Guzeldemir-Akcakanat E, Gurgan CA. Systemic moxifloxacin vs amoxicillin/metronidazole adjunct to non-surgical
treatment in generalized aggressive periodontitis. Med Oral Patol Oral Cir Bucal. 2015 Jul 1;20 (4):e441-9.
doi:10.4317/medoral.20552
http://dx.doi.org/doi:10.4317/medoral.20552
1. Haffajee AD, Socransky SS, Gunsolley JC. Systemic anti-infective periodontal therapy.
A systematic review. Ann Periodontol. 2003;8:115-81. |
|
|
|
2.
Herrera D, Sanz M, Jepsen S, Needleman
I, Roldan S. A systema-tic review
on the effect of systemic antimicrobials as an adjunct to scaling
and root planing in
periodontitis patients. J Clin
Periodontol. 2002;29 Suppl
3:136-59. |
|
|
|
3.
van Winkelhoff AJ, Rams
TE, Slots J. Systemic antibiotic
therapy in periodontics. Periodontol 2000. 1996;10:45-78. |
|
|
|
4. Mestnik MJ, Feres M, Figueiredo LC, Duarte PM, Lira EA, Faveri
M. Short-term benefits of
the adjunctive use of metronidazole plus amoxicillin
in the microbial profile and in the clinical parameters of subjects with generalized aggressive
periodontitis. J Clin Periodontol.
2010;37:353-65. |
|
|
|
5.
Slots J, Research, Science
and Therapy Committee. Systemic antibiotics in periodontics. J Periodontol.
2004;75:1553-65. |
|
|
|
6.
Herrera D, Alonso B, Leon R, Roldan S, Sanz M. Antimicrobial therapy in
periodontitis: the use of systemic
antimicrobials against the subgingival biofilm. J Clin Periodontol. 2008;35:45-66. |
|
|
|
7. Muller HP, Holderrieth S, Burkhardt U, Hoffler U. In
vitro antimicrobial susceptibility
of oral strains of Actinobacillus
actinomycetemcomitans to seven antibiotics. J Clin Periodontol.
2002;29:736-42. |
|
|
|
8.
Varela VM, Heller D, Silva-Senem
MX, Torres MC, Colombo AP, Feres-Filho EJ. Systemic antimicrobials adjunctive to a repeated mechanical and antiseptic therapy for aggressive periodontitis: a
6-month randomized controlled
trial. J Periodontol. 2011;82:1121-30. |
|
|
|
9. Mombelli A, Cionca N, Almaghlouth A. Does adjunctive antimicrobial therapy reduce the perceived need for periodontal surgery?. Periodontol 2000. 2011;55:205-16. |
|
|
|
10.
Guerrero A, Griffiths GS, Nibali
L, Suvan J, Moles DR, Laurell
L, et al. Adjunctive benefits
of systemic amoxicillin
and metronidazole in non-surgical
treatment of generalized aggressive periodontitis: a randomized
placebo-controlled clinical
trial. J Clin Periodontol.
2005;32:1096-107. |
|
|
|
11. Griffiths GS, Ayob R, Guerrero
A, Nibali L, Suvan J,
Moles DR, et al. Amoxicillin and metronidazole as an adjunctive treatment in generalized aggressive
periodontitis at initial therapy
or re-treatment: a randomized controlled clinical trial. J Clin Periodontol. 2011;38:43-9. |
|
|
|
12. Aimetti M, Romano F, Guzzi N, Carnevale G. Full-mouth disinfection and systemic antimicrobial therapy in generalized aggressive
periodontitis: a randomized, placebo-controlled trial. J Clin Periodontol. 2012;39:284-94. |
|
|
|
13. Xajigeorgiou C, Sakellari D, Slini T, Baka A, Konstantinidis A. Clinical and microbiological effects of different antimicro-bials on generalized aggressive periodontitis. J Clin
Periodontol. 2006;33:254-64. |
|
|
|
14. Haffajee AD. Systemic antibiotics: to use or not to
use in the treatment of
periodontal infections. That
is the question. J Clin Pe-riodontal. 2006;33:359-61. |
|
|
|
15.
Sanz M, Teughels W, Group
AoEWoP. Innovations in
non-surgical periodontal therapy:
Consensus Report of the Sixth European
Workshop on Periodontology. J Clin Periodontol. 2008;35:3-7. |
|
|
|
16.
