Oliveira FM, Borges MM, Malta CE, Moura JF, Forte CP, Barbosa JV, et al. Comparison of a daily and alternate-day photobiomodulation protocol in the prevention of oral mucositis in patients undergoing radiochemotherapy for oral cancer: a triple-blind, controlled clinical trial. Med Oral Patol Oral Cir Bucal. 2024 May 1;29 (3):e430-40.


doi:10.4317/medoral.26436

https://dx.doi.org/doi:10.4317/medoral.26436


1. Bessell A, Glenny AM, Furness S, Clarkson JE, Oliver R, Conway DI, Macluskey M, Pavitt S, Sloan P, Worthington HV. Interventions for the treatment of oral and oropharyngeal cancers: surgical treatment. Cochrane Database Syst Rev. 2011;9:CD006205.

https://doi.org/10.1002/14651858.CD006205.pub3

PMid:21901703 PMCid:PMC7144736

2. Huang SH, O'Sullivan B. Oral cancer: Current role of radiotherapy and chemotherapy. Med Oral Patol Oral Cir Bucal. 2013;18:233-40.

https://doi.org/10.4317/medoral.18772

PMid:23385513 PMCid:PMC3613874

3. Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, et al. Incidência e mortalidade por câncer em todo o mundo: fontes, métodos e principais padrões no GLOBOCAN 2012. Int J Cancer. 2015;136:359-86.

https://doi.org/10.1002/ijc.29210

PMid:25220842 

4. Langendijk JA. New developments in radiotherapy of head and neck cancer: higher precision with less patient discomfort? Radiother Oncol. 2007;85:1-6.

https://doi.org/10.1016/j.radonc.2007.07.019

PMid:17854932 

5. Carroll WR, Locher JL, Canon CL, Bohannon IA, McColloch NL, Magnuson JS. Pretreatment swallowing exercises improve swallow function after chemoradiation. Laryngoscope. 2008;118:39-43.

https://doi.org/10.1097/MLG.0b013e31815659b0

PMid:17989581 

6. Bourbonne V, Otz J, Bensadoun RJ, Dissaux G, Lucia F, Leclere JC, et al. Radiotherapy mucositis in head and neck cancer: prevention by low-energy surface laser. BMJ Support Palliat Care. 2022;12:838-45.

https://doi.org/10.1136/bmjspcare-2019-001851

PMid:31527154 

7. Elad S, Ackerstein A, Bitan M, Shapira MY, Resnick I, Gesundheit B, et al. A prospective, double-blind phase II study evaluating the safety and efficacy of a topical histamine gel for the prophylaxis of oral mucositis in patients post hematopoietic stem cell transplantation. Bone Marrow Transplant. 2006; 37:757-62.

https://doi.org/10.1038/sj.bmt.1705331

PMid:16518424 

8. Sonis ST. New thoughts on the initiation of mucositis. Oral Dis. 2010;16:597-600.

https://doi.org/10.1111/j.1601-0825.2010.01681.x

PMid:20846150 

9. Gandemer V, Le Deley MC, Dollfus C, Auvrignon A, Bonnaure-Mallet M, Duval M, De Lumley L, et al. Pain task force of the SFCE. Multicenter randomized trial of chewing gum for preventing oral mucositis in children receiving chemotherapy. J Pediatr Hematol Oncol. 2007;29:86-94.

https://doi.org/10.1097/MPH.0b013e318030a3e4

PMid:17279004 

10. Campos TM, do Prado Tavares Silva CA, Sobral APT, Sobral SS, Rodrigues MFSD, Bussadori SK, et al. Photobiomodulation in oral mucositis in patients with head and neck cancer: a systematic review and meta-analysis followed by a cost-effectiveness analysis. Support Care Cancer. 2020;28:5649-59.

https://doi.org/10.1007/s00520-020-05613-8

PMid:32666214 

11. Lins RD, Dantas EM, Lucena KC, Catão MH, Granville-Garcia AF, Carvalho Neto LG. Biostimulation effects of low-power laser in the repair process. An Bras Dermatol. 2010;85:849-55.

https://doi.org/10.1590/S0365-05962010000600011

PMid:21308309 

12. Kuhn-Dall'Magro A, Zamboni E, Fontana T, Dogenski LC, De Carli JP, Dall'Magro E, Fornari F. Low-level Laser Therapy in the Management of Oral Mucositis Induced by Radiotherapy: A Randomized Double-blind Clinical Trial. J Contemp Dent Pract. 2022;23:31-6.

https://doi.org/10.5005/jp-journals-10024-3277

PMid:35656654 

13. Campos TM, Prado Tavares Silva CA, Sobral APT, Sobral SS, Rodrigues MFSD, Bussadori SK, et al. Photobiomodulation in oral mucositis in patients with head and neck cancer: a systematic review and meta-analysis followed by a cost-effectiveness analysis. Support Care Cancer. 2020;28:5649-59.

