de Andrade RS, de Freitas EM, Rocha BA, Gusmão ES, Filho MRM, Júnior HM. Oral findings in secondary syphilis. Med Oral Patol Oral Cir Bucal. 2018 Mar 1;23 (2):e138-43. 

 

 

doi:10.4317/medoral.22196

http://dx.doi.org/doi:10.4317/medoral.22196

 

 

1. WHO Guidelines Approved by the Guidelines Review Committee. WHO Guidelines for the Treatment of Treponema pallidum (syphilis) Geneva: World Health Organization; 2016.

 

2. Akgoz A, Mukundan S, Lee TC. Imaging of rickettsial, spirochetal, and parasitic infections. Neuroimaging Clin N Am. 2012;22:633–57.
https://doi.org/10.1016/j.nic.2012.05.015
PMid:23122260

 

3. Scheurkogel MM, Tim J, Jeurissen FJ, Quarles van Ufford HM. Gummatous syphilis of the adrenal gland. Clin Nucl Med. 2012;37:e231-3.
https://doi.org/10.1097/RLU.0b013e318262adf1
PMid:22889800

 

4. Shim HJ. Tertiary syphilis mimicking hepatic metastases of underlying primary peritoneal serous carcinoma. World J Hepatol. 2010;2:362–6.
https://doi.org/10.4254/wjh.v2.i9.362
PMid:21161022 PMCid:PMC2999301

 

5. Pires FR, da Silva PJ, Natal RF, Alves FA, Pinto CA, Rumayor A, et al. Clinicopathologic features, microvessel density, and immunohistochemical expression of ICAM-1 and VEGF in 15 cases of secondary syphilis with oral manifestations. Oral Surg Oral Med Oral Pathol Oral Radiol. 2016;121:274-81.
https://doi.org/10.1016/j.oooo.2015.09.022
PMid:26682516

 

6. Tamura S, Takimoto Y, Hoshida Y, Okada K, Yoshimura M, Uji K, et al. A case of primary oropharyngeal and gastric syphilis mimicking oropharyngeal cancer. Endoscopy. 2008;40:235–6.
https://doi.org/10.1055/s-2008-1077679
PMid:18991216

 

7. Boellaard R, O'Doherty MJ, Weber WA, Mottaghy FM, Lonsdale MN, Stroobants SG, et al. FDG PET and PET/CT: EANM procedure guidelines for tumour PET imaging: Version 1.0. Eur J Nucl Med Mol Imaging. 2010;37:181-200.
https://doi.org/10.1007/s00259-009-1297-4
PMid:19915839 PMCid:PMC2791475

 

8. Seibt CE, Munerato MC. Secondary syphilis in the oral cavity and the role of the dental surgeon in STD prevention, diagnosis and treatment: a case series study. Braz J Infect Dis. 2016;24:393-399.
https://doi.org/10.1016/j.bjid.2016.03.008
PMid:27208390

 

9. France CM, Mugayar LR. Intrauterine Infections: A literature review. Spec Care Dentist. 2004;24:250-3.
https://doi.org/10.1111/j.1754-4505.2004.tb01701.x

 

10. Walker GJA, Walker DG. Congenital syphilis: A continuing but neglected problem. 2007;12:198-206.

 

11. Epstein, E. Extra genital syphilis in physicians. California medicine. 1952;77:2:149-150.
PMid:12978898 PMCid:PMC1521383

 

12. Ikenberg K, Springer E, Bräuninger W, Kerl K, Mihic D, Schmid S, et al. Oropharyngeal lesions and cervical lymphadenopathy: syphilis is a differential diagnosis that is still relevant. J Clin Pathol. 2010;63:731-6.
https://doi.org/10.1136/jcp.2010.077586
PMid:20702475

 

13. Meyer I, Shklar G. The oral manifestation of acquired syphilis. Oral SurgOral Pathol Oral Med. 1967;23:45-8.
https://doi.org/10.1016/0030-4220(67)90484-7

 

14. Ortega KL, Rezende NP, Magalhães MH. Diagnosing secondary syphilis in a patient with HIV. Br J Oral Maxillofac Surg. 2009;47:169-70.
https://doi.org/10.1016/j.bjoms.2008.08.002
PMid:18801603

 