Herrera D, Matesanz P, Bascones-Martnez
A, Sanz M. Local and systemic antimicrobial
therapy in periodontics.
J Evid Based Dent Pract. 2012;12
3Suppl:50-60. |
|
|
|
17. Boswell FJ, Andrews JM, Wise R, Dalhoff A. Bactericidal properties of moxifloxacin and post-antibiotic
effect. J Antimicrob Chemother. 1999;43 Suppl
B:43-9. |
|
|
|
18. Eick S, Schmitt A, Sachse S,
Schmidt KH, Pfister W. In vitro antibacterial
activity of fluoroquinolones
against Porphyromonas gingivalis strains. J Antimicrob Chemother.
2004;54:553-6. |
|
|
|
19. Tsaousoglou P, Nietzsche S, Cachovan
G, Sculean A, Eick S. Antibacterial activity of moxifloxacin on bacteria associated with periodontitis within a biofilm. J Med Microbiol. 2014;63:284-92. |
|
|
|
20. Cachovan G, Nergiz I, Thuss U, Siefert HM, Sobottka I, Oral O, et al. Penetration
of moxifloxacin into rat mandibular bone and soft tissue. Acta Odontol Scand. 2009;67:182-6. |
|
|
|
21. Milazzo I, Blandino G, Musumeci R, Nicoletti G, Lo Bue
AM, Speciale A. Antibacterial
activity of moxifloxacin against periodontal anaerobic pathogens involved in systemic infections. Int J Antimicrob Agents. 2002;20:451-6. |
|
|
|
22. Flemmig TF, Petersilka G, Volp A, Gravemeier M, Zilly M, Mross D, et al. Efficacy and safety of adjunctive
local moxifloxacin delivery
in the treatment of
periodontitis. J Periodontol. 2011;82:96-105. |
|
|
|
23.
Tomas I, Tomas M, Alvarez M, Velasco D, Potel C, Limeres J, et al. Susceptibility of oral obligate
anaerobes to telithromycin, moxifloxacin and
a number of commonly used antibacterials. Oral Microbiol Immunol.
2007;22:298-303. |
|
|
|
24. Mombelli A, Cionca N, Almaghlouth A, Decaillet F, Courvoisier DS, Giannopoulou C.
Are there specific benefits of amoxicillin plus metronidazole in Aggregatibacter
actinomycetemcomitans-associa-ted periodontitis? Double-masked, randomized clinical trial of efficacy and
safety. J Periodontol. 2013;84:715-24. |
|
|
|
25.
van Winkelhoff AJ, Rodenburg
JP, Goen RJ, Abbas F, Winkel
EG, de Graaff J. Metronidazole
plus amoxycillin in the treatment of Actinobacillus actinomycetemcomitans associated
periodontitis. J Clin Periodontol.
1989;16:128-31. |
|
|
|
26. Heller D, Varela VM, Silva-Senem
MX, Torres MC, Feres-Filho EJ, Colombo AP. Impact of systemic antimicrobials combined with anti-infective mechanical debridement on the microbiota
of gene-ralized aggressive
periodontitis: a 6-month RCT. J Clin Periodontol. 2011;38:355-64. |
|
|
|
27.
van Winkelhoff AJ. Antibiotics
in periodontics: are we getting somewhere?. J Clin Periodontol.
2005;32:1094-5. |
|
|
|
28.
Sanz M, van Winkelhoff AJ, Herrera D, Dellemijn-Kippuw N, Simon R, Winkel E. Differences in the composition of the subgingival microbiota of two periodontitis
populations of different geographical origin. A comparison between Spain and The Netherlands. Eur J Oral Sci. 2000;108:383-92. |
|
|
|
29.
van Winkelhoff AJ, Winkel
EG. Microbiological diagnostics
in periodontics: biological
significance and clinical
validity. Periodontol
2000. 2005;39:40-52. |
|
|
|
30.
van Winkelhoff AJ, Herrera D, Oteo A, Sanz M. Antimicrobial profiles of
periodontal pathogens isolated
from periodontitis patients
in The Netherlands and Spain. J Clin Periodontol. 2005;32:893-8. |
|
|