Asmat-Abanto
AS, Espejo-Carrera RE, Honores-Solano TM, Del Castillo-Huertas OM,
Caballero-Alvarado JA, Minchón-Medina CA. Is periodontitis a risk factor for
ischemic stroke?: Systematic review and meta-analysis. J Clin Exp Dent.
2025;17(3):e329-40.
doi:10.4317/jced.62538
https://doi.org/10.4317/jced.62538
__
References
1.
Ma C, Wu M, Gao J, Liu C, Xie Y, Lv Q, et al. Periodontitis and stroke: a
mendelian randomization study. Brain Behav. 2023;13(2):e2888. |
|
|
|
2.
Freiherr Von Seckendorff A, Nomenjanahary MS, Labreuche J, Ollivier V, Di
Meglio L, Dupont S, et al. Periodontitis in ischemic stroke: impact of
Porphyromonas gingivalis on thrombus composition and ischemic stroke
outcomes. Res Pract Thromb Haemost. 2024;8(1):102313. |
|
|
|
3.
Kassebaum NJ, Bernabé E, Dahiya M, Bhandari B, Murray CJ, Marcenes W. Global
burden of severe periodontitis in 1990-2010: a systematic review and meta-regression.
J Dent Res. 2014;93(11):1045-53. |
|
|
|
4.
Kim SR, Son M, Kim YR. The risk of stroke according to statin medication
compliance in older people with chronic periodontitis: an analysis using the
Korea National Health Insurance Service-Senior Cohort Database. Epidemiol
Health. 2022;44:e2022055. |
|
|
|
5.
Sharma A, Sharma A, Chauhan R, Chauhan AS, Parmar M, Thakur S. The
relationship between periodontal disease (PD) and recurrent vascular events
in ischemic stroke/transient ischemic attack (TIA) patients: a hospital-based
cohort study. Cureus. 2023;15(3):e36530. |
|
|
|
6.
Wang C, Yang Y, Cai Q, Gao Y, Cai H, Wu J, et al. Oral microbiome and
ischemic stroke risk among elderly Chinese women. J Oral Microbiol.
2023;15(1):2266655. |
|
|
|
7.
Costea CA, Christodorescu R, Soancă A, Roman A, Micu IC, Stratul ȘI, et al.
Periodontitis in ischemic stroke patients: case definition challenges of the
New Classification Scheme (2018). J Clin Med. 2022;11(3):520. |
|
|
|
8.
Vago EL, Frange C, DA Paz Oliveira G, Juliano ML, Machado MA, Coelho FMS. The
association between sleep disturbances and tooth loss among post-stroke
patients. Arq Neuropsiquiatr. 2022;80(2):173-79. |
|
|
|
9.
Tuominen H, Taina M, Puranen M, Onatsu J, Huumonen S, Vanninen R. Serum
high-sensitive C-reactive protein may reflect periodontitis in patients with
stroke. in vivo. 2020;34(5):2829-35. |
|
|
|
10.
Fagundes NCF, Almeida APCPSC, Vilhena KFB, Magno MB, Maia LC, Lima RR.
Periodontitis as a risk factor for stroke: a systematic review and
meta-analysis. Vasc Health Risk Manag. 2019;15:519-32. |
|
|
|
11.
Stănescu I, Bulboacă AE, Micu IC, Bolboacă SD, Feștilă DG, Bulboacă AC, et
al. Gender differences in the levels of periodontal destruction, behavioral
risk factors and systemic oxidative stress in ischemic stroke patients: a
cohort pilot study. J Clin Med. 2020;9(6):1744. |
|
|
|
12.
Schenkein HA, Papapanou PN, Genco R, Sanz M. Mechanisms underlying the
association between periodontitis and atherosclerotic disease. Periodontol
2000. 2020;83:90-106. |
|
|
|
13.
Torrungruang K, Vathesatogkit P, Mahanonda R, Thienpramuk L. Periodontitis
and hypertension are linked through systemic inflammation: a 5-year
longitudinal study. J Clin Periodontol. 2024;51(5):536-46. |
|
|
|
14.
Dewan M, Pandit AK, Goyal L. Association of periodontitis and gingivitis with
stroke: a systematic review and meta-analysis. Dent Med Probl. 2024;61(3):407-15. |
|
|
|
15.
Page MJ, Moher D, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al.
PRISMA 2020 explanation and elaboration: updated guidance and exemplars for
reporting systematic reviews. BMJ. 2021;372(160):n160. |
|
|
|
16.
Schünemann HJ, Cuello C, Akl EA, Mustafa RA, Meerpohl JJ, Thayer K, et al.
GRADE guidelines: 18. How ROBINS-I and other tools to assess risk of bias in
nonrandomized studies should be used to rate the certainty of a body of
evidence. J Clin Epidemiol. 2019;111:105-14. |
|
|
|
17.
Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al.
The PRISMA 2020 statement: an updated guideline for reporting systematic
reviews. BMJ. 2021;372:n71. |
|
|
|
18.
González Díaz ME, Morales Reyes C, Pupo Méndez G, Doncel Pérez C. Estudio
preliminar del estado periodontal de pacientes con infarto cerebral
isquémico. Rev Méd Electrón. 2018;40(3):588-601. |
|
|
|
19.
Grau AJ, Becher H, Ziegler CM, Lichy C, Buggle F, Kaiser C, et al.
