Kaba YN, Demirbas AE, Kütük N, Canpolat DG, Alkan A. Does preventive single dose of intravenous dexketoprofen reduce pain and swelling after orthognathic surgery? A prospective, randomized, double blind clinical trial. Med Oral Patol Oral Cir Bucal. 2023 May 1;28 (3):e199-207.


doi:10.4317/medoral.24852

https://dx.doi.org/doi:10.4317/medoral.24852


1. Phillips C, Blakey G. Short-term Recovery after Orthognathic Surgery: A Medical Daily Diary Approach. Int J Oral Maxillofac Surg. 2008;37:892-6.

https://doi.org/10.1016/j.ijom.2008.07.005

PMid:18768296 PMCid:PMC2590780

2. Gupta A, Chowdhury R, Haring RS, Leinbach LI, Petrone J, Spitzer MJ, et al. Length of stay and cost in patients undergoing orthognathic surgery: Does surgeon volume matter?. J Oral Maxillofac Surg. 2017;75:1948-57.

https://doi.org/10.1016/j.joms.2017.04.041

PMid:28576668 

3. Nagatsuka C, Ichinohe T, Kaneko Y. Preemptive effects of a combination of preoperative diclofenac, butorphanol, and lidocaine on postoperative pain management following orthognathic surgery. Anesth Prog. 2000;47:119-24.

PMid:11432176

4. Kissin I, Weiskopf RB. Preemptive analgesia. J Am Soc Anesthesiol. 2000;93:1138-43.

https://doi.org/10.1097/00000542-200010000-00040

PMid:11020772 

5. Grape S, Tramèr MR. Do we need preemptive analgesia for the treatment of postoperative pain?. Best Practice and Research: Clinical Anaesthesiology. 2007;2:51-63.

https://doi.org/10.1016/j.bpa.2006.11.004

PMid:17489219 

6. Møiniche S, Kehlet H, Dahl JB. A qualitative and quantitative systematic review of preemptive analgesia for postoperative pain relief: The role of timing of analgesia. Anesthesiology. 2002;96:725-41.

https://doi.org/10.1097/00000542-200203000-00032

PMid:11873051 

7. Tuzuner AM, Ucok C, Kucukyavuz Z, Alkis N, Alanoglu Z. Preoperatıve Diclofenac Sodium and Tramadol for Pain Relief After Bimaxillary Osteotomy. J Oral Maxillofac Surg. 2007;65:2453-8.

https://doi.org/10.1016/j.joms.2007.06.622

PMid:18022468 

8. Öncül AMT, Çimen E, Küçükyavuz Z, Cambazoğlu M. Postoperative analgesia in orthognathic surgery patients: diclofenac sodium or paracetamol?. Br J Oral Maxillofac Surg. 2011;49:138-41.

https://doi.org/10.1016/j.bjoms.2010.04.017

PMid:20621401 

9. Ahiskalioglu A, Ince I, Aksoy M, Yalcin E, Ahiskalioglu EO, Kilinc A. Effects of a single-dose of pre-emptive pregabalin on postoperative pain and opioid consumption after double-jaw surgery: A randomized controlled trial. J Oral Maxillofac Surg. 2016;74:53.e1-7

https://doi.org/10.1016/j.joms.2015.09.008

PMid:26433040 

10. Samieirad S, Sharifian-Attar A, Eshghpour M, Mianbandi V, Shadkam E, Hosseini-Abrishami M, et al. Comparison of ondansetron versus Clonidine efficacy for prevention of postoperative pain, nausea and vomiting after Orthognathic surgeries: A triple blind randomized controlled trial. Med Oral Patol Oral y Cir Bucal. 2018;23:e767.

https://doi.org/10.4317/medoral.22493

PMid:30341261 PMCid:PMC6261005

11. Chen YA, Rivera-Serrano CM, Chen C, Chen YR. Pre-surgical regional blocks in orthognathic surgery: Prospective study evaluating their influence on the intraoperative use of anaesthetics and blood pressure control. Int J Oral Maxillofac Surg. 2016;45:783-6.

https://doi.org/10.1016/j.ijom.2015.09.014

PMid:26811189 

12. Rana M, Gellrich NC, Joos U, Piffkó J, Kater W. 3D evaluation of postoperative swelling using two different cooling methods following orthognathic surgery: A randomised observer blind prospective pilot study. Int J Oral Maxillofac Surg. 2011;40:690-6

https://doi.org/10.1016/j.ijom.2011.02.015

PMid:21411291 

13. Fletcher MC, Spera JF. Management of Acute Postoperative Pain after Oral Surgery. Dental Clinics of North America. 2012;56:95-111.

https://doi.org/10.1016/j.cden.2011.09.001

PMid:22117944 

14. Gaskell H, Derry S, Wiffen PJ, Moore RA. Single dose oral ketoprofen or dexketoprofen for acute postoperative pain in adults. Cochrane Database of Systematic Reviews. 2017;25:CD007355

https://doi.org/10.1002/14651858.CD007355.pub3

PMid:28540716 PMCid:PMC6481461

15. Barbanoj MJ, Antonijoan RM, Gich I. Clinical pharmacokinetics of dexketoprofen. Clinical Pharmacokinetics. 2001;40:245-62.

https://doi.org/10.2165/00003088-200140040-00002

PMid:11368291 

16. Neal CE, Kiyak HA. Patient perceptions of pain, paresthesia, and swelling after orthognathic surgery. Int J Adult Orthodon Orthognath Surg. 1991;6:169-81.

