Morais EF, Morais HG, Martins HD, Carlan LM, Costa AL, Freitas RA. Prognostic and clinicopathological significance of tumor-stroma ratio in head and neck squamous cell carcinoma: A systematic review. Med Oral Patol Oral Cir Bucal. 2022 Jul 1;27 (4):e301-9.
doi:10.4317/medoral.24922
https://dx.doi.org/doi:10.4317/medoral.24922
1. Johnson DE, Burtness B, Leemans CR, Lui VWY, Bauman JE, Grandis JR. Head and neck squamous cell carcinoma. Nat Rev Dis Primers. 2020;6:92. |
PMid:33243986 PMCid:PMC7944998 |
2. Eskiizmir G. Tumor microenvironment in head and neck squamous cell carcinomas. Turk Arch Otorhinolaryngol. 2014;53:120-7. |
PMid:29391993 PMCid:PMC5782915 |
3. de Morais EF, Santos HBP, Cavalcante IL, Rabenhorst SHB, Dos Santos JN, Galvão HC, et al. Twist and E-cadherin deregulation might predict poor prognosis in lower lip squamous cell carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol. 2019;127:318-29. |
PMid:30598410 |
4. Woolman M, Tata A, Dara D, Meens J, D'Arcangelo E, Perez CJ, et al. Rapid determination of tumour stroma ratio in squamous cell carcinomas with desorption electrospray ionization mass spectrometry (DESI-MS): A proof-of-concept demonstration. Analyst. 2017;142:3522. |
PMid:28862278 |
5. Peltanova B, Raudenska M, Masarik M. Effect of tumor microenvironment on pathogenesis of the head and neck squamous cell carcinoma: a systematic review. Molecular Cancer. 2019;18:63. |
PMid:30927923 PMCid:PMC6441173 |
6. Zhang XL, Jiang C, Zhang ZX. The tumor-stroma ratio is an independent predictor for survival in nasopharyngeal cancer. Oncol Res Treat. 2014;37:480-84. |
PMid:25231688 |
7. Hirata E, Sahai E. Tumor Microenvironment and Differential Responses to Therapy. Cold Spring Harb Perspect Med. 2017;7:a026781. |
PMid:28213438 PMCid:PMC5495051 |
8. Mascitti M, Zhurakivska K, Togni L, Caponio VCA, Almangush A, Balercia P, et al. Addition of the tumour-stroma ratio to the 8th edition American Joint Committee on Cancer staging system improves survival prediction for patients with oral tongue squamous cell carcinoma. Histopathology. 2020;77:810-22. |
PMid:32633006 |
9. Rani P, Gupta AJ, Mehrol C, Singh M, Khurana N, Passey JC. Clinicopathological correlation of tumor‑stroma ratio and inflammatory cell infiltrate with tumor grade and lymph node metastasis in squamous cell carcinoma of buccal mucosa and tongue in 41 cases with review of literature. J Can Res Ther. 2020;16:445-51. |
PMid:32719249 |
10. Alves A, Diel L, Ramos G. Tumor microenvironment and oral squamous cell carcinoma: A crosstalk between the inflammatory state and tumor cell migration. Oral Oncology. 2021;112:105038. |
PMid:33129055 |
11. van Pelt GW, Krol JA, Lips IM, Peters FP, van Klaveren D, Boonstra JJ, et al. The value of tumor-stroma ratio as predictor of pathologic response after neoadjuvant chemoradiotherapy in esophageal cancer. Clin Transl Radiat Oncol. 2019;20:39-44. |
PMid:31886418 PMCid:PMC6906651 |
12. Wu J, Liang C, Chen M, Su W. Association between tumor-stroma ratio and prognosis in solid tumor patients: a systematic review and meta-analysis. Oncotarget. 2016;7:68954-65. |
PMid:27661111 PMCid:PMC5356603 |
13. Karpathiou G, Vieville M, Gavid M, Camy F, Dumollard JM, Magné N, et al. Prognostic significance of tumor budding, tumor-stroma ratio, cell nests size, and stroma type in laryngeal and pharyngeal squamous cell carcinomas. Head & Neck. 2019;41:1-10. |
PMid:30620425 |
14. Moher D, Liberati A, Tetzlaf J, Altman DG, PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med. 2009;151:264-9. |
PMid:19622511 |
15. Stang A. Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. Eur J Epidemiol. 2010;25:603-5. |
PMid:20652370 |
16. Wang K, Ma W, Wang J. Tumor-stroma ratio is an independent predictor for survival in esophageal squamous cell carcinoma. J Thorac Oncol. 2012;7:1457-61. |
