Corrêa LBC, Basso MB, Sousa-Pinto B, Coelho Leal S. Oral health effects of botulinum toxin treatment for drooling: a systematic review. Med Oral Patol Oral Cir Bucal. 2021 Mar 1;26 (2):e172-80.
doi:10.4317/medoral.24101
https://dx.doi.org/doi:10.4317/medoral.24101
1. Morgante F, Bavikatte G, Anwar F, Mohamed B. The burden of sialorrhoea in chronic neurological conditions: current treatment options and the role of incobotulinumtoxinA (Xeomin®). Ther Adv Neurol Disord. 2019;12:1-21. |
PMid:31819763 PMCid:PMC6883364 |
2. Isaacson SH, Ondo W, Jackson CE, Trosch RM, Molho E, Pagan F, et al. Safety and Efficacy of RimabotulinumtoxinB for Treatment of Sialorrhea in Adults. JAMA Neurol. 2020;77:E1-9. |
PMid:31930364 PMCid:PMC6990829 |
3. Varley LP, Denieffe S, O'Gorman C, Murphy A, Gooney M. A systematic review of noninvasive and invasive sialorrhoea management. J Clin Nurs. 2019;28:4190-206. |
PMid:31318993 |
4. Abboud WA, Nadel S, Hassin-Baer S, Arad A, Dobriyan A, Yahalom R. Ultrasound-Guided Botulinum Toxin Injections into the Salivary Glands for the Treatment of Drooling. Isr Med Assoc J. 2019;2:116-9. |
PMid:30772963 |
5. Taib BG, Williams SP, Sood S, Ung K, Nixon PP, Sharma R. Treatment of sialorrhoea with repeated ultrasound-guided injections of botulinum toxin A into the parotid and submandibular glands. Br J Oral Maxillofac Surg. 2019;57:442-8. |
PMid:31010597 |
6. Jost WH, Friedman A, Michel O, Oehlwein C, Slawek J, Bogucki A, et al. Long-term incobotulinumtoxinA treatment for chronic sialorrhea: Efficacy and safety over 64 weeks. Parkinsonism Relat Disord. 2020;70:23-30. |
PMid:31794936 |
7. Jost WH, Friedman A, Michel O, Oehlwein C, Slawek J, Bogucki A, et al. SIAXI. Neurology. 2019;92:e1982-91. |
PMid:30918101 PMCid:PMC6511076 |
8. Paracka L, Kollewe K, Klietz M, Petri S, Dressler D. IncobotulinumtoxinA for hypersalivation in patients with amyotrophic lateral sclerosis: an open-label single-centre study. J Neural Transm. 2019;126:1341-5. |
PMid:31317261 |
9. Lamb R, Rohrer JD, Lees AJ, Morris HR. Progressive Supranuclear Palsy and Corticobasal Degeneration: Pathophysiology and Treatment Options. Curr Treat Options Neurol. 2016;18:42-59. |
PMid:27526039 PMCid:PMC4985534 |
10. Jackson CE, Gronseth G, Rosenfeld J, Barohn RJ, Dubinsky R, Simpson CB, et al. Randomized double-blind study of botulinum toxin type B for sialorrhea in als patients. Muscle Nerve. 2009;39:137-43. |
PMid:19145653 |
11. Ondo WG, Hunter C, Moore W. A double-blind placebo-controlled trial of botulinum toxin B for sialorrhea in Parkinson's disease. Neurology. 2004;62:37-40. |
PMid:14718694 |
12. Porte M, Chaléat-Valayer E, Patte K, D'Anjou M-C, Boulay C, Laffont I. Relevance of intraglandular injections of Botulinum toxin for the treatment of sialorrhea in children with cerebral palsy: A review. Eur J Paediatr Neurol. 2014;18:649-57. |
PMid:24931915 |
13. Gutierrez G, Siqueira V, Loyola-Rodriguez J, Diniz M, Guare R, Ferreira A, et al. Effects of treatments for drooling on caries risk in children and adolescents with cerebral palsy. Med Oral Patol Oral y Cir Bucal. 2019;24:e204-10. |
PMid:30818313 PMCid:PMC6441593 |
14. Pedersen AML, Sørensen CE, Proctor GB, Carpenter GH, Ekström J. Salivary secretion in health and disease. J Oral Rehabil. 2018;45:730-46. |
PMid:29878444 |
15. Mese H, Matsuo R. Salivary secretion, taste and hyposalivation. J Oral Rehabil. 2007;34:711-23. |
PMid:17824883 |
16. Møller E, Pedersen S, Vinicoff P, Bardow A, Lykkeaa J, Svendsen P, et al. Onabotulinumtoxin A Treatment of Drooling in Children with Cerebral Palsy: A Prospective, Longitudinal Open-Label Study. Toxins (Basel). 2015;7:2481-93. |
