Tancredi-Cueto N, Vigil-Bastitta G, Bologna-Molina R, Beovide‑Cortegoso V. The value of Phosphohistone H3 as a cell proliferation marker in oral squamous cell carcinoma. A comparative study with Ki-67 and the mitotic activity index. Med Oral Patol Oral Cir Bucal. 2022 Sep 1;27 (5):e444-51.
doi:10.4317/medoral.25420
https://dx.doi.org/doi:10.4317/medoral.25420
1. Speight PM, Farthing PM. The pathology of oral cancer. Br Dent J. 2018;225:841-7. |
PMid:30412536 |
2. Almangush A, Mäkitie AA, Triantafyllou A, de Bree R, Strojan P, Rinaldo A, et al. Staging and grading of oral squamous cell carcinoma: An update. Oral Oncol. 2020;107:104799. |
PMid:32446214 |
3. Lopes VKM, de Jesus AS, de Souza LL de, Miyahara LAN, Guimarães DM, Pontes HAR, et al. Ki-67 protein predicts survival in oral squamous carcinoma cells: an immunohistochemical study. Braz Oral Res. 2017;31:e66. |
PMid:28832714 |
4. Gadbail AR, Sarode SC, Chaudhary MS, Gondivkar SM, Tekade SA, Yuwanati M, et al. Ki67 labelling index predicts clinical outcome and survival in oral squamous cell carcinoma. J Appl Oral Sci. 2021;29:1-10. |
PMid:33656066 PMCid:PMC7934280 |
5. Gioacchini FM, Alicandri-Ciufelli M, Kaleci S, Magliulo G, Presutti L, Re M. The prognostic value of cyclin D1 expression in head and neck squamous cell carcinoma. Eur Arch Oto-Rhino-Laryngology. 2016;273:801-9. |
PMid:25516222 |
6. Marangon Junior H, Leão PLR, Melo VVM, Caixeta ÂB, Souza PEA, de Aguiar MCF, et al. Cell proliferation is associated with intensity of tumor budding in oral squamous cell carcinoma. J Oral Pathol Med. 2018;47:128-35. |
PMid:29052910 |
7. Chitra NS, Boaz K, Srikant N, Lewis AJ, Sneha KS. Pattern-corrected mitotic activity index (PMAI): A novel prognosticator of oral squamous cell carcinoma. Turk Patoloji Derg. 2020;36:31-8. |
PMid:31310321 |
8. Blatt S, Krüger M, Ziebart T, Sagheb K, Schiegnitz E, Goetze E, et al. Biomarkers in diagnosis and therapy of oral squamous cell carcinoma : A review of the literature. J Cranio-Maxillofacial Surg. 2017;45:722-30. |
PMid:28318929 |
9. Kim JY, Sook Jeong H, Chung T, Kim M, Hee Lee J, Hee Jung W, et al. The value of phosphohistone H3 as a proliferation marker for evaluating invasive breast cancers: A comparative study with Ki67. Oncotarget. 2017;8:65064-76. |
PMid:29029412 PMCid:PMC5630312 |
10. van Steenhoven JEC, Kuijer A, Kornegoor R, van Leeuwen G, van Gorp J, van Dalen T, et al. Assessment of tumour proliferation by use of the mitotic activity index, and Ki67 and phosphohistone H3 expression, in early-stage luminal breast cancer. Histopathology. 2020;77:579-87. |
PMid:32557844 PMCid:PMC7539961 |
11. Elmaci I, Altinoz MA, Sari R, Bolukbasi FH. Phosphorylated Histone H3 (PHH3) as a Novel Cell Proliferation Marker and Prognosticator for Meningeal Tumors: A Short Review. Appl Immunohistochem Mol Morphol. 2018;26:627-31. |
PMid:28777144 |
12. Dias EP, Oliveira NSC, Serra-Campos AO, da Silva AKF, da Silva LE, Cunha KS. A novel evaluation method for Ki-67 immunostaining in paraffin-embedded tissues. Virchows Arch. 2021;479:121-31. |
PMid:33464376 |
13. Takkem A, Barakat C, Zakaraia S, Zaid K, Najmeh J, Ayoub M, et al. Ki-67 prognostic value in different histological grades of oral epithelial dysplasia and oral squamous cell carcinoma. Asian Pacific J Cancer Prev. 2018;19:3279-86. |
PMid:30486632 PMCid:PMC6318382 |
14. Sales Gil R, Vagnarelli P. Ki-67: More Hidden behind a 'Classic Proliferation Marker'. Trends Biochem Sci. 2018;43:747-8. |
PMid:30131191 |
