Mattos-Pereira GH, Martins CC, Esteves-Lima RP, Alvarenga-Brant R, Cota LO, Costa FO. Preemptive analgesia in dental implant surgery: A systematic review and meta-analysis of randomized controlled trials. Med Oral Patol Oral Cir Bucal. 2021 Sep 1;26 (5):e632-41.


doi:10.4317/medoral.24639

https://dx.doi.org/doi:10.4317/medoral.24639


1. Lovich-Sapola J, Smith CE, Brandt CP. Postoperative pain control. Surg Clin North Am. 2015;95:301-18.

https://doi.org/10.1016/j.suc.2014.10.002

PMid:25814108 

2. Rosero EB, Joshi GP. Preemptive, preventive, multimodal analgesia: What do they really mean?. Plast Reconstr Surg. 2014;134:85S-93S.

https://doi.org/10.1097/PRS.0000000000000671

PMid:25255012 

3. Cetira Filho EL, Carvalho FSR, de Barros Silva PG, Barbosa DAF, Alves Pereira KM, Ribeiro TR, et al. Preemptive use of oral nonsteroidal anti-inflammatory drugs for the relief of inflammatory events after surgical removal of lower third molars: A systematic review with meta-analysis of placebo-controlled randomized clinical trials. J Craniomaxillofac Surg. 2020;48:293-307.

https://doi.org/10.1016/j.jcms.2020.01.016

PMid:32070661 

4. Bahammam MA, Kayal RA, Alasmari DS, Attia MS, Bahammam LA, Hassan MH, et al. Comparison between dexamethasone and ibuprofen for postoperative pain prevention and control after surgical implant placement: A double-masked, parallel-group, placebo-controlled randomized clinical trial. J Periodontol. 2017;88:69-77.

https://doi.org/10.1902/jop.2016.160353

PMid:27562219 

5. Kelly DJ, Ahmad M, Brull SJ. Preemptive analgesia I: Physiological pathways and pharmacological modalities. Can J Anaesth. 2001;48:1000-10.

https://doi.org/10.1007/BF03016591

PMid:11698320 

6. Campbell WI, Kendrick RW, Fee JP. Balanced pre-emptive analgesia: does it work? A double-blind, controlled study in bilaterally symmetrical oral surgery. Br J Anaesth.1998;81:727-30.

https://doi.org/10.1093/bja/81.5.727

PMid:10193284 

7. Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. BMJ. 2021;372:71.

https://doi.org/10.1136/bmj.n71

PMid:33782057 PMCid:PMC8005924

8. Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ. 2003;327:557-60.

https://doi.org/10.1136/bmj.327.7414.557

PMid:12958120 PMCid:PMC192859

9. Zhang Y, Akl EA, Schünemann HJ. Using systematic reviews in guideline development: The GRADE approach [published online ahead of print, 2018 Jul 14]. Res Synth Methods. 2018.

https://doi.org/10.1002/jrsm.1313

PMid:30006970 

10. Martins CC, Firmino RT, Riva JJ, Ge L, Carrasco-Labra A, Brignardello-Petersen R, et al. Desensitizing toothpastes for dentin hypersensitivity: A network meta-analysis. J Dent Res. 2020;99:514-22.

https://doi.org/10.1177/0022034520903036

PMid:32037944 

11. Santesso N, Glenton C, Dahm P, Garner P, Akl EA, Alper B, et al. GRADE Working Group. GRADE guidelines 26: Informative statements to communicate the findings of systematic reviews of interventions. J Clin Epidemiol. 2020;119:126-35.

https://doi.org/10.1016/j.jclinepi.2019.10.014

PMid:31711912 

12. Bhutani N, Sangolikar D, Bhutani S, Tapashetti R, Pushpalatha H. Sublingual piroxicam as preemptive analgesia in single implant surgery. J Contemp Dent Pract. 2019;20:750-53.

https://doi.org/10.5005/jp-journals-10024-2591

PMid:31358721 

13. Sánchez-Pérez A, Muñoz-Peñalver J, Moya-Villaescusa MJ, Sánchez-Matás C. Effects of the preoperative administration of dexketoprofen trometamol on pain and swelling after implant surgery: A randomized, double-blind controlled trial. J Oral Implantol. 2018;44:122-29.

https://doi.org/10.1563/aaid-joi-D-17-00185

PMid:29356603 

14. Mattos Pereira G, Cota LO, Lima RP, Costa FO. Effect of preemptive analgesia with ibuprofen in the control of postoperative pain in dental implant surgeries: A randomized, triple-blind controlled clinical trial. J Clin Exp Dent. 2020;12:e71-8.

https://doi.org/10.4317/jced.56171

PMid:31976047

15. Bailey E. Prevention and management of post-operative pain in oral surgery. Prim Dent J. 2018;7:57-63.

https://doi.org/10.1177/205016841800700309

PMid:30428969 

16. Ong CK, Seymour RA. An evidence-based update of the use of analgesics in dentistry. Periodontol 2000. 2008;46:143-64.

https://doi.org/10.1111/j.1600-0757.2008.00225.x

PMid:18201349 

17. Sisk AL, Grover, BJ. A comparison of preoperative and postoperative naproxen sodium for suppression of postoperative pain. J Oral Maxillofac Surg. 1990;48:674-78.

