De la Barrera-Núñez MC, Yáñez-Vico RM, Batista-Cruzado A, Heurtebise-Saavedra JM, Castillo-de Oyagüe R, Torres-Lagares D. Prospective double-blind clinical trial
evaluating the effectiveness of bromelain in the
third molar extraction postoperative period. Med Oral Patol Oral Cir Bucal. 2014 Mar 1;19
(2):e157-62.
doi:10.4317/medoral.19105
http://dx.doi.org/doi:10.4317/medoral.19105
1. Onken JE, Greer PK, Calingaert
B, Hale LP. Bromelain treatment decreases secretion
of pro-inflammatory cytokines and chemokines by
colon biopsies in vitro. ClinImmunol. 2008;126:345-52. |
|
|
|
2. Hale
LP, Chichlowski M, Trinh CT, Greer PK. Dietary
supplementation with fresh pineapple juice decreases inflammation and colonic
neoplasia in IL-10-deficient mice with colitis. Inflamm Bowel Dis. 2010;16:2012-21. |
|
|
|
3. Aiyegbusi
AI, Duru FI, Anunobi CC, Noronha CC, Okanlawon AO. Bromelain in the early phase of
healing in acute crush Achilles tendon injury.Phytother
Res. 2011;25:49-52. |
|
|
|
4. Brien
S, Lewith G, Walker A, Hicks SM, Middleton D. Bromelain as a Treatment for Osteoarthritis: a Review of Clinical
Studies. Evid Based Complement Alternat
Med. 2004;1:251-7. |
|
|
|
5. MacKay
D, Miller AL. Nutritional support for wound healing. Altern
Med Rev. 2003;8:359-77. |
|
|
|
6. Maurer
HR. Bromelain: biochemistry, pharmacology and
medical use. Cell Mol Life Sci. 2001;58:1234-45. |
|
|
|
7. TaussigSJ. The mechanism of the physiological action of bromelain. Med Hypotheses.
1980;6:99-104. |
|
|
|
8. Gaspani L, Limiroli E, Ferrario P, Bianchi M. In vivo and in vitro effects of bromelain on PGE2 and SP concentrations in the
inflammatory exudate in rats. Pharmacology.
2002;65:83-86. |
|
|
|
9. McGrath
C, Comfort MB, Lo EC, Luo Y. Changes in life
quality following third molar surgery-the immediate postoperative period. Br Dent J. 2003;194:265-8 |
|
|
|
10. Oginni FO, Ugboko VI, Assam E, Ogunbodede EO. Postoperative complaints following
impacted mandibular third molar surgery in Ile-Ife,
Nigeria. SADJ. 2002;57:264-8. |
|
|
|
11. Kirtiloğlu T, Bulut E, Sümer M, Cengiz I. Comparison
of 2 flap designs in the periodontal healing of second molars after fully
impacted mandibular third molar extractions. J Oral Maxillofac Surg.
2007;65:2206-10. |
|
|
|
12. Kim HR, Choi
BH, Engelke W, Serrano D, Xuan
F, Mo DY. A
comparative study on the extractions of partially impacted mandibular third molars with or without a buccal flap: a prospective study. J Oral MaxillofacSurg. 2011; 69:966-70. |
|
|
|
13. Freudlsperger C, Deiss T, Bodem J, Engel M, Hoffmann J. Influence of lower third
molar anatomic position on postoperative inflammatory complications. J Oral Maxillofac Surg.
2012;70:1280-5. |
|
|
|
14. Goyal M, Marya K, Jhamb A, Chawla S, Sonoo PR, Singh V, et al. Comparative evaluation of
surgical outcome after removal of impacted mandibular
third molars using a Piezotome or a conventional handpiece: a prospective study. Br J Oral Maxillofac Surg. 2012 ;50:556-61. |
|
|
|
15. Barone A, Marconcini S, Giacomelli L, Rispoli L, Calvo JL, Covani U. A randomized
clinical evaluation of ultrasound bone surgery versus traditional rotary
instruments in lower third molar extraction. J
Oral Maxillofac Surg.
2010;68:330-6. |
|
|
|
16. Osunde OD, Saheeb BD, Adebola RA. Comparative study of effect of single and
multiple suture techniques on inflammatory complications after third molar surgery.J Oral Maxillofac Surg.
2011;69:971-6. |
|
|
|
17. Sierra
Rebolledo A, Delgado Molina E, BeriniAytís
L, Gay Escoda C. Comparative study of the
anesthetic efficacy of 4% articaine versus 2% lidocaine in inferior alveolar nerve block during
surgical extraction of impacted lower third molars. Med Oral
Patol Oral Cir Bucal. 2007;12:E139-44. |
|
|
|
18. Bjørnsson GA, Haanaes HR, Skoglund LA. A randomized, double-blind crossover trial
of paracetamol 1000 mg four times daily vs ibuprofen 600 mg: effect on swelling and other
postoperative events after third molar surgery. Br J ClinPharmacol. 2003;55:405-12. |
|
|
|
19. Koerner KR. The removal of impacted third molars.Principles and procedures. Dent Clin North Am. 1994;38:255-78. |
|
|
|
20. Scott
J, Huskisson EC. Graphic representation of pain.Pain. 1976;2:175-84. |
|
|
|
21. Ossovskaya VS, Bunnet NW.
Protease-activated receptors: contribution to physiology and disease Physiol Rev 2004;84:579-621. |
|
|
|
22. Smyth
RD, Moss JN, Brennan JC. Biochemical studies on the resolution of experimental
inflammation in animals treated with bromelaínExp
Med Surg 10967;25:229-235. |
|
|
|
23. Cirelli MG. Clinical experience with bromelain
in proteolitic enzyme therapy of inflammation and
edema Med times 1964;92:919-922. |
|
|
|
24. Hotz G, Frank T, Zöller J, Wiebelt H. Antiphlogistic
effect of bromelaine following third molar removal.
DtschZahnarztl Z. 1989;44:830-2. |
|
|
|
25. Inchingolo
F, Tatullo M, Marrelli M,
Inchingolo AM, Picciariello
V, Inchingolo AD, et al. Clinical trial with bromelain
in third molar exodontia. Eur
Rev Med Pharmacol Sci. 2010;14:771-4. |
|
|
|
26. Gläser D, Hilberg T. The
influence of bromelain on platelet count and
platelet activity in vitro.Platelets. 2006;17:37-41. |
|
|