15. Xie S, Liu Y, Qiao X, Hua RX, Wang K, Shan XF, et al. What is the prognostic significance of Ki-67 positivity in oral squamous cell carcinoma?. J Cancer. 2016;7:758 67. |
PMid:27162533 PMCid:PMC4860791 |
16. Lai CPT, Yeong JPS, Tan A Sen, Ong CHC, Lee B, Lim JCT, et al. Evaluation of phospho-histone H3 in Asian triple-negative breast cancer using multiplex immunofluorescence. Breast Cancer Res Treat. 2019;178:295-305. |
PMid:31410680 |
17. Yang H, Jin X, Dan H, Chen Q. Histone modifications in oral squamous cell carcinoma and oral potentially malignant disorders. Oral Dis. 2020;26:719-32. |
PMid:31056829 |
18. Khieu ML, Broadwater DR, Aden JK, Coviello JM, Lynch DT, Hall JM. The Utility of Phosphohistone H3 (PHH3) in Follicular Lymphoma Grading: A Comparative Study with Ki-67 and H&E Mitotic Count. Am J Clin Pathol. 2019;151:542-50. |
PMid:30788495 |
19. Bedekovics J, Irsai G, Hegyi K, Beke L, Krenács L, Gergely L, et al. Mitotic Index Determined by Phosphohistone H3 Immunohistochemistry for Precise Grading in Follicular Lymphoma. Appl Immunohistochem Mol Morphol. 2018;26:579-85. |
PMid:27997502 |
20. Van Diest PJ, Brugal G, Baak JPA. Proliferation markers in tumours: Interpretation and clinical value. J Clin Pathol. 1998;51:716-24. |
PMid:10023332 PMCid:PMC500923 |
21. Ohashi R, Namimatsu S, Sakatani T, Naito Z, Takei H, Shimizu A. Prognostic utility of atypical mitoses in patients with breast cancer: A comparative study with Ki67 and phosphohistone H3. J Surg Oncol. 2018;118:557-67. |
PMid:30098295 |
22. Jing YUE, Zhou Q, Zhu H, Zhang YE, Song Y, Zhang X. Ki ‑ 67 is an independent prognostic marker for the recurrence and relapse of oral squamous cell carcinoma. Oncol Lett. 2019;17:974-80. |
PMid:30655856 |
23. Cortegoso AVB, Laureano NK, Silva AD da, Danilecviz CK, Magnusson AS, Visioli F, et al. Cell proliferation markers at the invasive tumor front of oral squamous cell carcinoma: comparative analysis in relation to clinicopathological parameters of patients. J Appl Oral Sci. 2017;25:318-23. |
PMid:28678951 PMCid:PMC5482255 |
24. Oliveira ML, Wagner V, Sant'ana Filho M, Carrard V, Hugo F, Martins M. A 10-year analysis of the oral squamous cell carcinoma profile in patients from public health centers in Uruguay. Braz Oral Res. 2015;29:1-8. |
PMid:26083090 |
25. Hao Q, Dai C, Deng Y, Xu P, Tian T, Lin S, et al. Pooling analysis on prognostic value of PHH3 expression in cancer patients. Cancer Manag Res. 2018;10:2279-88. |
PMid:30104898 PMCid:PMC6071623 |
26. Bhuyan L, Sarangi S, Das BK, Das SN, Nayak S. Proliferative index in invasive tumor front of oral squamous cell carcinoma: A potential prognostic indicator. J Contemp Dent Pract. 2018;19:170-6. |
PMid:29422466 |
27. Brockton NT, Lohavanichbutr P, Enwere EK, Upton MP, Kornaga EN, Nakoneshny SC, et al. Impact of tumoral carbonic anhydrase IX and Ki ‑ 67 expression on survival in oral squamous cell carcinoma patients. Oncol Lett. 2017;14:5434-42. |
PMid:29098033 PMCid:PMC5652251 |
28. Gonzalez-Moles MA, Ruiz-Avila I, Gil-Montoya JA, Esteban F, Bravo M. Analysis of Ki-67 expression in oral squamous cell carcinoma: Why Ki-67 is not a prognostic indicator. Oral Oncol. 2010;46:525-30. |
PMid:20400362 |
29. Lea D, Gudlaugsson EG, Skaland I, Lillesand M, Søreide K, Søreide JA. Digital Image Analysis of the Proliferation Markers Ki67 and Phosphohistone H3 in Gastroenteropancreatic Neuroendocrine Neoplasms: Accuracy of Grading Compared with Routine Manual Hot Spot Evaluation of the Ki67 Index. Appl Immunohistochem Mol Morphol. 2021;29:499-505. |
PMid:33758143 PMCid:PMC8354564 |