Erazo-Puentes MC, Sánchez-Torres A, Aguirre-Urizar JM, Bara-Casaus J, Gay-Escoda C. Has the 8th American joint committee on cancer TNM staging improved prognostic performance in oral cancer? A systematic review. Med Oral Patol Oral Cir Bucal. 2024 Mar 1;29 (2):e161-71.
doi:10.4317/medoral.25983
https://dx.doi.org/doi:10.4317/medoral.25983
1. Shield KD, Ferlay J, Jemal A, Sankaranarayanan R, Chaturvedi AK, Bray F, et al. The global incidence of lip, oral cavity, and pharyngeal cancers by subsite in 2012. CA Cancer J Clin. 2017;67:51-64. |
PMid:28076666 |
2. Ferlay J, Colombet M, Soerjomataram I, Dyba T, Randi G, Bettio M, et al. Cancer incidence and mortality patterns in Europe: Estimates for 40 countries and 25 major cancers in 2018. Eur J Cancer. 2018;103:356-87. |
PMid:30100160 |
3. Kato MG, Baek C-H, Chaturvedi P, Gallagher R, Kowalski LP, Leemans CR, et al. Update on oral and oropharyngeal cancer staging - International perspectives. World J Otorhinolaryngol - Head Neck Surg. 2020;6:66-75. |
PMid:32426706 PMCid:PMC7221211 |
4. Rivera C. Essentials of oral cancer. Int J Clin Exp Pathol. 2015;8:11884-94. |
PMid:26617944 |
5. Ridge JA, Lydiatt WM, Patel SG, Glastonbury CM, Brandwein-Gensler M, Ghossein RA, Shah JP. Oral cavity. In: Amin MB, editor. AJCC cancer staging manual 8th ed. Chicago: Springer. 2017;79-101. |
PMid: |
6. Takes RP, Rinaldo A, Silver CE, Piccirillo JF, Haigentz M, Suárez C, et al. Future of the TNM classification and staging system in head and neck cancer. Head Neck. 2010;32:1693-711. |
PMid:20191627 |
7. Huang SH, O'Sullivan B. Overview of the 8th edition TNM classification for head and neck cancer. Curr Treat Options Oncol. 2017;18:40. |
PMid:28555375 |
8. Kozak MM, Shah J, Chen M, Schaberg K, von Eyben R, Chen JJ, et al. Depth of invasion alone as a prognostic factor in low-risk early-stage oral cavity carcinoma. Laryngoscope. 2019;129:2082-86. |
PMid:30604435 |
9. Suton P, Salaric I, Granic M, Mueller D, Luksic I. Prognostic significance of extracapsular spread of lymph node metastasis from oral squamous cell carcinoma in the clinically negative neck. Int J Oral Maxillofac Surg. 2017;46:669-75. |
PMid:28347602 |
10. Moher D, Liberati A, Tetzlaff J, Altman DG, PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement. Int J Surg. 2010;8:336-41. |
PMid:20171303 |
11. Wells GA, Shea B, O'Connell D, Peterson J, Welch V, Tugwell P. The Newcastle‐Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta‐analyses. 3rd Symposium on Systematic Reviews: Beyond the Basics, July 2000; Oxford, UK. |
PMid: |
12. Liao CT, Lee LY, Hsueh C, Lin CY, Fan KH, Wang HM, et al. Clinical outcomes in pT4 tongue carcinoma are worse than in pT3 Disease: How extrinsic muscle invasion should be considered?. Ann Surg Oncol. 2017;24:2570-9. |
PMid:28577181 |
13. Liao CT, Lee LY, Hsueh C, Lin CY, Fan KH, Wang HM, et al. Pathological risk factors stratification in pN3b oral cavity squamous cell carcinoma: Focus on the number of positive nodes and extranodal extension. Oral Oncol. 2018;86:188-94. |
PMid:30409299 |
14. Liao CT, Lee LY, Hsueh C, Lin CY, Fan KH, Wang HM, et al. Tumor depth of invasion (tumor > 4 cm/depth > 10 mm and depth > 20 mm) and through cortex/skin invasion are both valid criteria for classifying tumors as pT4a in AJCC 2018 oral cavity cancer staging system. Ann Surg Oncol. 2019;26:3663-72. |
PMid:31264118 |
15. Moeckelmann N, Ebrahimi A, Dirven R, Liu J, Low THH, Gupta R, et al. Analysis and comparison of the 8th edition american joint committee on cancer (AJCC) nodal staging system in cutaneous and oral squamous cell cancer of the head and neck. Ann Surg Oncol. 2018;25:1730-6. |
PMid:29352431 |
16. Moeckelmann N, Ebrahimi A, Tou YK, Gupta R, Low THH, Ashford B, et al. Prognostic implications of the 8th edition american joint committee on cancer (AJCC) staging system in oral cavity squamous cell carcinoma. Oral Oncol. 2018;85:82-6. |
PMid:30220324 |
17. Subramaniam N, Clark JR, Goldstein D, de Almeida J, Ali Abdalaty AH, Balasubramanian D, et al. Stage pN3a in oral cancer: A redundant entity?. Oral Oncol. 2020;110:104815. |