PMid:26134257 PMCid:PMC4516924 |
17. Møller E, Daugaard D, Holm O, Winge K, Bardow A, Lykkeaa J, et al. Repeated treatments of drooling with botulinum toxin B in neurology. Acta Neurol Scand. 2015;131:51-7. |
PMid:25270197 |
18. Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement. Int J Surg. 2010;8:336-41. |
PMid:20171303 |
19. Sterne JAC, Savović J, Page MJ, Elbers RG, Blencowe NS, Boutron I, et al. RoB 2: a revised tool for assessing risk of bias in randomised trials. BMJ. 2019;366:l4898. |
PMid:31462531 |
20. Sterne JA, Hernán MA, Reeves BC, Savović J, Berkman ND, Viswanathan M, et al. ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions. BMJ. 2016;355:i4919-26. |
PMid:27733354 PMCid:PMC5062054 |
21. Wu KPH, Ke JY, Chen CY, Chen CL, Chou MY, Pei YC. Botulinum Toxin Type A on Oral Health in Treating Sialorrhea in Children With Cerebral Palsy: A Randomized, Double-Blind, Placebo-Controlled Study. J Child Neurol. 2011;26:838-43. |
PMid:21551374 |
22. Tiigimäe-Saar J, Tamme T, Rosenthal M, Kadastik-Eerme L, Taba P. Saliva changes in Parkinson's disease patients after injection of Botulinum neurotoxin type A. Neurol Sci. 2018;39:871-7. |
PMid:29460161 |
23. Tiigimäe-Saar J, Taba P, Tamme T. Does Botulinum neurotoxin type A treatment for sialorrhea change oral health? Clin Oral Investig. 2017;21:795-800. |
PMid:27114092 |
24. Müller VJ, Belibasakis GN, Bosshard PP, Wiedemeier DB, Bichsel D, Rücker M, et al. Change of saliva composition with radiotherapy. Arch Oral Biol. 2019;106:104480-8. |
PMid:31325717 |
25. Mummolo S, Marchetti E, Giuca MR, Gallusi G, Tecco S, Gatto R, et al. In-office bacteria test for a microbial monitoring during the conventional and self-ligating orthodontic treatment. Head Face Med. 2013;9:1-8. |
PMid:23375053 PMCid:PMC3563582 |
26. Zhang L, Sun T, Zhu P, Sun Z, Li S, Li F, et al. Quantitative Analysis of Salivary Oral Bacteria Associated with Severe Early Childhood Caries and Construction of Caries Assessment Model. Sci Rep. 2020;10:6365-73. |
PMid:32286402 PMCid:PMC7156402 |
27. Jiang S, Gao X, Jin L, Lo E. Salivary Microbiome Diversity in Caries-Free and Caries-Affected Children. Int J Mol Sci. 2016;17:1978-91. |
PMid:27898021 PMCid:PMC5187778 |
28. Simón-Soro A, Mira A. Solving the etiology of dental caries. Trends Microbiol. 2015;23:76-82. |
PMid:25435135 |
29. Simón-Soro Á, Tomás I, Cabrera-Rubio R, Catalan MD, Nyvad B, Mira A. Microbial Geography of the Oral Cavity. J Dent Res. 2013;92:616-21. |
PMid:23674263 |
30. Goetz CG, Tilley BC, Shaftman SR, Stebbins GT, Fahn S, Martinez-Martin P, et al. Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS): Scale presentation and clinimetric testing results. Mov Disord. 2008;23:2129-70. |
PMid:19025984 |
31. Santos MT, Guaré R, Leite M, Ferreira MC, Nicolau J. Does the neuromotor abnormality type affect the salivary parameters in individuals with cerebral palsy? J Oral Pathol Med. 2010;39:770-4. |
PMid:20738750 |
32. Humphrey SP, Williamson RT. A review of saliva: Normal composition, flow, and function. J Prosthet Dent. 2001;85:162-9. |
PMid:11208206 |
33. Holmberg KV, Hoffman MP. Anatomy, Biogenesis and Regeneration of Salivary Glands. In: Monographs in Oral Science. 2014;24:1-13. |
PMid:24862590 PMCid:PMC4048853 |
34. Jost WH, Bäumer T, Laskawi R, Slawek J, Spittau B, Steffen A, et al. Therapy of Sialorrhea with Botulinum Neurotoxin. Neurol Ther. 2019;8:273-88. |
PMid:31542879 PMCid:PMC6858891 |
35. Ferraz dos Santos B, Dabbagh B, Daniel SJ, Schwartz S. Association of onabotulinum toxin A treatment with salivary pH and dental caries of neurologically impaired children with sialorrhea. Int J Paediatr Dent. 2016;26:45-51. |
PMid:25726732 |