissue
Engineering: From Stem Cells to Secretome and Organoid Bioprinting. Tissue
Eng Part B Rev. 2021;27:155-165. |
|
|
|
4.
Emmerson E, May AJ, Berthoin L, Cruz-Pacheco N, Nathan S, Mattingly AJ, et
al. Salivary glands regenerate after radiation injury through SOX2-mediated
secretory cell replacement. EMBO Mol Med. 2018;10:e8051. |
|
|
|
5.
Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al.
Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality
Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021;71:209-249. |
|
|
|
6.
Acauan MD, Figueiredo MAZ, Cherubini K, Gomes APN, Salum FG.
Radiotherapy-induced salivary dysfunction: Structural changes, pathogenetic
mechanisms and therapies. Arch Oral Biol. 2015;60:1802-1810. |
|
|
|
7.
Gil-Montoya J, Silvestre F, Barrios R, Silvestre-Rangil J. Treatment of
xerostomia and hyposalivation in the elderly: A systematic review. Med Oral
Patol Oral Cir Bucal. 2016;1:21, 355-66. |
|
|
|
8.
Coelho CPS, Melo JLMA, Nunes FPS, Guimarães MCM, Heller D, Grisi DC, et al.
Clinical management of salivary gland hypofunction in patients with head and
neck cancer: a scoping review of physical salivary stimulation methods. Oral
Surg Oral Med Oral Pathol Oral Radiol. 2023;136:442-458. |
|
|
|
9.
Su X, Liu Y, Bakkar M, ElKasthy O, El-Hakim M, Seuntjens J, et al. Labial
Stem Cell Extract Mitigates Injury to Irradiated Salivary Glands. J Dent Res.
2020; 99:293-301. |
|
|
|
10.
Lim JY, Ra JC, Shin IS, Jang YH, AN HY, Choi JS, et al. Systemic
Transplantation of Human Adipose Tissue-Derived Mesenchymal Stem Cells for
the Regeneration of Irradiation-Induced Salivary Gland Damage. PLoS One.
2013;8:e71167. |
|
|
|
11.
Chou Y, Alfarafisa NM, Ikezawa M, Khairani AF. Progress in the development of
stem cell-derived cell-free therapies for sking aging. Clin Cosmet Investig
Dermatol. 2023;22:3383-3406. |
|
|
|
12.
Arksey H, O'Malley L. Scoping studies: towards a methodological framework.
Int J Soc Res Methodol. 2005;8:19-32. |
|
|
|
13.
Peters MD, Godfrey CM, Khalil H, McInerney P, Parker D, Soares CB. Guidance
for conducting systematic scoping reviews. Int J Evid Based Healthc.
2015;13:141-6. |
|
|
|
14.
Tricco AC, Lillie E, Zarin W, O'Brien KK, Colquhoun H, Levac D, et al. PRISMA
Extension for Scoping Reviews (PRISMA-ScR): Checklist and Explanation. Ann
Intern Med. 2018;169:467-473. |
|
|
|
15.
Sumita Y, Liu Y, Khalili S, Maria OM, Xia D, Key S, et al. Bone
marrow-derived cells rescue salivary gland function in mice with head and neck
irradiation. Int J Biochem Cell Biol. 2011;43:80-87. |
|
|
|
16.
Wang Z, Xing H, Hu H, Dai T, Wang Y, Li Z, et al. Intraglandular
transplantation of adipose derived stem cells combined with platelet rich
fibrin extract for the treatment of irradiation induced salivary gland
damage. Exp Ther Med. 2018;15:795-805. |
|
|
|
17.
Choi J, An H, Shin H, Kim Y, Lim J. Enhanced tissue remodelling efficacy of
adipose-derived mesenchymal stem cells using injectable matrices in
radiation-damaged salivary gland model. J Tissue Eng Regen Med.
2018;12:e:695-706. |
|
|
|
18.
Pringle S, Maimets M, van der Zwaag M, Stokman MA, Gosliga DV, Zwart E, et
al. Human Salivary Gland Stem Cells Functionally Restore Radiation Damaged
Salivary Glands. Stem Cells. 2016;34:640-652. |
|
|
|
19.