PMid:32467072 |
18. Dhar H, Agarwal J. Depth of invasion in early oral cancers: is it an independent prognostic factor?. J Clin Oncol. 2019;37:6058. |
PMid:33814237 |
19. Harada H, Tomioka H, Yokokawa M, Nojima H, Komiya R, Kayamori K, et al. Depth of invasion (DOI) introduced in uicc 8th T classification in tongue carcinoma-evaluation of histopathological DOI and clinical DOI in consideration of shrinkage rate of the specimen. Japanese J Head Neck Cancer. 2019;45:1-7. |
PMid: |
20. Hirshoren N, Weinberger JM, Eliashar R. Head and neck malignancies classification, the 8th edition of the american joint committee on cancer - What is new?. Harefuah. 2020;159:132-6. |
PMid:32048495 |
21. Almangush A, Mäkitie AA, Mäkinen LK, Kauppila JH, Pukkila M, Hagström J, et al. Small oral tongue cancers (≤ 4 cm in diameter) with clinically negative neck: from the 7th to the 8th edition of the american joint committee on cancer. Virchows Arch. 2018;473:481-7. |
PMid:30039390 |
22. Almangush A, Salo T. The 8th Edition of the American Joint Committee on Cancer (AJCC8) Staging Manual: any improvement in the prognostication of oral tongue cancer? Chin Clin Oncol. 2019;8:S8. |
PMid:30691272 |
23. Dang RR, Qureshi MM, Caldroney SJ, Salama AR, Truong MT. Recategorization of tumor stage in patients with node-negative oral tongue cancer: Impact of the eighth edition american joint committee staging system. Head Neck. 2019;41:2976-82. |
PMid:31025799 |
24. Dirven R, Ebrahimi A, Moeckelmann N, Palme CE, Gupta R, Clark J. Tumour thickness versus depth of invasion - Analysis of the 8th edition american joint committee on cancer staging for oral cancer. Oral Oncol. 2017;74:30-33. |
PMid:29103748 |
25. Farquhar DR, Coniglio AJ, Masood MM, Lenze N, Brennan P, Anantharaman D, et al. Evaluation of pathologic staging using number of nodes in p16-negative head and neck cancer. Oral Oncol. 2020;108:104800. |
PMid:32492516 PMCid:PMC7483879 |
26. García J, López M, López L, Bagué S, Granell E, Quer M, et al. Validation of the pathological classification of lymph node metastasis for head and neck tumors according to the 8th edition of the TNM classification of malignant tumors. Oral Oncol. 2017;70:29-33. |
PMid:28622888 |
27. Jain D, Dravid C, Singla A, Kumari S, Grover RK. Comparison of the seventh and eighth editions of the american joint committee on cancer pT and pN classifications as predictors of survival in patients with oral squamous cell carcinoma. Am J Clin Pathol. 2019;151:292-301. |
PMid:30383186 |
28. Mattavelli D, Ferrari M, Taboni S, Morello R, Paderno A, Rampinelli V, et al. The 8th TNM classification for oral squamous cell carcinoma: What is gained, what is lost, and what is missing. Oral Oncol. 2020;111:104937. |
PMid:32750558 |
29. Almangush A, Pirinen M, Youssef O, Mäkitie AA, Leivo I. Risk stratification in oral squamous cell carcinoma using staging of the eighth american joint committee on cancer: Systematic review and meta-analysis. Head Neck. 2020;42:3002-17. |
PMid:32548858 |
30. Riju J, George NA, Krishna J. AJCC 8th versus AJCC 7th as a prognostic indicator in buccal mucosal squamous cell carcinoma. Indian J Surg Oncol. 2020;14:228-33. |
PMid:36891445 |
31. McGoldrick DM, Torres-Rendon A, Sandhu R, Walton G. Validation of the UICC 8th edition staging of oral cavity squamous cell carcinoma in a UK cohort. Br J Oral Maxillofac Surg. 2021;59:76-81. |
PMid:33082012 |
32. Jawad H, Ashaari SS, O'Shea R, Callanan D, Sheahan P, Feeley L. Prognostic performance of TNM8 staging rules in oral cavity squamous cell carcinoma. Oral Oncol. 2020;111:105021. |
PMid:33011675 |
33. Sambasivan K, Sassoon I, Thavaraj S, Kennedy R, Doss G, Michaelidou A, et al. TNM 8 staging is a better prognosticator than TNM 7 for patients with locally advanced oral cavity squamous cell carcinoma treated with surgery and post-operative radiotherapy. Radiother Oncol. 2021;160:54-60. |
PMid:33845044 |
34. McGoldrick DM, Torres-Rendon A, Sandhu R, Walton G. Validation of the UICC 8th edition staging of oral cavity squamous cell carcinoma in a UK cohort. Br J Oral Maxillofac Surg. 2021;59:76-81. |
