Alves GMTT, Severino-Lazo RJG, Amaral-Silva GK, Silveira FMM, Carvalho MV. DNA mismatch repair system expression in salivary gland tumors: A Systematic Review. Med Oral Patol Oral Cir Bucal. 2024 Sep 1;29 (5):e655-64.


doi:10.4317/medoral.26647

https://dx.doi.org/doi:10.4317/medoral.26647


1. Alsanie I, Rajab S, Cottom H, Adegun O, Agarwal R, Jay A, et al. Distribution and Frequency of Salivary Gland Tumours: An International Multicenter Study. Head Neck Pathol. 2022;16:1043-54.

https://doi.org/10.1007/s12105-022-01459-0

PMid:35622296 PMCid:PMC9729635

2. Fonseca FP, Carvalho Mde V, de Almeida OP, Rangel AL, Takizawa MC, Bueno AG, et al. Clinicopathologic analysis of 493 cases of salivary gland tumors in a Southern Brazilian population. Oral Surg Oral Med Oral Pathol Oral Radiol. 2012;114:230-9.

https://doi.org/10.1016/j.oooo.2012.04.008

PMid:22769409 

3. Skálová A, Hyrcza MD, Leivo I. Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Salivary Glands. Head Neck Pathol. 2022;16:40-53.

https://doi.org/10.1007/s12105-022-01420-1

PMid:35312980 PMCid:PMC9018948

4. Schvartsman G, Pinto NA, Bell D, Ferrarotto R. Salivary gland tumors: Molecular characterization and therapeutic advances for metastatic disease. Head Neck. 2019;41:239-47.

https://doi.org/10.1002/hed.25468

PMid:30552848 

5. Fonseca FP, Sena Filho M, Altemani A, Speight PM, Vargas PA. Molecular signature of salivar gland tumors: potential use as diagnostic and prognostic marker. J Oral Pathol Med. 2016;45:101-10.

https://doi.org/10.1111/jop.12329

PMid:25990369 

6. Li GM. Mechanisms and functions of DNA mismatch repair. Cell Res. 2008;18:85-98.

https://doi.org/10.1038/cr.2007.115

PMid:18157157 

7. Olave MC, Graham RP. Mismatch repair deficiency: The what, how and why it is important. Genes Chromosomes Cancer. 2022;61:314-21.

https://doi.org/10.1002/gcc.23015

PMid:34837268 

8. Ijsselsteijn R, Jansen JG, de Wind N. DNA mismatch repair-dependent DNA damage responses and cancer. DNA Repair (Amst). 2020;93:102923.

https://doi.org/10.1016/j.dnarep.2020.102923

PMid:33087264 

9. Kantelinen J, Kansikas M, Candelin S, Hampel H, Smith B, Holm L, et al. Mismatch repair analysis of inherited MSH2 and/or MSH6 variation pairs found in cancer patients. Hum Mutat. 2012;33:1294-301.

https://doi.org/10.1002/humu.22119

PMid:22581703 PMCid:PMC4273566

10. Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;372:1-11.

https://doi.org/10.1186/s13643-021-01626-4

PMid:33781348 PMCid:PMC8008539

11. Landis JR, Koch GG. The measurement of observer agreement for categorical data. Biometrics. 1977;33:159-74.

https://doi.org/10.2307/2529310

PMid:843571

12. Castrilli G, Fabiano A, La Torre G, Marigo L, Piantelli C, Perfetti G, et al. Expression of hMSH2 and hMLH1 proteins of the human DNA mismatch repair system in salivary gland tumors. J Oral Pathol Med. 2002;31:234-8.

https://doi.org/10.1034/j.1600-0714.2002.310407.x

PMid:12076327 

13. Amaral-Silva GK, Dias LM, Mariz BA, Fonseca FP, Rangel AL, Zanella VG, et al. MutSα expression predicts a lower disease-free survival in malignant salivary gland tumors: an immunohistochemical study. Med Oral Patol Oral Cir Bucal. 2022;27:164-73.

https://doi.org/10.4317/medoral.25138

PMid:35218645 PMCid:PMC8898574

14. Soares CD, Morais TML, Carlos R, Jorge J, de Almeida OP, de Carvalho MGF, et al. Sebaceous adenocarcinomas of the major salivary glands: a clinicopathological analysis of 10 cases. Histopathology. 2018;73:585-92.

https://doi.org/10.1111/his.13664

PMid:29856905 

15. Tobón-Arroyave SI, Flórez-Moreno GA, Jaramillo-Cárdenas JF, Arango- Uribe JD, Isaza- Guzmán DM, Rendón- Henao J, et al. Expression of hMLH1 and hMSH2 proteins in pleomorphic adenoma of minor salivary glands: relationship with clinical and histologic findings. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009;108:227-36.

https://doi.org/10.1016/j.tripleo.2009.02.033

PMid:19464205 

16. Hunt JL. Warthin tumors do not have microsatellite instability and express normal DNA mismatch repair proteins. Arch Pathol Lab Med. 2006;130:52-6.

https://doi.org/10.5858/2006-130-52-WTDNHM

PMid:16390238 

17. Ohki K, Kumamoto H, Ichinohasama R, Suzuki M, Yamaguchi T, Echigo S, et al. Genetic analysis of DNA microsatellite loci in salivary gland tumours: comparison with immunohistochemical detection of hMSH2 and p53 proteins. Int J Oral Maxillofac Surg. 2001;30:538-44.

https://doi.org/10.1054/ijom.2001.0161

PMid:11829237 

18. Romero-Laorden N, Castro E. Inherited mutations in DNA repair genes and cancer risk. Curr Probl Cancer. 2017;41:251-64.

https://doi.org/10.1016/j.currproblcancer.2017.02.009

PMid:28454847 

19. Kolodner RD. Mismatch repair: mechanisms and relationship to cancer susceptibility. Trends Biochem Sci. 1995;20:397-401.

https://doi.org/10.1016/S0968-0004(00)89087-8

PMid:8533151 

20. Bateman AC. DNA mismatch repair protein immunohistochemistry - an illustrated guide. Histopathology. 2021;79:128-38.

https://doi.org/10.1111/his.14367

PMid:33829541 

21. Wang C, Zhang L, Vakiani E, Shia J. Detecting mismatch repair deficiency in solid neoplasms: immunohistochemistry, microsatellite instability, or both?. Mod Pathol. 2022;35:1515-28.

https://doi.org/10.1038/s41379-022-01109-4

PMid:35668150 

22. Cilona M, Locatello LG, Novelli L, Gallo O. The Mismatch Repair System (MMR) in Head and Neck Carcinogenesis and Its Role in Modulating the Response to Immunotherapy: A Critical Review. Cancers (Basel). 2020;12:3006.

https://doi.org/10.3390/cancers12103006

PMid:33081243 PMCid:PMC7602801

23. Rito M, Fonseca I. Salivary Gland Neoplasms: Does Morphological Diversity Reflect Tumor Heterogeneity. Pathobiology. 2018;85:85-95.

https://doi.org/10.1159/000479070

PMid:28930752