Mohamed NH, Shawkat S, Moussa MS, Ahmed N. Regeneration potential of bone
marrow derived mesenchymal stem cells and platelet rich plasma (PRP) on
irradiation-induced damage of submandibular salivary gland in albino rats.
Tissue Cell. 2022;76:101780. |
|
|
|
20.
Wang Z, Ju Z, He L, Li Z, Liu Y, Liu B. Intraglandular Transplantation of
Adipose-Derived Stem Cells for the Alleviation of Irradiation-Induced Parotid
Gland Damage in Miniature Pigs. Journal of Oral and Maxillofacial Surgery.
2017;75:1784-1790. |
|
|
|
21.
Zayed HM, Din NHKE, Abu-Seida AM, Zeid AAA, Ezzatt OM. Gingival-derived
mesenchymal stem cell therapy regenerated the radiated salivary glands:
functional and histological evidence in murine model. Stem Cell Res Ther.
2024;26:46. |
|
|
|
22.
An HY, Shin HS, Choi JS, Kim HJ, Lim JY, Kim YM. Adipose Mesenchymal Stem
Cell Secretome Modulated in Hypoxia for Remodeling of Radiation-Induced
Salivary Gland Damage. PLoS One. 2015;10:e0141862. |
|
|
|
23.
Dong J, Sakai K, Koma Y, Watanabe J, Liu K, Maruayama H, et al. Dental pulp
stem cell-derived small extracellular vesicle in irradiation-induced
senescence. Biochem Biophys Res Commun. 2021;20:575:28-35. |
|
|
|
24.
Kano F, Hashimoto N, Liu Y, Xia L, Nishihar T, Oki W, et al. Therapeutic
benefits of factors derived from stem cells from human exfoliated deciduous
teeth for radiation-induced mouse xerostomia. Sci Rep. 2023;15:2706. |
|
|
|
25.
Xiao X, Zhang N, Long Y, Huang G. Repair mechanism of radiation-induced
salivary gland injury by hypoxia-pretreateds human urine-derived stem cell
exosomes. Oral Dis. 2022;22. |
|
|
|
26.
Steenbakkers RJHM, van Rijn-Dekker MI, Stokman MA, Kierkels RGJ, Schaaf AVD,
et al. Parotid Gland Stem Cell Sparing Radiation Therapy for Patients With
Head and Neck Cancer: A Double-Blind Randomized Controlled Trial.
International Journal of Radiation Oncology Biology Physics.
2022;112:306-316. |
|
|
|
27.
Ullah I, Subbarao RB, Rho GJ. Human mesenchymal stem cells - current trends
and future prospective. Biosci Rep. 2015;35:e:00191. |
|
|
|
28.
Mazini L, Rochette L, Admou B, Amal S, Malka G. Hopes and Limits of
Adipose-Derived Stem Cells (ADSCs) and Mesenchymal Stem Cells (MSCs) in Wound
Healing. Int J Mol Sci. 2020;21:1306. |
|
|
|
29.
Silva FS, Ramos RN, Almeida DC, Bassi EJ, Gonzales RP,Miyagi SPH, et al. Mesenchymal
Stem Cells Derived from Human Exfoliated Deciduous Teeth (SHEDs) Induce
Immune Modulatory Profile in Monocyte-Derived Dendritic Cells. PLoS One.
2014;9:e98050. |
|
|
|
30.
La Noce M, Paino F, Spina A, Naddeo P, Montella R, Desiderio V, et al. Dental
pulp stem cells: State of the art and suggestions for a true translation of
research into therapy. J Dent. 2014;42:761-768. |
|
|
|
31.
Ding G, Niu J, Liu Y. Dental pulp stem cells suppress the proliferation of
lymphocytes via transforming growth factor-β1. Hum Cell. 2015;28:81-90. |
|
|
|
32.
Lynggaard CD, Grønhøj C, Christensen R, Fischer-Nielsen A, Melchiors J, et
al. Intraglandular Off-the-Shelf Allogeneic Mesenchymal Stem Cell Treatment
in Patients with Radiation-Induced Xerostomia: A Safety Study (MESRIX-II).
Stem Cells Transl Med. 2022;11,478-489. |
|
|
|
33.
