Shi Y, Li M, Yu Y, Zhou Y, Wang S. Whole exome sequencing and system biology analysis support the "two-hit" mechanism in the onset of Ameloblastoma. Med Oral Patol Oral Cir Bucal. 2021 Jul 1;26 (4):e510-7.
doi:10.4317/medoral.24385
https://dx.doi.org/doi:10.4317/medoral.24385
1. Hendra FN, Van Cann EM, Helder MN, Ruslin M, de Visscher JG, Forouzanfar T, et al. Global incidence and profile of ameloblastoma: A systematic review and meta-analysis. Oral Dis. 2020;26:12-21. |
PMid:30614154 |
2. Effiom OA, Ogundana OM, Akinshipo AO, Akintoye SO. Ameloblastoma: current etiopathological concepts and management. Oral Dis. 2018;24:307-16. |
PMid:28142213 |
3. Sweeney RT, McClary AC, Myers BR, Biscocho J, Neahring L, Kwei KA, et al. Identification of recurrent SMO and BRAF mutations in ameloblastomas. Nat Genet. 2014;46:722-5. |
PMid:24859340 PMCid:PMC4418232 |
4. Rizzitelli A, Smoll NR, Chae MP, Rozen WM, Hunter-Smith DJ. Incidence and overall survival of malignant ameloblastoma. PLoS One. 2015;10:e0117789. |
PMid:25692490 PMCid:PMC4333213 |
5. Almeida RDAC, Andrade ESDS, Barbalho JC, Vajgel A, Vasconcelos BCDE. Recurrence rate following treatment for primary multicystic ameloblastoma: Systematic review and meta-analysis. Int J Oral Maxillofac Surg. 2016;45:359-67. |
PMid:26792147 |
6. Guan P, Wong SF, Lim JQ, Ng CCY, Soong PL, Sim CQX, et al. Mutational Signatures in Mandibular Ameloblastoma Correlate with Smoking. J Dent Res. 2019;98:652-8. |
PMid:30917298 |
7. Brown NA, Rolland D, McHugh JB, Weigelin HC, Zhao L, Lim MS, et al. Activating FGFR2-RAS-BRAF mutations in ameloblastoma. Clin Cancer Res. 2014;20:5517-26. |
PMid:24993163 |
8. Kurppa KJ, Catón J, Morgan PR, Ristimäki A, Ruhin B, Kellokoski J, et al. High frequency of BRAF V600E mutations in ameloblastoma. J Pathol. 2014;232:492-8. |
PMid:24374844 PMCid:PMC4255689 |
9. Niault TS, Baccarini M. Targets of Raf in tumorigenesis. Carcinogenesis. 2010;31:1165-74. |
PMid:20047953 |
10. Hu S, Parker J, Wright JT. Towards unraveling the human tooth transcriptome: The dentome. PLoS One. 2015;10:e0124801. |
PMid:25849153 PMCid:PMC4388651 |
11. Hu S, Parker J, Divaris K, Padilla R, Murrah V, Wright JT. Ameloblastoma Phenotypes Reflected in Distinct Transcriptome Profiles. Sci Rep. 2016;6:30867. |
PMid:27491308 PMCid:PMC4974613 |
12. Li H, Durbin R. Fast and accurate long-read alignment with Burrows-Wheeler transform. Bioinformatics. 2010;26:589-95. |
PMid:20080505 PMCid:PMC2828108 |
13. Koboldt DC, Zhang Q, Larson DE, Shen D, McLellan MD, Lin L, et al. VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing. Genome Res. 2012;22:568-76. |
PMid:22300766 PMCid:PMC3290792 |
14. Yang H, Wang K. Genomic variant annotation and prioritization with ANNOVAR and wANNOVAR. Nat Protoc. 2015;10:1556-66. |
PMid:26379229 PMCid:PMC4718734 |
15. 1000 Genomes Project Consortium. A global reference for human genetic variation. Nature. 2015;526:68-74. |
PMid:26432245 PMCid:PMC4750478 |
16. Lek M, Karczewski KJ, Minikel EV, Samocha KE, Banks E, Fennell T, et al. Analysis of protein-coding genetic variation in 60,706 humans. Nature. 2016;536:285-91. |
PMid:27535533 PMCid:PMC5018207 |
17. Karczewski KJ, Francioli LC, Tiao G, Cummings BB, Alföldi J, Wang Q, et al. Variation across 141,456 human exomes and genomes reveals the spectrum of loss-of-function intolerance across human protein-coding genes. bioRxiv. 2019;531:210. |
PMid: |
18. Kircher M, Witten DM, Jain P, O'Roak BJ, Cooper GM, Shendure J. A general framework for estimating the relative pathogenicity of human genetic variants. Nat Genet. 2014;46:310-5. |
PMid:24487276 PMCid:PMC3992975 |
19. Sim NL, Kumar P, Hu J, Henikoff S, Schneider G, Ng PC. SIFT web server: predicting effects of amino acid substitutions on proteins. Nucleic Acids Res. 2012;40:W452-7. |
PMid:22689647 PMCid:PMC3394338 |
20. Adzhubei IA, Schmidt S, Peshkin L, Ramensky VE, Gerasimova A, Bork P, et al. A method and server for predicting damaging missense mutations. Nat Methods. 2010;7:248-9. |
PMid:20354512 PMCid:PMC2855889 |
21. Langfelder P, Horvath S. WGCNA: an R package for weighted correlation network analysis. BMC Bioinformatics. 2008;9:559. |
PMid:19114008 PMCid:PMC2631488 |
22. Shannon P, Markiel A, Ozier O, Baliga NS, Wang JT, Ramage D, et al. Cytoscape: A Software Environment for Integrated Models of Biomolecular Interaction Networks. Genome Res. 2003;13:2498-504. |
PMid:14597658 PMCid:PMC403769 |
23. Yu G, Wang LG, Han Y, He QY. clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters. Omi A J Integr Biol. 2012;16:284-7. |
PMid:22455463 PMCid:PMC3339379 |
24. Kurppa KJ, Catón J, Morgan PR, Ristimäki A, Ruhin B, Kellokoski J, et al. High frequency of BRAFV600E mutations in ameloblastoma. J Pathol. 2014;232:492-8. |
PMid:24374844 PMCid:PMC4255689 |
25. Yang Z, Zhuang L, Szatmary P, Wen L, Sun H, Lu Y, et al. Upregulation of heat shock proteins (HSPA12A, HSP90B1, HSPA4, HSPA5 and HSPA6) in tumour tissues is associated with poor outcomes from HBV-related early-stage hepatocellular carcinoma. Int J Med Sci. 2015;12:256-63. |
PMid:25798051 PMCid:PMC4366630 |
26. Knudson AG. Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sci U S A. 1971;68:820-3. |
PMid:5279523 PMCid:PMC389051 |