1. Adamson GD, de Mouzon J, Chambers GM, Zegers-Hochschild F, Mansour R, Ishihara O, et al. International Committee for Monitoring Assisted Reproductive Technology: world report on assisted reproductive technology, 2011. Fertil Steril. 2018;110:1067-80.

https://doi.org/10.1016/j.fertnstert.2018.06.039

PMid:30396551 

2. Vander Borght M, Wyns C. Fertility and infertility: Definition and epidemiology. Clin Biochem. 2018;62:2-10.

https://doi.org/10.1016/j.clinbiochem.2018.03.012

PMid:29555319 

3. Machado V, Botelho J, Proença L, Mendes JJ. Comparisons of Periodontal Status between Females Referenced for Fertility Treatment and Fertile Counterparts: A Pilot Case-Control Study. Int J Environ Res Public Health. 2020;17:1-11.

https://doi.org/10.3390/ijerph17155281

PMid:32707937 PMCid:PMC7432159

4. Khalife D, Khalil A, Itani MN, Khalifeh F, Faour S, Salame A, et al. No association between the presence of periodontal disease and poor IVF outcomes: a pilot study. Int J Womens Health. 2019;11:363-70.

https://doi.org/10.2147/IJWH.S202135

PMid:31354363 PMCid:PMC6572705

5. Zegers-Hochschild F, Adamson GD, Dyer S, Racowsky C, de Mouzon J, Sokol R, et al. The International Glossary on Infertility and Fertility Care, 2017. Fertil Steril. 2017;108:393-406.

https://doi.org/10.1016/j.fertnstert.2017.06.005

PMid:28760517 

6. Bisht S, Faiq M, Tolahunase M, Dada R. Oxidative stress and male infertility. Nat Rev Urol. 2017;14:470-85.

https://doi.org/10.1038/nrurol.2017.69

PMid:28508879 

7. Yildiz Telatar G, Gürlek B, Telatar BC. Periodontal and caries status in unexplained female infertility: A case-control study. J Periodontol. 2021;92:446-54.

https://doi.org/10.1002/JPER.20-0394

PMid:33331005 

8. Machado V, Lopes J, Patrão M, Botelho J, Proença L, Mendes JJ. Validity of the association between periodontitis and female infertility conditions: a concise review. Reproduction. 2020;160:R41-54.

https://doi.org/10.1530/REP-20-0176

PMid:32716008 

9. Maresch CC, Stute DC, Alves MG, Oliveira PF, de Kretser DM, Linn T. Diabetes-induced hyperglycemia impairs male reproductive function: a systematic review. Hum Reprod Update. 2018;24:86-105.

https://doi.org/10.1093/humupd/dmx033

PMid:29136166 

10. Krausz C. Male infertility: pathogenesis and clinical diagnosis. Best Pract Res Clin Endocrinol Metab. 2011;25:271-85.

https://doi.org/10.1016/j.beem.2010.08.006

PMid:21397198 

11. Kellesarian SV, Yunker M, Malmstrom H, Almas K, Romanos GE, Javed F. Male Infertility and Dental Health Status: A Systematic Review. Am J Mens Health. 2018;12:1976-84.

https://doi.org/10.1177/1557988316655529

PMid:27339766 PMCid:PMC6199424

12. Caton J, Armitage G, Berglundh T, Chapple ILC, Jepsen S, Kornman KS, et al. A new classification scheme for periodontal and peri-implant diseases and conditions - Introduction and key changes from the 1999 classification. J Clin Periodontol. 2018;45:S1-8.

https://doi.org/10.1002/JPER.18-0157

PMid:29926946 

13. Chen L, Luo G, Xuan D, Wei B, Liu F, Li J, et al. Effects of non-surgical periodontal treatment on clinical response, serum inflammatory parameters, and metabolic control in patients with type 2 diabetes: a randomized study. J Periodontol. 2012;83:435-43.