PMid:33082012 |
35. Amit M, Tam S, Takahashi H, Choi KY, Zafereo M, Bell D, et al. Prognostic performance of the American Joint Committee on Cancer 8th edition of the TNM staging system in patients with early oral tongue cancer. Head Neck. 2019;41:1270-6. |
PMid:30537405 |
36. Boeve K, Melchers LJ, Schuuring E, Roodenburg JL, Halmos GB, van Dijk BA, et al. Addition of tumour infiltration depth and extranodal extension improves the prognostic value of the pathological TNM classification for early-stage oral squamous cell carcinoma. Histopathology. 2019;75:329-37. |
PMid:31021008 PMCid:PMC6851684 |
37. Cramer JD, Reddy A, Ferris RL, Duvvuri U, Samant S. Comparison of the seventh and eighth edition american joint committee on cancer oral cavity staging systems. Laryngoscope. 2018;128:2351-60. |
PMid:29658104 |
38. Kano S, Sakashita T, Tsushima N, Mizumachi T, Nakazono A, Suzuki T, et al. Validation of the 8th edition of the AJCC/UICC TNM staging system for tongue squamous cell carcinoma. Int J Clin Oncol. 2018;23:844-50. |
PMid:29675646 |
39. Lee NCJ, Eskander A, Park HS, Mehra S, Burtness BA, Husain Z. Pathologic staging changes in oral cavity squamous cell carcinoma: Stage migration and implications for adjuvant treatment. Cancer. 2019;125:2975-83. |
PMid:31090934 |
40. Mascitti M, Rubini C, De Michele F, Balercia P, Girotto R, Troiano G, et al. American Joint Committee on Cancer staging system 7th edition versus 8th edition: any improvement for patients with squamous cell carcinoma of the tongue?. Oral Surg Oral Med Oral Pathol Oral Radiol. 2018;126:415-23. |
PMid:30217459 |
41. Matos LL, Dedivitis RA, Kulcsar MAV, de Mello ES, Alves VAF, Cernea CR. External validation of the AJCC Cancer Staging Manual, 8th edition, in an independent cohort of oral cancer patients. Oral Oncol. 2017;71:47-53. |
PMid:28688690 |
42. Murthy S, Low T-HH, Subramaniam N, Balasubramanian D, Sivakumaran V, Anand A, et al. Validation of the eighth edition AJCC staging system in early T1 to T2 oral squamous cell carcinoma. J Surg Oncol. 2019;119:449-54. |
PMid:30575027 |
43. Pollaers K, Hinton-Bayre A, Friedland PL, Farah CS. AJCC 8th edition oral cavity squamous cell carcinoma staging - is it an improvement on the AJCC 7th edition?. Oral Oncol. 2018;82:23-8. |
PMid:29909897 |
44. Singhavi HR, Chakrabarti S, Singh A, Mair M, Bhattacharjee A, Shetty R, et al. Comparison of the seventh and eighth editions american joint committee cancer classification system in oral cavity squamous cell cancers. Int J Cancer. 2020;146:3379-84. |
PMid:31583706 |
45. Subramaniam N, Murthy S, Balasubramanian D, Low T-HH, Vidhyadharan S, Clark JR, et al. Adverse pathologic features in T1/2 oral squamous cell carcinoma classified by the american joint committee on cancer eighth edition and implications for treatment. Head Neck. 2018;40:2123-28. |
PMid:30102804 |
46. Tirelli G, Gatto A, Boscolo Nata F, Bussani R, Piccinato A, Marcuzzo AV, et al. Prognosis of oral cancer: A comparison of the staging systems given in the 7th and 8th editions of the American Joint Committee on Cancer Staging Manual. Br J Oral Maxillofac Surg. 2018;56:8-13. |
PMid:29198482 |
47. Vuity D, McMahon J, Takhiuddin S, Slinger C, McLellan D, Wales C, et al. Is the 8th edition of the union for international cancer control staging of oral cancer good enough?. Br J Oral Maxillofac Surg. 2018;56:272-7. |
PMid:29576230 |
48. Ebrahimi A, Gil Z, Amit M, Yen TC, Liao CT, Chaturvedi P, et al. Primary tumour staging for oral cancer and a proposed modification incorporating depth of invasion: An international multicenter retrospective study. JAMA Otolaryngol Head Neck Surg. 2014;140:1138-48. |
PMid:25075712 |
49. Shaw RJ, Lowe D, Woolgar JA, Brown JS, Vaughan ED, Evans C, et al. Extracapsular spread in oral squamous cell carcinoma. Head Neck. 2010;32:714-22. |
PMid:19827119 |
50. Wreesmann VB, Katabi N, Palmer FL, Montero PH, Migliacci JC, Gonen M, et al. Influence of extracapsular nodal spread extent on prognosis of oral squamous cell carcinoma. Head Neck. 2016;38:1192-9. |
PMid:26514096 PMCid:PMC4996672 |