1. Petti S.Pooled estimate of world leukoplakia prevalence: a systematic review. Oral Oncol. 2003;39:770-80.
https://doi.org/10.1016/S1368-8375(03)00102-7

2. Warnakulasuriya KA, Ralhan R. Clinical, pathological, cellular and molecular lesions caused by oral smokeless tobacco--a review. J Oral Pathol Med. 2007;36:63-77.
https://doi.org/10.1111/j.1600-0714.2007.00496.x
PMid:17238967

3. Lee JJ, Hong WK, Hittelman WN, Mao L, Lotan R, Shin DM, et al. Predicting cancer development in oral leukoplakia: ten years of translational research. Clin Cancer Res. 2000;6:1702-10.
PMid:10815888

4. Warnakulasuriya S, Ariyawardana A. Malignant transformation of oral leukoplakia: a systematic review of observational studies. J Oral Pathol Med. 2015;45:155-66
https://doi.org/10.1111/jop.12339
PMid:26189354

5. Silverman S, Bhargava K, Smith LW, Malaowalla AM. Malignant transformation and natural history of oral leukoplakia in 57,518 industrial workers of Gujarat, India. Cancer. 1976;38:1790-5.
https://doi.org/10.1002/1097-0142(197610)38:4<1790::AID-CNCR2820380456>3.0.CO;2-I

6. Napier SS, Cowan CG, Gregg TA, Stevenson M, Lamey PJ, Toner PG. Potentially malignant oral lesions in Northern Ireland: size (extent) matters. Oral Dis. 2003;9:129-37.
https://doi.org/10.1034/j.1601-0825.2003.02888.x
PMid:12945594

7. Silverman S Jr, Gorsky M. Proliferative verrucous leukoplakia: a follow-up study of 54 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1997;84:154-7.
https://doi.org/10.1016/S1079-2104(97)90062-7

8. Scully C. Challenges in predicting which oral mucosal potentially malignant disease will progress to neoplasia. Oral Dis. 2014;20:1-5.
https://doi.org/10.1111/odi.12208
PMid:24320967

9. Bouquot JE, Speight PM, Farthing PM. Epithelial dysplasia of the oral mucosa—Diagnostic problems and prognostic features. Current Diagnostic Pathology. 2006;12:11-21.
https://doi.org/10.1016/j.cdip.2005.10.008

10. Amagasa T, Yamashiro M, Ishikawa H. Oral Leukoplakia Related to Malignant Transformation. Oral Science International. 2006;3:45-55.
https://doi.org/10.1016/S1348-8643(06)80001-7

11. Schepman KP, van der Meij EH, Smeele LE, van der Waal I. Malignant transformation of oral leukoplakia: a follow-up study of a hospital-based population of 166 patients with oral leukoplakia from The Netherlands. Oral Oncol. 1998;34:270-5.
https://doi.org/10.1016/S1368-8375(98)80007-9

12. Lind PO. Malignant transformation in oral leukoplakia. Scand J Dent Res. 1987;95:449-55.
https://doi.org/10.1111/j.1600-0722.1987.tb01959.x

13. Silverman S Jr, Gorsky M, Lozada F. Oral leukoplakia and malignant transformation. A follow-up study of 257 patients. Cancer. 1984;53:563-8.
https://doi.org/10.1002/1097-0142(19840201)53:3<563::AID-CNCR2820530332>3.0.CO;2-F

14. van der Waal I, Schepman KP, van der Meij EH, Smeele LE. Oral leukoplakia: a clinicopathological review. Oral Oncol. 1997;33:291-301.
https://doi.org/10.1016/S1368-8375(97)00002-X

15. Holmstrup P, Vedtofte P, Reibel J, Stoltze K. Long-term treatment outcome of oral premalignant lesions. Oral Oncol. 2006;42:461-474.
https://doi.org/10.1016/j.oraloncology.2005.08.011
PMid:16316774

16. Ho MW, Risk JM, Woolgar JA, Field EA, Field JK, Steele JC, et al. The clinical determinants of malignant transformation in oral epithelial dysplasia. Oral Oncol. 2012;48:969-76.
https://doi.org/10.1016/j.oraloncology.2012.04.002
PMid:22579265

17. Brouns E, Baart J, Karagozoglu K, Aartman I, Bloemena E, van der Waal I. Malignant transformation of oral leukoplakia in a well-defined cohort of 144 patients. Oral Dis. 2014;20:e19-24 .
https://doi.org/10.1111/odi.12095
PMid:23521625

18. Liu W, Shi LJ, Wu L, Feng JQ, Yang X, Li J, et al. Oral cancer development in patients with leukoplakia--clinicopathological factors affecting outcome. PLoS One. 2012;7:e34773.
https://doi.org/10.1371/journal.pone.0034773
PMid:22514665 PMCid:PMC3326047

19. Lee JJ, Hung HC, Cheng SJ, Chen YJ, Chiang CP, Liu BY, et al. Carcinoma and dysplasia in oral leukoplakias in Taiwan: prevalence and risk factors. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006;101:472-80.
https://doi.org/10.1016/j.tripleo.2005.07.024
PMid:16545712

20. Liu W, Bao ZX, Shi LJ, Tang GY, Zhou ZT. Malignant transformation of oral epithelial dysplasia: clinicopathological risk factors and outcome analysis in a retrospective cohort of 138 cases. Histopathology. 2011;59:733-40.
https://doi.org/10.1111/j.1365-2559.2011.03938.x
PMid:21916948

21. Xia RH, Song XM, Wang XJ, Li J, Mao L. The combination of SMAD4 expression and histological grade of dysplasia is a better predictor for the malignant transformation of oral leukoplakia. PLoS One. 2013;8:e66794.
https://doi.org/10.1371/journal.pone.0066794
PMid:23826135 PMCid:PMC3691281