https://doi.org/10.1902/jop.2011.110327

PMid:21859323 

14. Tao DY, Zhu JL, Xie CY, Kuang YP, Chai WR, Lo ECM, et al. Relationship between periodontal disease and male infertility: A case-control study. Oral Dis. 2021;27:624-31.

https://doi.org/10.1111/odi.13552

PMid:32702140 

15. Xiong X, Buekens P, Fraser WD, Beck J, Offenbacher S. Periodontal disease and adverse pregnancy outcomes: a systematic review. BJOG. 2006;113:135-43.

https://doi.org/10.1111/j.1471-0528.2005.00827.x

PMid:16411989 

16. Thong EP, Codner E, Laven JSE, Teede H. Diabetes: a metabolic and reproductive disorder in women. Lancet Diabetes Endocrinol. 2020;8:134-49.

https://doi.org/10.1016/S2213-8587(19)30345-6

PMid:31635966 

17. Márquez-Arrico CF, Silvestre-Rangil J, Gutiérrez-Castillo L, Martinez-Herrera M, Silvestre FJ, Rocha M. Association between Periodontal Diseases and Polycystic Ovary Syndrome: A Systematic Review. J Clin Med. 2020;9:1586.

https://doi.org/10.3390/jcm9051586

PMid:32456146 PMCid:PMC7290429

18. Moher D, Shamseer L, Clarke M, Ghersi D, Liberati A, Petticrew M, et al. Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement. Syst Rev. 2015;4:148-60.

https://doi.org/10.1186/2046-4053-4-1

PMid:25554246

19. Schardt C, Adams MB, Owens T, Keitz S, Fontelo P. Utilization of the PICO framework to improve searching PubMed for clinical questions. BMC Med Inform Decis Mak. 2007;7:16.

https://doi.org/10.1186/1472-6947-7-16

PMid:17573961 PMCid:PMC1904193

20. Stang A. Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. Eur J Epidemiol. 2010;25:603-5.

https://doi.org/10.1007/s10654-010-9491-z

PMid:20652370 

21. McCormick F, Cvetanovich GL, Kim JM, Harris JD, Gupta AK, Abrams GD, et al. An assessment of the quality of rotator cuff randomized controlled trials: utilizing the Jadad score and CONSORT criteria. J shoulder Elb Surg. 2013;22:1180-5.

https://doi.org/10.1016/j.jse.2013.01.017

PMid:23510746 

22. Pásztor N, Kárpáti K, Szöllősi J, Keresztúri M, Kozinszky Z, Gorzó I, et al. Association between periodontal status and idiopathic male infertility. J Oral Sci. 2016;58:247-53.

https://doi.org/10.2334/josnusd.15-0586

PMid:27349547 

23. Hart R, Doherty DA, Pennell CE, Newnham IA, Newnham JP. Periodontal disease: a potential modifiable risk factor limiting conception. Hum Reprod. 2012;27:1332-42.

https://doi.org/10.1093/humrep/des034

PMid:22362927 

24. Nwhator SO, Umeizudike KA, Ayanbadejo PO, Opeodu OI, Olamijulo JA, Sorsa T. Another reason for impeccable oral hygiene: oral hygiene-sperm count link. J Contemp Dent Pract. 2014;15:352-8.

https://doi.org/10.5005/jp-journals-10024-1542

PMid:25307820 

25. Šumilin L, Musić L, Puhar I, Sabol I, Japirko I, Kuna K, et al. Diagnostic Accuracy of Salivary aMMP-8 Test in Infertile Women and Blood Finding Analysis. Acta Stomatol Croat. 2022;56:98.

https://doi.org/10.15644/asc56/2/1

PMid:35821727 PMCid:PMC9262112

26. Chidambar C, Shankar S, Agarwal R, Bhushan K, Gururaj S. Evaluation of Periodontal Status among Men Undergoing Infertility Treatment. J Hum Reprod Sci. 2019;12:130-5.

https://doi.org/10.4103/jhrs.JHRS_168_18

PMid:31293327 PMCid:PMC6594118

27. Klinger A, Hain B, Yaffe H, Schonberger O. Periodontal status of males attending an in vitro fertilization clinic. J Clin Periodontol. 2011;38:542-6.