https://doi.org/10.1007/s00520-020-05613-8

PMid:32666214 

14. Antunes HS, Herchenhorn D, Small IA, Araújo CM, Viégas CM, Cabral E, et al. Phase III trial of low-level laser therapy to prevent oral mucositis in head and neck cancer patients treated with concurrent chemoradiation. Radiother Oncol. 2013;109:297-302.

https://doi.org/10.1016/j.radonc.2013.08.010

PMid:24044799 

15. Martins AFL, Nogueira TE, Morais MO, Oton-Leite AF, Valadares MC, Batista AC, et al. Effect of photobiomodulation on the severity of oral mucositis and molecular changes in head and neck cancer patients undergoing radiotherapy: a study protocol for a cost-effectiveness randomized clinical trial. Trials. 2019;20:97.

https://doi.org/10.1186/s13063-019-3196-8

PMid:30709370 PMCid:PMC6359861

16. Navazesh M, Kumar SK; University of Southern California School of Dentistry. Measuring salivary flow: challenges and opportunities. J Am Dent Assoc. 2008;139:35S-40S

https://doi.org/10.14219/jada.archive.2008.0353

PMid:18460678 

17. Volpato LE, Silva TC, Oliveira TM, Sakai VT, Machado MA. Radiation therapy and chemotherapy-induced oral mucositis. Braz J Otorhinolaryngol. 2007;4:562-8.

https://doi.org/10.1016/S1808-8694(15)30110-5

PMid:17923929 

18. Gonzalez M, Borges LM, Silveira DH, Assunção MCF, Orlandi SP. Cristina et al. Validation of the Portuguese version of the subjective global assessment produced by the patient. Rev Bras Nutr Clin. 2010;25:102-8.

PMid:

19. Pignon JP, le Maître A, Maillard E, Bourhis J; MACH-NC Collaborative Group. Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): an update on 93 randomised trials and 17,346 patients. Radiother Oncol. 2009;92:4-14.

https://doi.org/10.1016/j.radonc.2009.04.014

PMid:19446902 

20. Caillot E. Mucites radio-induites buccopharyngées : actualités sur la prise en charge. Cancer/Radiothérapie. 2012;16:358-63.

https://doi.org/10.1016/j.canrad.2012.05.005

PMid:22841560 

21. González Ferreira JA, Jaén Olasolo J, Azinovic I, Jeremic B. Effect of radiotherapy delay in overall treatment time on local control and survival in head and neck cancer: Review of the literature. Rep Pract Oncol Radiother. 2015;20:328-39.

https://doi.org/10.1016/j.rpor.2015.05.010

PMid:26549990 PMCid:PMC4597087

22. Barros-Silva PG, Fontes-Borges MM, Costa-Dias C, Mota-Lemos JV, Socorro-Saldanha-Cunha MD, Fernandes-Souza E, et al. Clinical-pathological and sociodemographic factors associated with the distant metastasis and overall survival of oral cavity and oropharynx squamous cell carcinoma. Med Oral Patol Oral Cir Bucal. 2020;25:375-82.

https://doi.org/10.4317/medoral.23410

PMid:32271320 PMCid:PMC7211363

23. Dantas TS, de Barros Silva PG, Sousa EF, da Cunha MDP, de Aguiar ASW, Costa FWG, et al.Influence of Educational Level, Stage, and Histological Type on Survival of Oral Cancer in a Brazilian Population: A Retrospective Study of 10 Years Observation. Medicine (Baltimore). 2016;95:2314.

https://doi.org/10.1097/MD.0000000000002314

PMid:26817864 PMCid:PMC4998238

24. Hahn WC, Weinberg RA. Rules for making human tumor cells. N Engl J Med. 2002;14:1593-603.

https://doi.org/10.1056/NEJMra021902

PMid:12432047 

25. Shavi GR, Thakur B, Bhambal A, Jain S, Singh V, Shukla A. Oral Health Related Quality of Life in Patients of Head and Neck Cancer Attending Cancer Hospital of Bhopal City, India. J Int Oral Health. 2015;7:21-7.

PMID: 26464534

26. Kusiak A, Jereczek-Fossa BA, Cichońska D, Alterio D. Oncological-Therapy Related Oral Mucositis as an Interdisciplinary Problem-Literature Review. Int J Environ Res Public Health. 2020;17:2464.

https://doi.org/10.3390/ijerph17072464

PMid:32260309 PMCid:PMC7177874

27. Nitschke I, Müller F. The impact of oral health on the quality of life in the elderly. Oral Health Prev Dent. 2004;2:271-5.

PMid:15646585

28. Westgaard KL, Hynne H, Amdal CD, et al. Oral and ocular late effects in head and neck cancer patients treated with radiotherapy. Sci Rep 2021;1:4026.

https://doi.org/10.1038/s41598-021-83635-w

PMid:33597629 PMCid:PMC7889862

29. Russi EG, Raber-Durlacher JE, Sonis ST. Local and systemic pathogenesis and consequences of regimen-induced inflammatory responses in patients with head and neck cancer receiving chemoradiation. Mediators Inflamm. 2014;2014:518261.

https://doi.org/10.1155/2014/518261

PMid:24757285 PMCid:PMC3976778