Kumar L P, Kandoi S, Misra R, Vijayalakshmi S, Rajagopal K, Verma RS. The
mesenchymal stem cell secretome: A new paradigm towards cell-free therapeutic
mode in regenerative medicine. Cytokine Growth Factor Rev. 2019;46:1-9. |
|
|
|
34.
Tillner F, Thute P, Bütof R, Krause M, Enghardt W. Pre-clinical research in
small animals using radiotherapy technology - a bidirectional translational
approach. Z Med Phys. 2014;24:335-351. |
|
|
|
35.
Juvkam IS, Zlygosteva O, Arous D, Galtung HK, Malinen E, Soland TM, et al. A
preclinical model to investigate normal tissue damage following fractionated
radiotherapy to the head and neck. J Radiat Res. 2023;64, 44-52. |
|
|
|
36.
Grønhøj C, Jensen DH, Vester-Glowinski P, Jensen SB, Bardow A, Oliveri RS, et
al. Safety and Efficacy of Mesenchymal Stem Cells for Radiation-Induced
Xerostomia: A Randomized, Placebo-Controlled Phase 1/2 Trial (MESRIX).
International Journal of Radiation Oncology Biology Physics.
2018;101:581-592. |
|
|
|
37.
Tran SD, Liu Y, Xia D, Maria OM, Khalili S, Wang RWJ, et al. Paracrine
Effects of Bone Marrow Soup Restore Organ Function, Regeneration, and Repair
in Salivary Glands Damaged by Irradiation. PLoS One. 2013;8:e61632. |
|
|
|
38.
Su X, Upadhyay A, Tran SD, Lin Z. Cell-Free Therapies: The Use of Cell
Extracts to Mitigate Irradiation-Injured Salivary Glands. Biology (Basel).
2023;12:305. |
|
|
|
39.
Zhou C, Zhang B, Yang Y, Jiang Q, Li T, Gong J, Tang H, Zhang Q. Stem
cell-derived exosomes: emerging therapeutic opportunities for wound healing.
Stem Cell Res Ther. 2023;14:107. |
|
|
|
40.
Wolff A, Koray M, Campisi G, Strietzel FP, Lafaurie GI, Beiski BZ, et al.
Electrostimulation of the lingual nerve by an intraoral device may lead to
salivary gland regeneration: A case series study. Med Oral Patol Oral Cir
Bucal. 2019;1:e552-559. |
|
|
|
41.
Ferreira JNA, Zheng C, Lombaert IMA, Goldsmith CM, Cotrim AP, Symonds JM, et
al. Neurturin Gene Therapy Protects Parasympathetic Function to Prevent
Irradiation-Induced Murine Salivary Gland Hypofunction. Mol Ther Methods Clin
Dev. 2018;9:172-180. |
|
|
|
42.
Tatsuishi Y, Hirota M, Kishi T, Adachi M, Fukui T, Mitsudo K, et al. Human
salivary gland stem/progenitor cells remain dormant even after irradiation.
Int J Mol Med. 2009;24:361-6. |
|
|
|
43.
Tsutsui TW. Dental Pulp Stem Cells: Advances to Applications. Stem Cells
Cloning, 2020;13:33-42. |
|
|
|
44.
Zhang S, Thiebes AL, Kreimendahl F, Ruetten S, Buhl EM, Wolf M, et al.
Extracellular Vesicles-Loaded Fibrin Gel Supports Rapid Neovascularization
for Dental Pulp Regeneration. Int J Mol Sci. 2020;21:4226. |
|
|
|
45.
Cui M, Wu W, Li Q, Qi G, Liu X, Bai J, et al. Unlocking the Potential of
Human-Induced Pluripotent Stem Cells: Cellular Responses and Secretome
Profiles in Peptide Hydrogel 3D Culture. Cells. 2024;13:143. |
|
|
|
46.
Sears V, Danaoui Y, Ghosh G. Impact of mesenchymal stem cell-secretome-loaded
hydrogel on proliferative and migratory activities of hyperglycemic
fibroblasts. Mater Today Commun. 2021;27:102285. |
|
|
|
47.
Doshi RB, Vakil D, Molley TG, Islam MS, Kilian KA, Cunningham C, et al.
Mesenchymal stem cell-secretome Iaden photopolymerizable hydrogels for wound
healing. J Biomed Mater Res. 2024;112(9):1484-1493. PMid:38487991 |