Periodontal disease as a risk factor for ischemic stroke. Stroke.
2004;35(2):496-501. |
|
|
|
20.
Abolfazli N, Ghoreishizadeh A, Ayramlu H, Ghavimi M, Ghoreishizadeh M, Salehsaber
F. Periodontal disease and risk of cerebral ischemic stroke. J Neurol Sci
[Turk]. 2011;28(3):307-16. |
|
|
|
21.
Ghizoni JS, Taveira LA, Garlet GP, Ghizoni MF, Pereira JR, Dionísio TJ, et
al. Increased levels of Porphyromonas gingivalis are associated with ischemic
and hemorrhagic cerebrovascular disease in humans: an in vivo study. J Appl
Oral Sci. 2012;20(1):104-12. |
|
|
|
22.
Leira Y, López-Dequidt I, Arias S, Rodríguez-Yáñez M, Leira R, Sobrino T, et
al. Chronic periodontitis is associated with lacunar infarct: a case-control
study. Eur J Neurol. 2016;23(10):1572-9. |
|
|
|
23.
Leira Y, Rodríguez-Yáñez M, Arias S, López-Dequidt I, Campos F, Sobrino T, et
al. Periodontitis as a risk indicator and predictor of poor outcome for
lacunar infarct. J Clin Periodontol. 2019;46(1):20-30. |
|
|
|
24.
Sen S, Giamberardino LD, Moss K, Morelli T, Rosamond WD, Gottesman RF, et al.
Periodontal disease, regular dental care use, and incident ischemic stroke.
Stroke. 2018;49(2):355-62. |
|
|
|
25.
Lee YT, Tsai CF, Yen YC, Huang LK, Chao SP, Hu LY, et al. Periodontitis is a
potential risk factor for transient ischemic attack and minor ischemic stroke
in young adults: a nationwide population-based cohort study. J Periodontol.
2022;93(12):1848-56. |
|
|
|
26.
Hansen GM, Egeberg A, Holmstrup P, Hansen PR. Relation of Periodontitis to
risk of cardiovascular and all-cause mortality (from a Danish Nationwide
Cohort Study). Am J Cardiol. 2016;118(4):489-93. |
|
|
|
27.
Wu T, Trevisan M, Genco RJ, Dorn JP, Falkner KL, Sempos CT. Periodontal
disease and risk of cerebrovascular disease: the first national health and
nutrition examination survey and its follow-up study. Arch Intern Med.
2000;160(18):2749-55. |
|
|
|
28.
Lin HW, Chen CM, Yeh YC, Chen YY, Guo RY, Lin YP, et al. Dental treatment
procedures for periodontal disease and the subsequent risk of ischaemic
stroke: a retrospective population-based cohort study. J Clin Periodontol.
2019;46(6):642-49. |
|
|
|
29.
Dörfer CE, Becher H, Ziegler CM, Kaiser C, Lutz R, Jörss D, et al. The
association of gingivitis and periodontitis with ischemic stroke. J Clin
Periodontol. 2004;31(5):396-401. |
|
|
|
30.
Hashemipour MA, Afshar AJ, Borna R, Seddighi B, Motamedi A. Gingivitis and
periodontitis as a risk factor for stroke: a case-control study in the
Iranian population. Dent Res J (Isfahan). 2013;10(5):613-9. |
|
|
|
31.
Lafon A, Tala S, Ahossi V, Perrin D, Giroud M, Béjot Y. Association between
periodontal disease and non-fatal ischemic stroke: a case-control study. Acta
Odontol Scand. 2014;72(8):687-93. |
|
|
|
32.
Pradeep AR, Hadge P, Arjun Raju P, Shetty SR, Shareef K, Guruprasad CN.
Periodontitis as a risk factor for cerebrovascular accident: a case-control
study in the Indian population. J Periodontal Res. 2010;45(2):223-8. |
|
|
|
33.
Sim SJ, Kim HD, Moon JY, Zavras AI, Zdanowicz J, Jang SJ, et al.
Periodontitis and the risk for non-fatal stroke in Korean adults. J
Periodontol. 2008;79(9):1652-8. |
|
|
|
34.
Rothwell PM. Atherothrombosis and ischaemic stroke. BMJ.
2007;334(7590):379-80. |
|
|
|
35.
Leira Y, Seoane J, Blanco M, Rodríguez-Yáñez M, Takkouche B, Blanco J, et al.
Association between periodontitis and ischemic stroke: a systematic review
and meta-analysis. Eur J Epidemiol. 2017;32(1):43-53. |
|
|
|
36.
Cerda J, Vera C, Rada G. Odds ratio: theoretical and practical issues. Rev
Med Chil. 2013;141(10):1329-35. |
|
|
|
37.
George A, Stead TS, Ganti L. What's the Risk: Differentiating risk ratios,
odds ratios, and hazard ratios? Cureus. 2020;12(8):e10047. |
|
|
|
38.
Heitz-Mayfield LJA. Conventional diagnostic criteria for periodontal diseases
(plaque-induced gingivitis and periodontitis). Periodontol 2000.
2024;95(1):10-19. |
|
|
|
39.
Leira Y, Rodríguez-Yáñez M, Arias S, López-Dequidt I, Campos F, Sobrino T, et
al. Periodontitis is associated with systemic inflammation and vascular
endothelial dysfunction in patients with lacunar infarct. J Periodontol.
2019;90(5):465-74. |