https://doi.org/10.1111/j.1600-051X.2011.01720.x

PMid:21443558 

28. Vasudevan S, Renuka JV, Sylvia DS, Challa R, Padmakanth M, Reddy A. Evaluation of gingival inflammation in patients using ovulation induction drugs before and after scaling. J Contemp Dent Pract. 2013;14:1165-8.

https://doi.org/10.5005/jp-journals-10024-1469

PMid:24858769 

29. Smadi L. Gingival and periodontal changes in patients undergoing in vitro fertilization treatment: A clinical study. Indian J Dent Res. 2017;28:650-4.

https://doi.org/10.4103/ijdr.IJDR_712_16

PMid:29256464 

30. Lalasa G, Murthy KRV, Pavankumar S, Rama Raju GA. Periodontal status in infertile women attending in vitro fertilization clinics. Indian J Dent Res. 2014;25:50-3.

https://doi.org/10.4103/0970-9290.131055

PMid:24748299 

31. Práger N, Pásztor N, Várnagy Á, Kozinszky Z, Baráth Z, Gorzó I, et al. Idiopathic male infertility related to periodontal and caries status. J Clin Periodontol. 2017;44:872-80.

https://doi.org/10.1111/jcpe.12785

PMid:28746727 

32. Kahn BE, Brannigan RE. Obesity and male infertility. Curr Opin Urol. 2017;27:441-5.

https://doi.org/10.1097/MOU.0000000000000417

PMid:28661897 

33. Manfredi-Lozano M, Roa J, Tena-Sempere M. Connecting metabolism and gonadal function: Novel central neuropeptide pathways involved in the metabolic control of puberty and fertility. Front Neuroendocrinol. 2018;48:37-49.

https://doi.org/10.1016/j.yfrne.2017.07.008

PMid:28754629 

34. Martinez-Herrera M, Silvestre FJ, Silvestre-Rangil J, Bañuls C, Rocha M, Hernández-Mijares A. Involvement of insulin resistance in normoglycaemic obese patients with periodontitis: A cross-sectional study. J Clin Periodontol. 2017;44:981-8.

https://doi.org/10.1111/jcpe.12773

PMid:28696512 

35. Liccardo D, Cannavo A, Spagnuolo G, Ferrara N, Cittadini A, Rengo C, et al. Periodontal Disease: A Risk Factor for Diabetes and Cardiovascular Disease. Int J Mol Sci. 2019;20:1414.

https://doi.org/10.3390/ijms20061414

PMid:30897827 PMCid:PMC6470716

36. Song IS, Han K, Park YM, Ji S, Jun SH, Ryu JJ, et al. Severe Periodontitis Is Associated with Insulin Resistance in Non-abdominal Obese Adults. J Clin Endocrinol Metab. 2016;101:4251-9.

https://doi.org/10.1210/jc.2016-2061

PMid:27598510 

37. Song H, Yu Z, Li P, Wang Y, Shi Y. HOMA-IR for predicting clinical pregnancy rate during IVF. Gynecol Endocrinol. 2022;38:33-8.

https://doi.org/10.1080/09513590.2021.1952976

PMid:34263713 

38. Martinez-Herrera M, Silvestre-Rangil J, Silvestre FJ. Association between obesity and periodontal disease. A systematic review of epidemiological studies and controlled clinical trials. Med Oral Patol Oral Cir Bucal. 2017;22:e708.

https://doi.org/10.4317/medoral.21786

PMid:29053651 PMCid:PMC5813989

39. Victor VM, Rocha M, Bañuls C, Alvarez A, de Pablo C, Sanchez-Serrano M, et al. Induction of Oxidative Stress and Human Leukocyte/Endothelial Cell Interactions in Polycystic Ovary Syndrome Patients with Insulin Resistance. J Clin Endocrinol Metab. 2011;96:3115-22.

https://doi.org/10.1210/jc.2011-0651

PMid:21778215