https://doi.org/10.1016/0278-2391(90)90048-7

PMid:2358942

18. Scott RE, Ellis E 3rd, Upton LG. Double-blind evaluation of etodolac (200 mg, 400 mg) compared with zomepirac (100 mg) and placebo on third molar extraction pain. Oral Surg Oral Med Oral Pathol. 1986;62:638-42.

https://doi.org/10.1016/0030-4220(86)90255-0

PMid:2948143

19. Kaczmarzyk T, Wichlinski J, Stypulkowska J, Zaleska M, Woron J. Preemptive effect of ketoprofen on postoperative pain following third molar surgery: A prospective, randomized, double-blinded clinical trial. Int J Oral Maxillofac Surg. 2010;39:647-52.

https://doi.org/10.1016/j.ijom.2010.02.019

PMid:20338728 

20. Santos BFE, Costa FO, Vasconcelos AMA, Cyrino RM, Cota LOM. Preemptive effects of ibuprofen and nimesulide on postoperative pain control after open flap periodontal surgeries: a randomized placebo-controlled split-mouth clinical trial. J Periodontol. 2021.

https://doi.org/10.1002/JPER.20-0887

PMid:34031888 

21. Aznar-Arasa L, Harutunian K, Figueiredo R, Valmaseda-Castellón E, Gay-Escoda C. Effect of preoperative ibuprofen on pain and swelling after lower third molar removal: a randomized controlled trial. Int J Oral Maxillofac Surg. 2012;41:1005-9.

https://doi.org/10.1016/j.ijom.2011.12.028

PMid:22521671 

22. Costa FW, Soares EC, Esses DF, Silva PG, Bezerra TP, Scarparo HC, et al. A split-mouth, randomized, triple-blind, placebo-controlled study to analyze the pre-emptive effect of etoricoxib 120 mg on inflammatory events following removal of unerupted mandibular third molars. Int J Oral Maxillofac Surg. 2015;44:1166-74.

https://doi.org/10.1016/j.ijom.2015.06.012

PMid:26144571 

23. O'Brien TP, Roszkowski MT, Wolff LF, Hinrichs JE, Hargreaves KM. Effect of a non-steroidal anti-inflammatory drug on tissue levels of immunoreactive prostaglandin E2, immunoreactive leukotriene, and pain after periodontal surgery. J Periodontol. 1996;67:1307-16.

https://doi.org/10.1902/jop.1996.67.12.1307

PMid:8997678 

24. Roszkowski MT, Swift JQ, Hargreaves KM. Effect of NSAID administration on tissue levels of immunoreactive prostaglandin E2, leukotriene B4, and (S)-flurbiprofen following extraction of impacted third molars. Pain. 1997;73:339-45.

https://doi.org/10.1016/S0304-3959(97)00120-6

PMid:9469523

25. Kantor TG. Ibuprofen. Ann Intern Med. 1979;91:877-82.

https://doi.org/10.7326/0003-4819-91-6-877

PMid:391117 

26. Laska EM, Sunshine A, Marrero I, Olson N, Siegel C, McCormick N. The correlation between blood levels of ibuprofen and clinical analgesic response. Clin Pharmacol Ther. 1986;40:1-7.

https://doi.org/10.1038/clpt.1986.129

PMid:3522030 

27. Moore PA, Ziegler KM, Lipman RD, Aminoshariae A, Carrasco-Labra A, Mariotti A. Benefits and harms associated with analgesic medications used in the management of acute dental pain: An overview of systematic reviews. J Am Dent Assoc. 2018;149:256-65.

https://doi.org/10.1016/j.adaj.2018.02.012

PMid:29599019 

28. Jiménez-Martínez E, Gasco-García C, Arrieta-Blanco JJ, Gomez del Torno J, Bartolome Villar B. Study of the analgesic efficacy of dexketoprofen trometamol 25mg. vs. ibuprofen 600mg after their administration in patients subjected to oral surgery. Med Oral. 2004;9:138-48.

PMid:14990880

29. Guyatt GH, Oxman AD, Kunz R, Woodcock J, Brozek J, Helfand M, et al. GRADE Working Group. GRADE guidelines: 7. Rating the quality of evidence--inconsistency. J Clin Epidemiol. 2011;64:1294-302.

https://doi.org/10.1016/j.jclinepi.2011.03.017

PMid:21803546 

30. Katyal V. The efficacy and safety of articaine versus lignocaine in dental treatments: A meta-analysis. J Dent. 2010;38:307-17.

https://doi.org/10.1016/j.jdent.2009.12.003

PMid:20006669 

31. St George G, Morgan A, Meechan J, Moles DR, Needleman I, Ng YL, et al. Injectable local anaesthetic agents for dental anaesthesia. Cochrane Database Syst Rev. 2018;7:CD006487.

https://doi.org/10.1002/14651858.CD006487.pub2

PMid:29990391 PMCid:PMC6513572

32. Figueiredo R, Sofos S, Soriano-Pons E, Camps-Font O, Sanmarti-García G, Gay-Escoda C, et al. Is it possible to extract lower third molars with infiltration anaesthesia techniques using articaine? A double-blind randomized clinical trial. Acta Odontol Scand. 2021;79:1-8.

https://doi.org/10.1080/00016357.2020.1760348

PMid:32401086