PMid:22843085 |
17. Ünlü M, Çetínayak HO, Önder D, Ecevıt C, Akman F, Ikız AÖ, et al. The prognostic value of tumor-stroma proportion in laryngeal squamous cell carcinoma. Turk Patoloji Derg. 2012;29:27-35. |
PMid:23354793 |
18. Choi JW, Lee D, Hyun SH. Intratumoural heterogeneity measured using FDG PET and MRI is associated with tumour-stroma ratio and clinical outcome in head and neck squamous cell carcinoma. Clin Radiol. 2017;72:482-9. |
PMid:28285707 |
19. Almangush A, Heikkinen I, Bakhti N, Mäkinen LK, Kauppila JH, Pukkila M, et al. Prognostic impact of tumour-stroma ratio in early-stage oral tongue cancers. Histopathology. 2018;72:1128-35. |
PMid:29427291 |
20. Niranjan KC, Sarathy NA. Prognostic impact of tumor-stroma ratio in oral squamous cell carcinoma - A pilot study. Ann Diagn Pathol. 2018;35:56-61. |
PMid:29787931 |
21. Dourado MR, Miwa KYM, Hamada GB, Paranaíba LMR, Sawazaki-Calone Í, Domingueti CB, et al. Prognostication for oral squamous cell carcinoma patients based on the tumour-stroma ratio and tumour budding. Histopathology. 2020;76:906-18. |
PMid:31984527 |
22. Giraldo NA, Sanchez-Salas R, Peske JD, Vano Y, Becht E, Petitprez F, et al. The clinical role of the TME in solid cancer. Br J Cancer. 2019;120:45-53. |
PMid:30413828 PMCid:PMC6325164 |
23. Almangush A, Bello IO, Heikkinen I, Hagström J, Haglund C, Kowalski LP, et al. Stromal categorization in early oral tongue cancer. Virchows Archiv. 2021; 478:925-32. |
PMid:32955604 PMCid:PMC8099799 |
24. van Pelt GW, Kjær-Frifeldt S, van Krieken JHJM, Al Dieri R, Morreau H, Tollenaar RAEM, et al. Scoring the Tumor-Stroma Ratio in Colon Cancer: Procedure and Recommendations. Virchows Arch. 2018;473:405-12. |
PMid:30030621 PMCid:PMC6182321 |
25. Bello IO, Wennerstrand PM, Suleymanova I, Siponen M, Qannam A, Nieminen P, et al. Biopsy quality is essential for preoperative prognostication in oral tongue cancer. APMIS. 2021;129:118-27. |
PMid:33320967 |
26. Mesker WE, Junggeburt JM, Szuhai K, de Heer P, Morreau H, Tanke HJ, et al. The carcinoma-stromal ratio of colon carcinoma is an independent factor for survival compared to lymph node status and tumor stage. Cell Oncol. 2007;5:387-98. |
PMid:17726261 PMCid:PMC4617992 |
27. Gujam FJ, Edwards J, Mohammed ZM, Going JJ, McMillan DC. The relationship between the tumour stroma percentage, clinicopathological characteristics and outcome in patients with operable ductal breast cancer. Br J Cancer. 2014;111:157‑65. |
PMid:24874480 PMCid:PMC4090742 |
28. Downey CL, Thygesen HH, Sharma N, Shaaban AM. Prognostic significance of tumour stroma ratio in inflammatory breast cancer. Springerplus. 2015;4:68. |
PMid:25713761 PMCid:PMC4334919 |
29. Panayiotou H, Orsi NM, Thygesen HH, Wright AI, Winder M, Hutson R, et al. The prognostic significance of tumour‑stroma ratio in endometrial carcinoma. BMC Cancer. 2015;15:955. |
PMid:26674153 PMCid:PMC4682261 |
30. Chen Y, Zhang L, Liu W, Liu X. Prognostic significance of the tumor‑stroma ratio in epithelial ovarian cancer. Biomed Res Int. 2015;2015:589301. |
PMid:26609529 PMCid:PMC4644548 |
31. Liu J, Liu J, Li J, Chen Y, Guan X, Wu X, et al. Tumor‑stroma ratio is an independent predictor for survival in early cervical carcinoma. Gynecol Oncol. 2014;132:81‑6. |
PMid:24219981 |
32. Lv Z, Cai X, Weng X, Xiao H, Du C, Cheng J, et al. Tumor‑stroma ratio is a prognostic factor for survival in hepatocellular carcinoma patients after liver resection or transplantation. Surgery. 2015;158:142‑50. |
PMid:25890776 |
33. Brooks JM, Menezes AN, Ibrahim M, Archer L, Lal N, Bagnall CJ, et al. Development and validation of a combined hypoxia and immune prognostic classifier for head and neck cancer. Clin Cancer Res. 2019;25:5315-28. |
PMid:31182433 |