PMid:1812182

17. Niederhagen B, Braumann B, Dierke-Dzierzon C, Albrecht S. Postoperative pain after interventions in the area of the mouth-jaw-face. Mund Kiefer Gesichtschir. 1997;1:229-34.

https://doi.org/10.1007/BF03043555

PMid:9410633 

18. Precious DS, Multari J, Finley GA, Mcgrath P. A comparison of patient-controlled and fixed schedule analgesia after orthognathic surgery. J Oral Maxillofac Surg. 1997;55:33-9.

https://doi.org/10.1016/S0278-2391(97)90442-0

PMid:8994466 

19. Laporte J-R, Ibanez L, Vidal X, Vendrell L, Leone R. Upper gastrointestinal bleeding associated with the use of NSAIDs. Drug Saf. 2004;27:411-20.

https://doi.org/10.2165/00002018-200427060-00005

PMid:15144234 

20. Hanna M, Moon JY. A review of dexketoprofen trometamol in acute pain. Current Medical Research and Opinion. 2019;35:189-202.

https://doi.org/10.1080/03007995.2018.1457016

PMid:29569951 

21. EsparzaVillalpando V, PozosGuillén A, MasuokaIto D, GaitánFonseca C, ChavarríaBolaños D. Analgesic efficacy of preoperative dexketoprofen trometamol: A systematic review and metaanalysis. Drug Dev Res. 2018;79:47-57.

https://doi.org/10.1002/ddr.21419

PMid:29243848 

22. Katz J, Clarke H, Seltzer Z. Preventive analgesia: quo vadimus?. Anesth Analg. 2011;113:1242-53.

https://doi.org/10.1213/ANE.0b013e31822c9a59

PMid:21965352 

23. Mobini A, Mehra P, Chigurupati R. Postoperative Pain and Opioid Analgesic Requirements After Orthognathic Surgery. J Oral Maxillofac Surg. 2018;76:2285-95.

https://doi.org/10.1016/j.joms.2018.05.014

PMid:29886112 

24. Kau CH, Cronin AJ, Richmond S. A three-dimensional evaluation of postoperative swelling following orthognathic surgery at 6 months. Plast Reconstr Surg. 2007;19:2192-9.

https://doi.org/10.1097/01.prs.0000260707.99001.79

PMid:17519721 

25. Eroglu C, Durmus E, Kiresi D. Effect of low-dose dexketoprofen trometamol and paracetamol on postoperative complications after impacted third molar surgery on healthy volunteers: A pilot study. Med Oral Patol Oral y Cir Bucal. 2014;19:e622.

https://doi.org/10.4317/medoral.19835

PMid:25129247 PMCid:PMC4259381

26. Van Der Meer WJ, Dijkstra PU, Visser A, Vissink A, Ren Y. Reliability and validity of measurements of facial swelling with a stereophotogrammetry optical three-dimensional scanner. Br J Oral Maxillofac Surg. 2014;52:922-7.

https://doi.org/10.1016/j.bjoms.2014.08.019

PMid:25219776 

27. Semper-Hogg W, Fuessinger MA, Dirlewanger TW, Cornelius CP, Metzger MC. The influence of dexamethasone on postoperative swelling and neurosensory disturbances after orthognathic surgery: A randomized controlled clinical trial. Head Face Med. 2017;1:1-9.

https://doi.org/10.1186/s13005-017-0153-1

PMid:29116013 PMCid:PMC5678574

28. Lin HH, Kim SG, Kim HY, Niu LS, Lo LJ. Higher dose of dexamethasone does not further reduce facial swelling after orthognathic surgery: A randomized controlled trial using 3-dimensional photogrammetry. Ann Plast Surg. 2017;78:S61-9.

https://doi.org/10.1097/SAP.0000000000001008

PMid:28118231 

29. Jiménez-Martínez E, Gasco-García C, Arrieta-Blanco JJ, Gomez del Torno J. Study of the analgesic efficacy of Dexketoprofen Trometamol 25mg. vs. Ibuprofen 600mg. after their administration in patients subjected to oral surgery. Med oral organo Of la Soc Esp Med Oral y la Acad Iberoam Patol y Med Bucal. 2004;9:143-8.

PMid:14990880