22. Schaaij-Visser TB, Bremmer JF, Braakhuis BJ, Heck AJ, Slijper M, van der Waal I, et al. Evaluation of cornulin, keratin 4, keratin 13 expression and grade of dysplasia for predicting malignant progression of oral leukoplakia. Oral Oncol. 2010;46:123-7.
https://doi.org/10.1016/j.oraloncology.2009.11.012
PMid:20036603

23. Liu W, Wang YF, Zhou HW, Shi P, Zhou ZT, Tang GY. Malignant transformation of oral leukoplakia: a retrospective cohort study of 218 Chinese patients. BMC Cancer. 2010;10:685.
https://doi.org/10.1186/1471-2407-10-685
PMid:21159209 PMCid:PMC3009685

24. Warnakulasuriya S, Johnson NW, van der Waal I. Nomenclature and classification of potentially malignant disorders of the oral mucosa. J Oral Pathol Med. 2007;36:575-80.
https://doi.org/10.1111/j.1600-0714.2007.00582.x
PMid:17944749

25. OMS. International Statistical Classification of Diseases and Related Health Problems 10th Revision (ICD-10) http://apps.who.int/classifications/icd10/browse/2010/en#/C00-C14. Accessed 12 March 2017.

26. van der Waal I, Axell T. Oral leukoplakia: a proposal for uniform reporting. Oral Oncol. 2002;38:521-6.
https://doi.org/10.1016/S1368-8375(01)00125-7

27. Jaber MA. Oral epithelial dysplasia in non-users of tobacco and alcohol: an analysis of clinicopathologic characteristics and treatment outcome. J Oral Sci. 2010;52:13-21.
https://doi.org/10.2334/josnusd.52.13
PMid:20339228

28. Gale N, Pilch BZ, Sidransky D, El Naggar A, Westra W, Califano J, et al. Epithelial precursor lesions. In: Barnes L, Eveson JW, Reichart P, Sidransky D (ed). World health organization classification of tumours. Pathology and genetics. Head and neck tumours. 1st edn. IARC Press, Lyon, 2005, pp 177-9.

29. Brouns ER, Baart JA, Bloemena E, Karagozoglu H, van der Waal I. The relevance of uniform reporting in oral leukoplakia: definition, certainty factor and staging based on experience with 275 patients. Med Oral Patol Oral Cir Bucal 2013;18:19-26.
https://doi.org/10.4317/medoral.18756
PMCid:PMC3548640

30. van der Waal I, Schepman KP, van der Meij EH. A modified classification and staging system for oral leukoplakia. Oral Oncol. 2000;36:264-6.
https://doi.org/10.1016/S1368-8375(99)00092-5

31. Schepman KP, van der Waal I. A proposal for a classification and staging system for oral leukoplakia: a preliminary study. Eur J Cancer B Oral Oncol. 1995;31B:396-8.
https://doi.org/10.1016/0964-1955(95)00032-1

32. Chandu A, Smith AC. The use of CO2 laser in the treatment of oral white patches: outcomes and factors affecting recurrence. Int J Oral Maxillofac Surg. 2005;34:396-400.
https://doi.org/10.1016/j.ijom.2004.10.003
PMid:16053849

33. Banoczy J. Follow-up studies in oral leukoplakia. J Maxillofac Surg. 1997;5:69-75.
https://doi.org/10.1016/S0301-0503(77)80079-9

34. Lumerman H, Freedman P, Kerpel S. Oral epithelial dysplasia and the development of invasive squamous cell carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1995;79:321-9.
https://doi.org/10.1016/S1079-2104(05)80226-4

35. Slaughter DP, Southwick HW, Smejkal W. Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric origin. Cancer. 1953;6:963-8.
https://doi.org/10.1002/1097-0142(195309)6:5<963::AID-CNCR2820060515>3.0.CO;2-Q

36. Thomson PJ. Field change and oral cancer: new evidence for widespread carcinogenesis? Int J Oral Maxillofac Surg. 2002;31:262-6.
https://doi.org/10.1054/ijom.2002.0220
PMid:12190131

37. Chandran R, Meer S, Feller L. Oral leukoplakia in a South African sample: a clinicopathological study. Oral Dis. 2013;19:592-7.
https://doi.org/10.1111/odi.12040
PMid:23210506

38. Saito T, Sugiura C, Hirai A, Notani K, Totsuka Y, Shindoh M, et al. Development of squamous cell carcinoma from pre-existent oral leukoplakia: with respect to treatment modality. Int J Oral Maxillofac Surg. 2001;30:49-53.
https://doi.org/10.1054/ijom.2000.0012
PMid:11289621

39. Mashberg A, Meyers H. Anatomical site and size of 222 early asymptomatic oral squamous cell carcinomas: a continuing prospective study of oral cancer. II. Cancer. 1076;37:2149-57.
https://doi.org/10.1002/1097-0142(197605)37:5<2149::AID-CNCR2820370502>3.0.CO;2-G

40. Castagnola P, Malacarne D, Scaruffi P, Maffei M, Donadini A, Di Nallo E, et al. Chromosomal aberrations and aneuploidy in oral potentially malignant lesions: distinctive features for tongue. BMC Cancer. 2011;11:445.
https://doi.org/10.1186/1471-2407-11-445
PMid:21995418 PMCid:PMC3229618

41. Zhang L, Cheung KJ,Jr, Lam WL, Cheng X, Poh C, Priddy R, et al. Increased genetic damage in oral leukoplakia from high risk sites: potential impact on staging and clinical management. Cancer. 2001;91:2148-55.
https://doi.org/10.1002/1097-0142(20010601)91:11<2148::AID-CNCR1243>3.0.CO;2-G