15. Lee JY, Lin MH, Jung YC. Extragenital syphilitic chancre manifesting as a solitary nodule of the nipple. J Eur Acad Dermatol Venereol. 2006;20:886-887.
https://doi.org/10.1111/j.1468-3083.2006.01560.x

 

16. Lynn WA, Lightman S. Syphilis and HIV: a dangerous combination. Lancet Infect Dis. 2004;4:456-66.
https://doi.org/10.1016/S1473-3099(04)01061-8

 

17. Bruce A, Rogers RS. Oral manifestations of sexually transmitted diseases. Clinics in Dermatology. 2004;22:520-7.
https://doi.org/10.1016/j.clindermatol.2004.07.005
PMid:15596324

 

18. Leão J.C., Gueiros L.A.; Porter S.R. Oral manifestationsofsyphilis. Clinics. 2006;61:2:161-6.
https://doi.org/10.1590/S1807-59322006000200012
PMid:16680334

 

19. Little JW. Syphilis: an update. Oral Surg Oral Med Oral Pathol Oral RadiolEndodontol. 2005;100:3-9.
https://doi.org/10.1016/j.tripleo.2005.03.006
PMid:15953910

 

20. Ficarra G, Carlos R. Syphilis: the renaissance of an old disease with oral implications. Head Neck Pathol. 2009;3:195-206.
https://doi.org/10.1007/s12105-009-0127-0
PMid:20596972 PMCid:PMC2811633

 

21. Poulton M, Dean GL, Williams DI, Carter P, Iversen A, Fisher M. Surfing with spirochaetes: an ongoing syphilis outbreak in Brighton.Sex Trans Inf. 2001;77:619-621.
https://doi.org/10.1136/sti.77.5.319
PMCid:PMC1744365

 

22. Ribeiro CM, de Carli ML, Sperandio FF, Magalhães EMS, Hanemann JAC. Rare isolated oral manifestations of secondary syphilis in an adolescent. Gen Dent. 2017;65:76-8.
PMid:29099372

 

23. Ditzen AK, Braker K, Zoellner KH, Teichman D. The syphilis-HIV interdependency. Int J STD AIDS. 2005;16:642-3.
https://doi.org/10.1258/0956462054944381
PMid:16176637

 

24. Soares AB, Gonzaga HFS, Jorge MA, Barraviera SRCS. Oral manifestations of syphilis: A review. J Venom Anim Toxins incl Trop Dis. 2004;10:2-9.
https://doi.org/10.1590/S1678-91992004000100002

 

25. Eyer-Silva WA, Freire MAL, Horta-Araujo CA, Almeida Rosa da Silva G, Francisco da Cunha Pinto J, Raphael de Almeida Ferry F. Secondary Syphilis Presenting as Glossodynia, Plaques en Prairie Fauchée, and a Split Papule at the Oral Commissure: Case Report and Review. Case Rep Med. 2017;19:897-8.
https://doi.org/10.1155/2017/1980798

 

26. Lautenschlager S. Diagnosis of syphilis: clinical and laboratory problems. JDDG. 2006;4:1058-74.
https://doi.org/10.1111/j.1610-0387.2006.06072.x
https://doi.org/10.1111/j.1610-0387.2006.06072_supp.x
PMid:17176415

 

27. Ramírez-Amador V, Anaya-Saavedra G, Crabtree-Ramírez B, Esquivel-Pedraza L, Saeb-Lima M, Sierra-Madero J. Clinical Spectrum of Oral Secondary Syphilis in HIV-Infected Patients. J Sex Transm Dis. 2013;2013:892427.
https://doi.org/10.1155/2013/892427

 

28. Willeford WG, Bachmann LH. Syphilis ascendant: a brief history and modern trends. Trop Dis Travel Med Vaccines. 2016;26:20.
https://doi.org/10.1186/s40794-016-0039-4
PMid:28883964 PMCid:PMC5530970

 

29. Kelner N, Rabelo GD, da Cruz Perez DE, Assunção JN Jr, Witzel AL, Migliari DA, et al. Analysis of nonspecifc oral mucosal and dermal lesions sugestive of syphilis: a report of 6 cases. Oral Surg oral Med Oral Med Oral Pathol Oral Radiol. 2014;117:1-7.
https://doi.org/10.1016/j.oooo.2012.04.028
PMid:22959147

 

30. Azulay RD. Dermatologia, 2a Ed. Rio de Janeiro: Guanabara Koogan. 1997;10:190-202.